Development Level

Tbio 5 | 10,625
Tchem 2 | 1,890
Tdark 1 | 7,003

IMPC Term

abnormal glucose homeostasis 1 | 5
abnormal tail movements 1 | 12
cardiovascular system phenotyp... 1 | 35
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
preweaning lethality, complete... 1 | 633

Disease

psoriasis 5 | 6,685
Breast cancer 3 | 3,099
Hyperinsulinism 3 | 63
Hypoglycemia 3 | 81
Polycystic Ovary Syndrome 3 | 335
adult high grade glioma 3 | 2,148
atypical teratoid / rhabdoid tumor 3 | 4,369
diabetes mellitus 3 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung carcinoma 3 | 2,844
ovarian cancer 3 | 8,492
pancreatic cancer 3 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Diabetes Mellitus, Experimental 2 | 106
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Epilepsy 2 | 346
Fatty Liver 2 | 48
Hyperglycemia 2 | 120
Intellectual disability 2 | 573
Metabolic syndrome X 2 | 155
Multiple myeloma 2 | 1,328
Obesity 2 | 616
Pick disease 2 | 1,893
colon cancer 2 | 1,475
glioblastoma 2 | 5,572
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung adenocarcinoma 2 | 2,714
medulloblastoma, large-cell 2 | 6,234
non-small cell lung cancer 2 | 2,798
osteosarcoma 2 | 7,933
primary pancreatic ductal adenocarcinoma 2 | 1,271
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 267
Alzheimer's disease 1 | 644
Amyotrophic Lateral Sclerosis 1 | 432
Autosomal recessive non-syndromic intellectual disability 1 | 8
Cardiomyopathy 1 | 110
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Down syndrome 1 | 548
Drug-Induced Liver Injury 1 | 118
Duchenne muscular dystrophy 1 | 602
Early infantile epileptic encephalopathy with suppression bursts 1 | 18
Early myoclonic encephalopathy 1 | 9
Elephantiasis 1 | 3
Epidemic typhus 1 | 6
Epileptic encephalopathy, early infantile, 3 1 | 1
Familial hyperinsulinemic hypoglycemia 6 1 | 1
Fanconi syndrome 1 | 14
Fanconi-Bickel syndrome 1 | 1
Fetal Growth Retardation 1 | 9
Filariasis 1 | 21
Galactosemia 1 | 20
Glycogen storage disease 1 | 37
Hepatitis 1 | 61
Hepatitis B 1 | 103
Hyperammonemia 1 | 5
Hyperinsulinemic hypoglycemia 1 | 17
Hyperinsulinemic hypoglycemia, familial, 6 1 | 1
Insulin Resistance 1 | 50
Insulinoma 1 | 20
Lipid metabolism disorder 1 | 102
Lipodystrophy 1 | 32
Liver Cirrhosis, Experimental 1 | 108
Liver carcinoma 1 | 217
Liver disease 1 | 219
Liver diseases 1 | 66
Lymphangitis 1 | 5
Mammary Neoplasms 1 | 410
Microcephaly 1 | 149
Pulmonary hypertension 1 | 52
Reperfusion Injury 1 | 84
Rickets 1 | 42
Serine deficiency 1 | 9
Spastic tetraplegia, thin corpus callosum, and progressive microcephaly 1 | 1
Tricuspid valve insufficiency 1 | 11
Type 2 diabetes mellitus 1 | 192
Vitelliform macular dystrophy 1 | 14
X-linked cerebral adrenoleukodystrophy 1 | 115
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
astrocytoma 1 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
chronic lymphosyte leukemia 1 | 232
cystic fibrosis 1 | 1,670
ductal carcinoma in situ 1 | 1,745
interstitial cystitis 1 | 2,299
invasive ductal carcinoma 1 | 2,950
maturity-onset diabetes of the young 1 | 30
nephrosclerosis 1 | 329
non-inflammatory breast cancer 1 | 208
oligodendroglioma 1 | 2,849
pilocytic astrocytoma 1 | 3,086
primitive neuroectodermal tumor 1 | 3,031
tuberculosis 1 | 1,563
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 8 | 17,995
Cardiovascular System 8 | 17,958
Digestive Tract 8 | 18,473
Endocrine System 8 | 18,512
Female tissues 8 | 18,647
Liver and Pancreas 8 | 18,136
Male tissues 8 | 17,969
Nervous System 8 | 18,561
Skin and soft tissues 8 | 18,115
Urinary Tract 8 | 18,444
Respiratory system 7 | 17,484

Target Family

Transporter 5 | 473
Enzyme 3 | 4,146

PathwayCommons: smpdb Pathway

Glucose-Alanine Cycle 8 | 8
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.31334 2066.8 474
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.37706 245.3 134
Alanine aminotransferase 1 GPT Tbio Enzyme -2.45025 265.2 188
Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 Tchem Transporter -2.78795 575.0 235
Sodium-coupled neutral amino acid transporter 4 SLC38A4 Tbio Transporter -1.67516 46.8 25
Mitochondrial glutamate carrier 1 SLC25A22 Tdark Transporter -0.79067 6.67 48
Alanine aminotransferase 2 GPT2 Tbio Enzyme -2.26049 175.9 129
Neutral amino acid transporter A SLC1A4 Tbio Transporter -1.75161 53.2 131