Development Level

Tclin 2 | 602
Tbio 1 | 10,625
Tchem 1 | 1,890

Disease

Cancer 3 | 2,346
Epilepsy 3 | 346
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
Brugada Syndrome (disorder) 2 | 15
Brugada syndrome 2 | 26
Liver disease 2 | 219
Pain agnosia 2 | 99
Schizophrenia 2 | 503
ovarian cancer 2 | 8,491
psoriasis 2 | 6,685
Administration of Corneal Anesthesia 1 | 6
Adverse reaction to drug 1 | 54
Anesthesia for cesarean section 1 | 8
Atrophic 1 | 10
Autoimmune hepatitis 1 | 13
Autoimmune polyendocrine syndrome 1 | 6
Autosomal recessive spinocerebellar ataxia 10 1 | 2
Bipolar disorder in remission 1 | 19
Cardiac arrhythmia 1 | 26
Chronic Obstructive Airway Disease 1 | 47
Colorectal Neoplasms 1 | 217
Cough 1 | 21
Diarrhea 1 | 155
Dysuria 1 | 24
Electrocardiogram: P-R interval 1 | 9
Epilepsy characterized by intractable complex partial seizures 1 | 28
Epileptic Encephalopathy, Early Infantile, 6 1 | 8
Erythromelalgia 1 | 8
Exanthem 1 | 39
Familial progressive cardiac conduction defect 1 | 4
Febrile Convulsions 1 | 11
Growth Disorders 1 | 33
Heart Block 1 | 2
Hemorrhoids 1 | 13
Hepatitis C 1 | 90
Hepatomegaly 1 | 10
Hereditary Sensory Autonomic Neuropathy, Type 5 1 | 5
Human immunodeficiency virus infection 1 | 6
Human immunodeficiency virus infectious disease 1 | 129
Hyperalgesia 1 | 71
Infestation by Phthirus pubis 1 | 7
Infestation by Sarcoptes scabiei var hominis 1 | 7
Itching of skin 1 | 19
Leber congenital amaurosis 1 | 72
Lennox-Gastaut syndrome 1 | 34
Life-Threatening Ventricular Tachycardia 1 | 15
Liver Cirrhosis, Experimental 1 | 108
Liver Neoplasms, Experimental 1 | 48
Liver diseases 1 | 66
Local Anesthesia for Endotracheal Intubation 1 | 6
Local Anesthesia for Ophthalmologic Procedure 1 | 7
Local Anesthesia for Urethral Pain 1 | 6
Local anesthesia 1 | 40
Local anesthetic intrathecal block 1 | 7
Localization-related epilepsy 1 | 13
Lung Injury 1 | 20
Lung Neoplasms 1 | 171
Major Nerve Block for Surgery 1 | 8
Mammary Neoplasms 1 | 410
Methemoglobinemia 1 | 17
Minor Skin Wound Pain 1 | 12
Motor cortex epilepsy 1 | 10
Mouth Irritation 1 | 12
Neural Tube Defects 1 | 31
Neuralgia 1 | 16
Neutropenia 1 | 78
PAROXYSMAL EXTREME PAIN DISORDER 1 | 3
Parkinsonism 1 | 19
Partial seizure 1 | 15
Pediculosis capitis 1 | 7
Porphyria cutanea tarda 1 | 12
Postherpetic neuralgia 1 | 12
Premature ejaculation 1 | 16
Prevent Minor Bacterial Skin Infection 1 | 10
Primary Erythermalgia 1 | 3
Pruritus ani 1 | 14
Regional Anesthesia for Labor Pain 1 | 9
Regional Anesthesia for Ophthalmologic Surgery 1 | 6
Regional Anesthesia for Postoperative Pain 1 | 9
Regional Anesthesia for Surgery 1 | 9
Seizures, Febrile 1 | 5
Sexual dysfunction 1 | 10
Simple partial seizure 1 | 26
Skin irritation 1 | 12
Sore throat symptom 1 | 12
Spasticity 1 | 26
Splenomegaly 1 | 7
Squamous cell carcinoma 1 | 96
Sudden infant death syndrome 1 | 34
Suppression of the Gag Reflex 1 | 12
Tinea Infections 1 | 10
Tinea corporis 1 | 25
Tonic-clonic epilepsy 1 | 47
Tonic-clonic seizure 1 | 11
Torsades de Pointes 1 | 5
Urethritis 1 | 10
Urinary Tract Irritation 1 | 24
Ventricular Fibrillation 1 | 10
Ventricular arrhythmia 1 | 14

Tissue

Blood and immune system 4 | 17,994
Cardiovascular System 4 | 17,957
Digestive Tract 4 | 18,472
Endocrine System 4 | 18,511
Female tissues 4 | 18,646
Male tissues 4 | 17,968
Nervous System 4 | 18,560
Skin and soft tissues 4 | 18,114
Urinary Tract 4 | 18,443
Liver and Pancreas 3 | 18,135
Respiratory system 3 | 17,483

Target Family

Ion Channel 2 | 341
Enzyme 1 | 4,146
Non-IDG 1 | 11,969

PathwayCommons: smpdb Pathway

Lidocaine (Local Anaesthetic) ... 4 | 4
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.31421 2022.5 420
Sodium channel subunit beta-1 SCN1B Tbio Ion Channel -1.77061 43.5 133
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.63616 4494.0 323
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.14144 1336.5 120