Development Level

Tbio 5 | 10,625
Tchem 3 | 1,890
Tclin 3 | 602

Disease

ovarian cancer 10 | 8,484
glioblastoma 6 | 5,572
psoriasis 5 | 6,685
Galactosemia 4 | 20
malignant mesothelioma 4 | 3,162
medulloblastoma, large-cell 4 | 6,234
osteosarcoma 4 | 7,933
Glycogen storage disease 3 | 37
Neuropathy 3 | 210
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
breast carcinoma 3 | 1,614
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
invasive ductal carcinoma 3 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Breast cancer 2 | 3,094
Cancer 2 | 2,346
Cardiomyopathy 2 | 110
Cataract 2 | 104
Congenital disorder of glycosylation 2 | 53
Fabry disease 2 | 9
Galactosemias 2 | 3
Gaucher's disease 2 | 24
Hyperglycemia 2 | 120
Kidney disease 2 | 396
Multiple myeloma 2 | 1,327
Myocardial Ischemia 2 | 169
Obesity 2 | 616
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid / rhabdoid tumor 2 | 4,369
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,665
diabetes mellitus 2 | 1,663
group 3 medulloblastoma 2 | 2,254
group 4 medulloblastoma 2 | 1,875
hepatocellular carcinoma 2 | 532
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
pancreatic cancer 2 | 2,300
tuberculosis 2 | 1,557
ulcerative colitis 2 | 2,087
Acrodermatitis enteropathica 1 | 18
Angiokeratoma 1 | 9
Apraxia 1 | 25
Bilirubin metabolic disorder 1 | 39
Campylobacteriosis 1 | 12
Carotid artery dissection 1 | 3
Celiac disease 1 | 112
Charcot-Marie-Tooth disease 1 | 74
Complications of Diabetes Mellitus 1 | 5
Congenital Disorder Of Glycosylation, Type IIID 1 | 1
Congenital disorder of glycosylation type 2D 1 | 1
Danon disease 1 | 6
Diabetes Mellitus, Experimental 1 | 106
Diabetes Mellitus, Insulin-Dependent 1 | 76
Diabetes mellitus type 2 1 | 69
Diabetic Retinopathy 1 | 53
Diabetic neuropathy 1 | 8
Diarrhea 1 | 155
Drug allergy 1 | 36
Endometrial Neoplasms 1 | 50
Esophagitis 1 | 26
Exanthem 1 | 39
Fucosidosis 1 | 10
Gangliosidosis 1 | 17
Gastroesophageal reflux disease 1 | 37
Giardiasis 1 | 10
Glucosephosphate dehydrogenase deficiency 1 | 15
Glucosylceramide beta-glucosidase deficiency 1 | 4
Glycoproteinosis 1 | 13
Gout 1 | 93
Hepatitis 1 | 61
Hepatitis B 1 | 103
Histiocytosis 1 | 12
Hyperinsulinism 1 | 63
Hypertrophic Cardiomyopathy 1 | 56
Hyperuricemia 1 | 35
Hypoglycemia 1 | 81
Hypohidrosis 1 | 13
Irritable bowel syndrome 1 | 59
Krabbe disease 1 | 11
Lactic acidosis 1 | 42
Lactose intolerance 1 | 7
Left Ventricular Hypertrophy 1 | 24
Milk allergy 1 | 3
Myopathy 1 | 128
Neurodegenerative disease 1 | 383
Neutropenia 1 | 78
Ovarian dysfunction 1 | 19
Periventricular leukomalacia 1 | 6
Phenylketonuria 1 | 18
Premature ovarian failure 1 | 64
Ptosis 1 | 42
Respiratory failure 1 | 30
Sleeping sickness 1 | 37
Tinea corporis 1 | 25
Type 1 diabetes mellitus 1 | 101
Typhoid fever 1 | 22
substance-related disorder 1 | 105

Tissue

Blood and immune system 11 | 17,995
Cardiovascular System 11 | 17,958
Digestive Tract 11 | 18,473
Endocrine System 11 | 18,512
Female tissues 11 | 18,647
Liver and Pancreas 11 | 18,136
Nervous System 11 | 18,561
Respiratory system 11 | 17,484
Skin and soft tissues 11 | 18,115
Urinary Tract 11 | 18,444
Male tissues 10 | 17,969

Target Family

Enzyme 10 | 4,146
Kinase 1 | 634

PathwayCommons: smpdb Pathway

Galactose Metabolism 11 | 11
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aldose reductase AKR1B1 Tclin Enzyme -3.24467 1851.0 302
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.28449 197.5 112
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.67373 478.5 119
Glucose-6-phosphatase G6PC Tchem Enzyme -2.93435 870.2 71
Lysosomal alpha-glucosidase GAA Tclin Enzyme -3.03573 1113.9 149
Lactase-phlorizin hydrolase LCT Tbio Enzyme -2.62818 420.2 32
Alpha-galactosidase A GLA Tclin Enzyme -2.95776 936.7 218
UTP--glucose-1-phosphate uridylyltransferase UGP2 Tbio Enzyme -2.52916 337.9 131
Hexokinase-1 HK1 Tchem Kinase -2.54887 357.5 535
UDP-glucose 4-epimerase GALE Tchem Enzyme -2.39432 251.8 165