Development Level

Tclin 2 | 602
Tbio 1 | 10,625
Tchem 1 | 1,890

Disease

Cancer 3 | 2,346
Epilepsy 3 | 346
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
Brugada Syndrome (disorder) 2 | 15
Brugada syndrome 2 | 26
Liver disease 2 | 219
Pain agnosia 2 | 99
Schizophrenia 2 | 501
ovarian cancer 2 | 8,484
psoriasis 2 | 6,685
Administration of Corneal Anesthesia 1 | 6
Adverse reaction to drug 1 | 54
Anesthesia for cesarean section 1 | 8
Atrophic 1 | 10
Autoimmune hepatitis 1 | 13
Autoimmune polyendocrine syndrome 1 | 6
Autosomal recessive spinocerebellar ataxia 10 1 | 1
Bipolar disorder in remission 1 | 19
Cardiovascular system disease 1 | 194
Chronic Obstructive Airway Disease 1 | 47
Colorectal Neoplasms 1 | 217
Congenital Pain Insensitivity 1 | 6
Cough 1 | 21
Diarrhea 1 | 155
Dysuria 1 | 24
EPISODIC PAIN SYNDROME, FAMILIAL, 2 1 | 1
Electrocardiogram: P-R interval 1 | 9
Epilepsy characterized by intractable complex partial seizures 1 | 28
Erythromelalgia 1 | 8
Exanthem 1 | 39
Familial atrial fibrillation 1 | 16
Febrile Convulsions 1 | 11
Growth Disorders 1 | 33
Heart Block 1 | 2
Heart conduction disease 1 | 65
Hemorrhoids 1 | 13
Hepatitis C 1 | 90
Hepatomegaly 1 | 10
Hereditary Sensory Autonomic Neuropathy, Type 5 1 | 5
Human immunodeficiency virus infectious disease 1 | 92
Hyperalgesia 1 | 71
Infestation by Phthirus pubis 1 | 7
Infestation by Sarcoptes scabiei var hominis 1 | 7
Itching of skin 1 | 19
Leber congenital amaurosis 1 | 72
Lennox-Gastaut syndrome 1 | 34
Life-Threatening Ventricular Tachycardia 1 | 15
Liver Cirrhosis, Experimental 1 | 108
Liver Neoplasms, Experimental 1 | 48
Liver diseases 1 | 66
Local Anesthesia for Endotracheal Intubation 1 | 6
Local Anesthesia for Ophthalmologic Procedure 1 | 7
Local Anesthesia for Urethral Pain 1 | 6
Local anesthesia 1 | 40
Local anesthetic intrathecal block 1 | 7
Localization-related epilepsy 1 | 13
Lung Injury 1 | 20
Lung Neoplasms 1 | 171
Major Nerve Block for Surgery 1 | 8
Mammary Neoplasms 1 | 410
Methemoglobinemia 1 | 17
Minor Skin Wound Pain 1 | 12
Motor cortex epilepsy 1 | 10
Mouth Irritation 1 | 12
Neural Tube Defects 1 | 27
Neuralgia 1 | 16
Neutropenia 1 | 78
PAROXYSMAL EXTREME PAIN DISORDER 1 | 3
Parkinsonism 1 | 19
Partial seizure 1 | 15
Pediculosis capitis 1 | 7
Porphyria cutanea tarda 1 | 12
Postherpetic neuralgia 1 | 12
Premature ejaculation 1 | 16
Prevent Minor Bacterial Skin Infection 1 | 10
Primary Erythermalgia 1 | 3
Pruritus ani 1 | 14
Regional Anesthesia for Labor Pain 1 | 9
Regional Anesthesia for Ophthalmologic Surgery 1 | 6
Regional Anesthesia for Postoperative Pain 1 | 9
Regional Anesthesia for Surgery 1 | 9
Sexual dysfunction 1 | 10
Simple partial seizure 1 | 26
Skin irritation 1 | 12
Sore throat symptom 1 | 12
Spasticity 1 | 26
Splenomegaly 1 | 7
Squamous cell carcinoma 1 | 94
Sudden infant death syndrome 1 | 33
Suppression of the Gag Reflex 1 | 12
Tinea Infections 1 | 10
Tinea corporis 1 | 25
Tonic-clonic epilepsy 1 | 47
Tonic-clonic seizure 1 | 11
Torsades de Pointes 1 | 5
Urethritis 1 | 10
Urinary Tract Irritation 1 | 24
Ventricular Fibrillation 1 | 10
Ventricular arrhythmia 1 | 14

Tissue

Blood and immune system 4 | 17,995
Cardiovascular System 4 | 17,958
Digestive Tract 4 | 18,473
Endocrine System 4 | 18,512
Female tissues 4 | 18,647
Male tissues 4 | 17,969
Nervous System 4 | 18,561
Skin and soft tissues 4 | 18,115
Urinary Tract 4 | 18,444
Liver and Pancreas 3 | 18,136
Respiratory system 3 | 17,484

Target Family

Ion Channel 2 | 341
Enzyme 1 | 4,146
Non-IDG 1 | 11,971

PathwayCommons: smpdb Pathway

Lidocaine (Local Anaesthetic) ... 4 | 4
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.10712 1336.5 120
Sodium channel subunit beta-1 SCN1B Tbio Ion Channel -1.68118 43.5 133
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.62253 4494.0 323
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.30248 2022.5 420