Development Level

Tbio 12 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal vitreous body morphol... 1 | 10
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart atrium 1 | 4
increased startle reflex 1 | 112

Disease

Carcinoma 11 | 11,493
osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
Autosomal recessive predisposition 8 | 1,442
psoriasis 8 | 6,694
Hereditary coproporphyria 7 | 8
Porphyria 7 | 10
lung cancer 7 | 4,740
Acute intermittent porphyria 6 | 15
Variegate Porphyria 6 | 10
malignant mesothelioma 6 | 3,232
Anemia 5 | 365
Anemia, Hemolytic 5 | 55
Erythropoietic protoporphyria 5 | 15
Photosensitivity of skin 5 | 51
Porphyria cutanea tarda 5 | 12
Abdominal Pain 4 | 98
Constipation 4 | 181
Dyschezia 4 | 135
Hepatomegaly 4 | 285
Hypertensive disease 4 | 292
Hypertrichosis 4 | 46
Intellectual disability 4 | 1,016
Muscle hypotonia 4 | 571
Seizures 4 | 596
Vomiting 4 | 116
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Abnormal blistering of the skin 3 | 54
Blister of skin 3 | 54
Cancer 3 | 2,499
Cholelithiasis 3 | 33
Cutaneous porphyria 3 | 6
Diarrhea 3 | 253
Dull intelligence 3 | 645
Elevated heart rate 3 | 25
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Pediatric failure to thrive 3 | 365
Peripheral Neuropathy 3 | 134
Poor school performance 3 | 645
Proteinuria 3 | 144
Respiratory Paralysis 3 | 7
Skin bulla 3 | 54
Splenomegaly 3 | 190
Tachycardia 3 | 43
Thin skin 3 | 47
astrocytic glioma 3 | 2,597
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Acidosis, Lactic 2 | 97
Alopecia 2 | 115
Anxiety 2 | 136
Anxiety disease 2 | 113
Blepharoptosis 2 | 231
Decreased liver function 2 | 24
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Gliosis 2 | 56
Heart disease 2 | 306
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperreflexia 2 | 209
Hypertension 2 | 396
Hypertrophic Cardiomyopathy 2 | 117
Increased serum lactate 2 | 60
Infantile onset 2 | 238
Lactic acidemia 2 | 95
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Liver carcinoma 2 | 240
Liver disease 2 | 237
Liver diseases 2 | 87
Liver dysfunction, mild 2 | 24
Mood swings 2 | 77
Muscle Spasticity 2 | 195
Nausea and vomiting 2 | 97
Neonatal Jaundice 2 | 30
Neuropathy 2 | 261
Ophthalmoplegia 2 | 106
Paresthesia 2 | 32
Phenotypic variability 2 | 150
Progressive disorder 2 | 142
Psychotic Disorders 2 | 151
Respiratory Failure 2 | 104
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
Toxic encephalopathy 2 | 141
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
cystic fibrosis 2 | 1,696

Tissue

Endocrine System 15 | 18,159
Digestive Tract 14 | 17,369
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Nervous System 13 | 16,725
Respiratory system 13 | 16,393

Target Family

Enzyme 14 | 4,145
Non-IDG 1 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 15 | 15
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome c oxidase assembly protein COX15 homolog COX15 Tbio Enzyme -1.37513 23.0 104
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.60266 40.9 154
5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 Tbio Enzyme -1.80580 61.7 153
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial CPOX Tbio Enzyme -2.05504 112.4 87
Protoporphyrinogen oxidase PPOX Tchem Enzyme -2.47389 296.8 173
Porphobilinogen deaminase HMBS Tbio Enzyme -2.78202 588.5 255
Ferritin, mitochondrial FTMT Tbio Non-IDG -1.11598 13.8 34
UDP-glucuronosyltransferase 2B11 UGT2B11 Tbio Enzyme -0.26858 1.79 52
Delta-aminolevulinic acid dehydratase ALAD Tbio Enzyme -3.02024 1068.6 166
Biliverdin reductase A BLVRA Tbio Enzyme -2.21992 173.6 221