Development Level

Tbio 12 | 10,625
Tchem 1 | 1,890

IMPC Phenotype

abnormal behavior 1 | 226
abnormal digit morphology 1 | 13
hypoactivity 1 | 89

Disease

ovarian cancer 8 | 8,491
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
invasive ductal carcinoma 5 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
psoriasis 4 | 6,685
Multiple myeloma 3 | 1,327
acute myeloid leukemia 3 | 785
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,714
lung cancer 3 | 4,473
osteosarcoma 3 | 7,933
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
ulcerative colitis 3 | 2,087
Breast cancer 2 | 3,098
Lactic acidosis 2 | 43
Leigh disease 2 | 81
Maple syrup urine disease 2 | 25
Neurodegenerative disease 2 | 383
Obesity 2 | 616
Ornithine translocase deficiency 2 | 5
Stomach Neoplasms 2 | 282
Waldenstrons macroglobulinemia 2 | 764
breast carcinoma 2 | 1,614
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,670
glioblastoma 2 | 5,572
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
nephrosclerosis 2 | 329
pancreatic cancer 2 | 2,300
pilocytic astrocytoma 2 | 3,086
primitive neuroectodermal tumor 2 | 3,031
sonic hedgehog group medulloblastoma 2 | 1,482
3-ketothiolase deficiency 1 | 1
Alpha-Methylacetoacetic Aciduria 1 | 1
Amino acid metabolic disorder 1 | 5
Ankylosing spondylitis 1 | 138
Bone Diseases 1 | 8
Cancer 1 | 2,346
Charcot-Marie-Tooth disease 1 | 74
Chronic granulomatous disease 1 | 13
Chronic obstructive pulmonary disease 1 | 147
Citrullinemia 1 | 13
Congenital ocular coloboma (disorder) 1 | 12
Corneal dystrophy 1 | 15
Cystinuria 1 | 18
D-2-hydroxyglutaric aciduria 1 | 9
Deficiency of acetyl-CoA acetyltransferase 1 | 1
Deficiency of glutamate decarboxylase 1 | 1
Detrusor sphincter dyssynergia 1 | 8
Disease Progression 1 | 125
Dystonia 1 | 77
EPILEPSY, PYRIDOXINE-DEPENDENT 1 | 1
Epilepsy 1 | 346
Finding of Mean Corpuscular Hemoglobin 1 | 14
Gaucher's disease 1 | 25
Glutaric aciduria 1 1 | 1
Holocarboxylase synthetase deficiency 1 | 7
Homocarnosinosis 1 | 2
Huntington's disease 1 | 72
Hyperinsulinemic hypoglycemia 1 | 17
Hyperinsulinism 1 | 63
Hyperlysinemia 1 | 6
Hypertension 1 | 293
Hypoglycemia 1 | 81
Impotence 1 | 45
Kidney Failure, Chronic 1 | 45
Leigh syndrome 1 | 34
Lysinuric protein intolerance 1 | 15
NADH cytochrome B5 reductase deficiency 1 | 2
Neuropathy 1 | 210
Orotic aciduria 1 | 16
Osteoporosis 1 | 259
Peroxisomal Disorders 1 | 2
Precancerous Conditions 1 | 69
Pseudoxanthoma elasticum 1 | 19
Psoriatic arthritis 1 | 85
Pyridoxine-dependent epilepsy 1 | 1
Pyruvate decarboxylase deficiency 1 | 15
Reye syndrome 1 | 11
Seizures 1 | 95
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Urea cycle disorder 1 | 7
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
adult high grade glioma 1 | 2,148
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
beta-ketothiolase deficiency 1 | 13
chronic rhinosinusitis 1 | 512
cystic fibrosis and chronic rhinosinusitis 1 | 213
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
inflammatory breast cancer 1 | 404
mucosa-associated lymphoid tissue lymphoma 1 | 480
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,563

Tissue

Blood and immune system 13 | 17,994
Cardiovascular System 13 | 17,957
Digestive Tract 13 | 18,472
Endocrine System 13 | 18,511
Female tissues 13 | 18,646
Liver and Pancreas 13 | 18,135
Male tissues 13 | 17,968
Nervous System 13 | 18,560
Respiratory system 13 | 17,483
Skin and soft tissues 13 | 18,114
Urinary Tract 13 | 18,443

Target Family

Enzyme 11 | 4,146
Transporter 2 | 473

PathwayCommons: smpdb Pathway

Lysine Degradation 13 | 13
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..