Development Level

Tbio 14 | 10,625
Tchem 5 | 1,890
Tclin 2 | 602

IMPC Term

decreased NK T cell number 2 | 28
abnormal hair growth 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
decreased CD5-positive gamma-d... 1 | 3
decreased CD8-positive, alpha-... 1 | 26
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased circulating alanine ... 1 | 53
decreased circulating glucose ... 1 | 121
decreased effector memory CD8-... 1 | 24
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
increased CD4-positive, CD25-p... 1 | 18
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating magnesiu... 1 | 10
increased effector memory CD8-... 1 | 14
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
sparse hair 1 | 6
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 13 | 8,492
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
medulloblastoma, large-cell 8 | 6,234
glioblastoma 7 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
osteosarcoma 7 | 7,933
pilocytic astrocytoma 7 | 3,086
Breast cancer 6 | 3,099
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
psoriasis 6 | 6,685
atypical teratoid / rhabdoid tumor 5 | 4,369
invasive ductal carcinoma 5 | 2,950
lung cancer 5 | 4,473
pancreatic cancer 5 | 2,300
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 1,563
Gaucher's disease 4 | 25
adult high grade glioma 4 | 2,148
aldosterone-producing adenoma 4 | 664
astrocytic glioma 4 | 2,241
group 3 medulloblastoma 4 | 2,254
lung carcinoma 4 | 2,844
malignant mesothelioma 4 | 3,163
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
pituitary cancer 4 | 1,972
Alzheimer's disease 3 | 644
Cancer 3 | 2,346
Down syndrome 3 | 548
Krabbe disease 3 | 11
Multiple Sclerosis 3 | 498
Neuropathy 3 | 210
Peripheral Neuropathy 3 | 303
Pick disease 3 | 1,893
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,670
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,714
mucosa-associated lymphoid tissue lymphoma 3 | 480
progressive supranuclear palsy 3 | 674
Amyotrophic Lateral Sclerosis 2 | 432
Atopic dermatitis 2 | 944
Farber lipogranulomatosis 2 | 9
Gangliosidosis 2 | 17
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Leukodystrophy 2 | 30
Metachromatic leukodystrophy 2 | 13
Multiple myeloma 2 | 1,328
Neurodegenerative disease 2 | 383
Posterior amorphous corneal dystrophy 2 | 9
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
dermatomyositis 2 | 967
diabetes mellitus 2 | 1,663
group 4 medulloblastoma 2 | 1,875
inclusion-cell disease 2 | 15
interstitial cystitis 2 | 2,299
medulloblastoma 2 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group A ependymoma 2 | 1,511
primitive neuroectodermal tumor 2 | 3,031
spina bifida 2 | 1,064
ulcerative colitis 2 | 2,087
urothelial carcinoma 2 | 318
Anemia 1 | 252
Barrett's esophagus 1 | 185
Bipolar Disorder 1 | 266
Cardiomyopathy 1 | 110
Cerebrovascular disease 1 | 231
Dementia 1 | 129
Disease Progression 1 | 125
Globoid cell leukodystrophy 1 | 1
Heart disease 1 | 279
Kidney disease 1 | 397
Leukodystrophy metachromatic 1 | 1
Leukodystrophy, Metachromatic 1 | 1
Leukodystrophy, globoid cell 1 | 1
Lymphoma 1 | 57
Lymphoma, Follicular 1 | 20
Melanoma 1 | 261
Metachromatic Leukodystrophy, Adult-Type (disorder) 1 | 2
Metachromatic Leukodystrophy, Infant 1 | 1
Metachromatic leukodystrophy, juvenile type 1 | 2
Mucosulfatidosis 1 | 5
Multiple sulfatase deficiency 1 | 3
Parkinson Disease 1 | 105
Parkinson's disease 1 | 364
Retinitis pigmentosa 1 | 156
Stomach Neoplasms 1 | 282
Thrombocytopenia 1 | 105
X-linked cerebral adrenoleukodystrophy 1 | 115
cone-rod dystrophy 1 | 60
glioblastoma multiforme 1 | 347

Tissue

Cardiovascular System 21 | 17,958
Blood and immune system 20 | 17,995
Digestive Tract 20 | 18,473
Endocrine System 20 | 18,512
Female tissues 20 | 18,647
Liver and Pancreas 20 | 18,136
Male tissues 20 | 17,969
Nervous System 20 | 18,561
Respiratory system 20 | 17,484
Skin and soft tissues 20 | 18,115
Urinary Tract 20 | 18,444

Target Family

Enzyme 19 | 4,146
Kinase 2 | 634

PathwayCommons: smpdb Pathway

Sphingolipid Metabolism 21 | 21
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alkaline ceramidase 3 ACER3 Tbio Enzyme -2.04148 105.9 85
Phosphatidylcholine:ceramide cholinephosphotransferase 1 SGMS1 Tbio Enzyme -1.57073 38.2 0
Arylsulfatase A ARSA Tbio Enzyme -2.49720 316.0 305
Galactosylceramide sulfotransferase GAL3ST1 Tbio Enzyme -1.19141 12.3 86
Galactocerebrosidase GALC Tbio Enzyme -2.55010 348.0 123
Sialidase-3 NEU3 Tbio Enzyme -1.98706 109.4 23
Sphingosine-1-phosphate phosphatase 2 SGPP2 Tbio Enzyme -0.61396 4.96 67
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.15284 141.0 260
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.67761 46.3 182
3-ketodihydrosphingosine reductase KDSR Tbio Enzyme -1.14440 12.5 96