Development Level

Tbio 16 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
enlarged heart 1 | 210
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112

Disease

ovarian cancer 15 | 8,520
osteosarcoma 13 | 7,950
Carcinoma 12 | 11,493
medulloblastoma, large-cell 12 | 6,241
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
Kidney cancer 7 | 2,613
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
group 3 medulloblastoma 6 | 4,104
primitive neuroectodermal tumor 6 | 3,035
Schizophrenia 5 | 1,160
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Centronuclear myopathy 3 | 27
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Neurodegenerative disease 3 | 414
Yunis-Varon syndrome 3 | 6
astrocytic glioma 3 | 2,597
invasive ductal carcinoma 3 | 2,951
medulloblastoma 3 | 720
psoriasis 3 | 6,694
Abnormality of metabolism/homeostasis 2 | 134
Adenoid Cystic Carcinoma 2 | 99
Anxiety 2 | 136
Anxiety disease 2 | 113
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Adenoid Cystic 2 | 99
Cataract 2 | 297
Congenital deafness 2 | 185
Deafness 2 | 198
Depressive disorder 2 | 409
Dilated ventricles (finding) 2 | 121
Endometrial cancer 2 | 311
Fatigue 2 | 182
Hearing Loss, Partial 2 | 185
Lens Opacities 2 | 231
Liver cancer 2 | 604
Long narrow head 2 | 75
Lung Neoplasms 2 | 232
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Neuropathy 2 | 261
Oculocerebrorenal syndrome 2 | 29
Orbital separation excessive 2 | 244
Pain 2 | 103
Pick disease 2 | 1,894
Polymicrogyria 2 | 48
Seizures 2 | 596
Status Epilepticus 2 | 98
Syndactyly of the toes 2 | 45
Turridolichocephaly 2 | 75
Ventricular Septal Defects 2 | 119
Whipple disease 2 | 6
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
hearing impairment 2 | 199
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Congenital hypoplasia of clavicle 1 | 18
Cowden disease 1 | 18
Facial asymmetry 1 | 32
Fissured tongue 1 | 25
Gastrointestinal Hemorrhage 1 | 52
Hematologic Neoplasms 1 | 22
Hypoplastic finger 1 | 17
Mucosal telangiectasiae 1 | 14
Multiple, subcutaneous nodules 1 | 53
Port-Wine Stain 1 | 8
Pyramidal tract syndrome 1 | 2
Short finger 1 | 17
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
Thyroid Gland Follicular Adenoma 1 | 9
Upper motor neuron dysfunction 1 | 2
pancreatic ductal carcinoma 1 | 11

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Cardiovascular System 21 | 15,192
Urinary Tract 21 | 16,678

Target Family

Enzyme 11 | 4,145
Kinase 8 | 634
Non-IDG 3 | 12,091

PathwayCommons: smpdb Pathway

http://identifiers.org/smpdb/S... 22 | 22
http://identifiers.org/smpdb/S... 78 | 78
http://identifiers.org/smpdb/S... 60 | 60
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 59 | 59
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 58 | 58
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 47 | 47
http://identifiers.org/smpdb/S... 45 | 45
http://identifiers.org/smpdb/S... 38 | 38
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 37 | 37
http://identifiers.org/smpdb/S... 36 | 36
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 35 | 35
http://identifiers.org/smpdb/S... 34 | 34
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 33 | 33
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32
http://identifiers.org/smpdb/S... 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tbio Enzyme -1.36243 23.0 109
Type I inositol 3,4-bisphosphate 4-phosphatase INPP4A Tbio Enzyme -1.12941 13.9 47
Inositol polyphosphate 1-phosphatase INPP1 Tbio Enzyme -1.24647 18.1 100
Inositol polyphosphate multikinase IPMK Tbio Kinase -1.55144 39.0 159
Inositol-trisphosphate 3-kinase A ITPKA Tchem Kinase -1.42824 28.0 156
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 PLCD3 Tbio Enzyme -1.21205 17.5 66
Inositol monophosphatase 1 IMPA1 Tclin Enzyme -2.34557 211.7 94
Inositol oxygenase MIOX Tbio Enzyme -1.73181 60.0 146
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126
Activating molecule in BECN1-regulated autophagy protein 1 AMBRA1 Tbio Non-IDG -1.56899 41.8 254