Development Level

Tclin 7 | 602
Tbio 3 | 10,625
Tchem 1 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

improved glucose tolerance 2 | 56
abnormal bone structure 1 | 131
decreased bone mineral content 1 | 157
decreased circulating alkaline... 1 | 41
increased circulating serum al... 1 | 25

Disease

Cancer 5 | 2,346
Gastric ulcer 5 | 34
Gastritis 5 | 44
Peptic ulcer 5 | 22
Zollinger-Ellison Syndrome 5 | 14
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
ovarian cancer 5 | 8,484
Diarrhea 4 | 155
Dyspepsia 4 | 34
Gastroesophageal reflux disease 4 | 37
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
psoriasis 4 | 6,685
Acromegaly 3 | 40
Adenoma 3 | 165
Constipation 3 | 43
Duodenal Ulcer due to H. Pylori 3 | 7
Duodenal ulcer 3 | 20
Duodenal ulcer disease 3 | 7
Epilepsy 3 | 346
Erosive esophagitis 3 | 6
Esophagitis 3 | 26
Gastric Hypersecretory Conditions 3 | 5
Irritable bowel syndrome 3 | 59
Liver Cirrhosis 3 | 101
Maintenance of Healing Duodenal Ulcer 3 | 7
Multiple endocrine adenomas 3 | 3
Pain agnosia 3 | 99
Peptic reflux disease 3 | 4
Pick disease 3 | 1,893
Systemic mast cell disease 3 | 12
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,665
diabetes mellitus 3 | 1,663
glioblastoma 3 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung cancer 3 | 4,466
osteosarcoma 3 | 7,933
pediatric high grade glioma 3 | 2,712
primary pancreatic ductal adenocarcinoma 3 | 1,271
ulcerative colitis 3 | 2,087
Achalasia 2 | 11
Adenocarcinoma 2 | 115
Anemia 2 | 252
Arthritis 2 | 248
Asthma 2 | 349
Barrett Esophagus 2 | 16
Bile reflux 2 | 8
Carcinoma 2 | 2,147
Down syndrome 2 | 548
Drug-Induced Liver Injury 2 | 118
Dumping syndrome 2 | 9
Duodenitis 2 | 8
Duodenogastric reflux 2 | 8
Esophageal varix 2 | 10
Gastric outlet obstruction 2 | 6
Gastro-esophageal reflux disease with esophagitis 2 | 3
Hyperinsulinemic hypoglycemia 2 | 17
Hypoglycemia 2 | 81
Hypokalemia 2 | 40
Kidney disease 2 | 396
Maintenance of Healing Erosive Esophagitis 2 | 2
Maintenance of Healing Gastroesophageal Reflux 2 | 2
Multiple Endocrine Neoplasia Type 1 2 | 30
NSAID-Induced Gastric Ulcer 2 | 4
Open-angle glaucoma 2 | 26
Osteoarthritis in Patients at High Ulcer Risk 2 | 7
Pancreatic cholera 2 | 6
Pancreatitis 2 | 97
Parkinson's disease 2 | 364
Pathological Gastric Hypersecretory Condition 2 | 2
Pernicious anemia 2 | 10
Pituitary adenoma 2 | 35
Prevention of NSAID-Induced Gastric Ulcer 2 | 3
Rheumatoid Arthritis in Patient at High Ulcer Risk 2 | 7
Short bowel syndrome 2 | 16
Stomach Neoplasms 2 | 282
Substance Withdrawal Syndrome 2 | 52
Varicose veins 2 | 15
Vitamin B12 deficiency 2 | 20
acute myeloid leukemia 2 | 780
astrocytoma 2 | 1,493
atypical teratoid / rhabdoid tumor 2 | 4,369
ependymoma 2 | 2,514
pilocytic astrocytoma 2 | 3,086
posterior fossa group B ependymoma 2 | 1,530
Absence seizure 1 | 12
Cholelithiasis 1 | 14
Dyskinesia of esophagus 1 | 3
Gastroduodenitis 1 | 4
Hiatus hernia 1 | 7
Hyperprolactinemia 1 | 22
Laryngitis 1 | 2
Nasal discharge 1 | 26
Peptic ulcer disease 1 | 11
Pneumoconiosis 1 | 14
Polycystic liver disease 1 | 10
X-linked myopathy with excessive autophagy 1 | 2
angle-closure glaucoma 1 | 7

Tissue

Blood and immune system 11 | 17,995
Digestive Tract 11 | 18,473
Endocrine System 11 | 18,512
Female tissues 11 | 18,647
Liver and Pancreas 11 | 18,136
Nervous System 11 | 18,561
Respiratory system 11 | 17,484
Skin and soft tissues 11 | 18,115
Urinary Tract 11 | 18,444
Cardiovascular System 10 | 17,958
Male tissues 10 | 17,969

Target Family

GPCR 4 | 406
Transporter 3 | 473
Non-IDG 2 | 11,971
Enzyme 1 | 4,146
Ion Channel 1 | 341

PathwayCommons: smpdb Pathway

Pantoprazole Action Pathway 11 | 11
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.76953 6.01 159
Chloride intracellular channel protein 2 CLIC2 Tbio Ion Channel -1.42344 26.3 95
Somatostatin SST Tchem Non-IDG -4.13259 13272.3 348
Chloride anion exchanger SLC26A3 Tbio Transporter -2.80845 656.2 41
Gastrin GAST Tbio Non-IDG -3.89977 8089.1 283
Histamine H2 receptor HRH2 Tclin GPCR -3.20808 1579.7 225
Carbonic anhydrase 1 CA1 Tclin Enzyme -3.28759 1962.0 427
Potassium-transporting ATPase alpha chain 1 ATP4A Tclin Transporter -3.77806 5994.1 21
Gastrin/cholecystokinin type B receptor CCKBR Tclin GPCR -2.73628 514.7 211
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.68668 43.9 142