Development Level

Tchem 13 | 1,890
Tbio 10 | 10,625
Tclin 3 | 602
Tdark 2 | 7,003

IMPC Phenotype

abnormal epididymis morphology 1 | 31
abnormal testis morphology 1 | 30
decreased body length 1 | 108
decreased circulating insulin ... 1 | 75
enlarged epididymis 1 | 27
preweaning lethality, incomple... 1 | 260
small testis 1 | 37

Disease

lung cancer 14 | 4,473
osteosarcoma 14 | 7,933
ovarian cancer 14 | 8,491
psoriasis 14 | 6,685
Cancer 13 | 2,346
lung carcinoma 12 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
non-small cell lung cancer 11 | 2,798
interstitial cystitis 10 | 2,299
medulloblastoma, large-cell 10 | 6,234
glioblastoma 9 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
pancreatic cancer 9 | 2,300
tuberculosis 9 | 1,563
Hypertension 8 | 293
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
invasive ductal carcinoma 8 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
pilocytic astrocytoma 8 | 3,086
ulcerative colitis 8 | 2,087
Asthma 7 | 349
lung adenocarcinoma 7 | 2,714
malignant mesothelioma 7 | 3,163
Prostatic Neoplasms 6 | 471
adrenocortical carcinoma 6 | 1,427
astrocytoma 6 | 1,493
cystic fibrosis 6 | 1,670
oligodendroglioma 6 | 2,849
Atherosclerosis 5 | 275
Cerebrovascular disease 5 | 231
Obesity 5 | 616
Osteoarthritis 5 | 96
Rheumatoid Arthritis 5 | 1,170
atypical teratoid / rhabdoid tumor 5 | 4,369
diabetes mellitus 5 | 1,663
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
primitive neuroectodermal tumor 5 | 3,031
Actinic keratosis 4 | 22
Arthritis 4 | 248
Atopic dermatitis 4 | 944
Breast cancer 4 | 3,098
Dysmenorrhea 4 | 19
Hyperalgesia 4 | 71
Juvenile rheumatoid arthritis 4 | 105
Liver disease 4 | 219
Lung Neoplasms 4 | 171
Menorrhagia 4 | 8
Pain 4 | 70
Patent ductus arteriosus 4 | 23
Peripheral Neuropathy 4 | 303
Reperfusion Injury 4 | 84
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
cutaneous lupus erythematosus 4 | 1,056
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
head and neck cancer 4 | 270
pediatric high grade glioma 4 | 2,712
posterior fossa group A ependymoma 4 | 1,511
subependymal giant cell astrocytoma 4 | 2,287
Adverse reaction to drug 3 | 54
Ankylosing spondylitis 3 | 138
Bursitis 3 | 10
Chronic ulcerative proctitis 3 | 7
Chronic ulcerative rectosigmoiditis 3 | 4
Colonic Neoplasms 3 | 126
Coronary artery disease 3 | 240
Drug allergy 3 | 36
Endometriosis 3 | 535
Esophageal Neoplasms 3 | 67
Fever 3 | 34
Gout 3 | 93
Headache disorder 3 | 20
Heart failure 3 | 80
Hypertensive disease 3 | 193
Joint pain 3 | 8
Kidney Failure, Chronic 3 | 45
Kidney disease 3 | 397
Liver carcinoma 3 | 217
Mammary Neoplasms 3 | 410
Migraine 3 | 79
Myocardial Infarction 3 | 126
Nasal discharge 3 | 26
Pleurisy 3 | 18
Sinus headache 3 | 17
Stomach Neoplasms 3 | 282
Synovitis 3 | 72
Tendinitis 3 | 13
Tenosynovitis 3 | 15
Ulcerative colitis in remission 3 | 4
Urticaria 3 | 53
acute myeloid leukemia 3 | 785
adult high grade glioma 3 | 2,148
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
nephrosclerosis 3 | 329
pancreatic carcinoma 3 | 567

Tissue

Blood and immune system 28 | 17,994
Cardiovascular System 28 | 17,957
Digestive Tract 28 | 18,472
Endocrine System 28 | 18,511
Female tissues 28 | 18,646
Liver and Pancreas 28 | 18,135
Male tissues 28 | 17,968
Nervous System 28 | 18,560
Skin and soft tissues 28 | 18,114
Urinary Tract 28 | 18,443
Respiratory system 27 | 17,483

Target Family

Enzyme 21 | 4,146
Non-IDG 7 | 11,969

PathwayCommons: smpdb Pathway

Nepafenac Action Pathway 28 | 28
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 2E1 CYP2E1 Tbio Non-IDG -3.39793 2573.0 350
Cytochrome P450 2B6 CYP2B6 Tchem Non-IDG -3.69934 5025.3 171
Cytochrome P450 2U1 CYP2U1 Tbio Non-IDG -1.22155 18.8 71
Prostaglandin E synthase PTGES Tchem Enzyme -3.02917 1099.8 145
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.05115 12041.6 648
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.11127 1228.9 241
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.21714 1594.9 391
Docosahexaenoic acid omega-hydroxylase CYP4F3 CYP4F3 Tbio Enzyme -1.69323 47.4 107
Prostamide/prostaglandin F synthase FAM213B Tdark Enzyme -0.09691 0.67 56
Arachidonate 5-lipoxygenase ALOX5 Tclin Enzyme -3.10636 1353.0 439