Development Level

Tchem 3 | 1,890
Tclin 2 | 602

Disease

Cancer 5 | 2,346
Liver disease 5 | 219
Acute kidney injury 3 | 65
Adverse reaction to drug 3 | 54
Epilepsy 3 | 346
Schizophrenia 3 | 501
diabetes mellitus 3 | 1,663
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
psoriasis 3 | 6,685
Atrial Fibrillation 2 | 110
Autoimmune hepatitis 2 | 13
Coronary artery disease 2 | 240
Drug-Induced Liver Injury 2 | 118
Hepatitis C 2 | 90
Major Depressive Disorder 2 | 106
Mammary Neoplasms 2 | 410
Nephritis, Interstitial 2 | 10
Pain agnosia 2 | 99
Prostatic Neoplasms 2 | 471
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
ovarian cancer 2 | 8,484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
Alzheimer's disease 1 | 644
Amphetamine-Related Disorders 1 | 74
Aspergillosis 1 | 23
Atrophic 1 | 10
Autoimmune polyendocrine syndrome 1 | 6
Basal Ganglia Diseases 1 | 12
Bradycardia 1 | 24
Brain Neoplasms 1 | 23
Cardiomyopathies 1 | 90
Cardiovascular Diseases 1 | 50
Cardiovascular system disease 1 | 194
Cardioversion of Atrial Fibrillation 1 | 9
Cerebrovascular disease 1 | 231
Cholestasis 1 | 93
Chronic Obstructive Airway Disease 1 | 47
Colorectal Neoplasms 1 | 217
Comatose 1 | 4
Constipation 1 | 43
Delusional disorder 1 | 10
Dementia 1 | 129
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Diarrhea 1 | 155
Drug allergy 1 | 36
Dystonia 1 | 77
Esophageal candidiasis 1 | 3
Esophagitis 1 | 26
Exanthem 1 | 39
Gastritis 1 | 44
Gastroesophageal reflux disease 1 | 37
Growth Disorders 1 | 33
Hemorrhage 1 | 18
Hepatitis D 1 | 10
Hepatomegaly 1 | 10
Human immunodeficiency virus infectious disease 1 | 92
Hypertension 1 | 287
Kidney Failure, Chronic 1 | 45
Kidney disease 1 | 396
Leber congenital amaurosis 1 | 72
Life-Threatening Ventricular Tachycardia 1 | 15
Liver Cirrhosis, Experimental 1 | 108
Liver Neoplasms, Experimental 1 | 48
Liver diseases 1 | 66
Lung Injury 1 | 20
Lung Neoplasms 1 | 171
Malaria 1 | 140
Manganese Poisoning 1 | 11
Metastatic Prostate Carcinoma 1 | 18
Methemoglobinemia 1 | 17
Muscle Rigidity 1 | 5
Neural Tube Defects 1 | 27
Neuroleptic malignant syndrome 1 | 8
Neutropenia 1 | 78
Occupational Diseases 1 | 8
Parkinson Disease 1 | 102
Parkinson's disease 1 | 364
Peptic Ulcer Hemorrhage 1 | 2
Peptic ulcer disease 1 | 11
Peripheral Neuropathy 1 | 303
Porphyria cutanea tarda 1 | 12
Prenatal Exposure Delayed Effects 1 | 9
Pseudobulbar affect 1 | 5
Schizoaffective disorder 1 | 33
Sexual dysfunction 1 | 10
Squamous cell carcinoma 1 | 94
Substance-Related Disorders 1 | 114
Thrombosis 1 | 42
Tonic-clonic epilepsy 1 | 47
Torsades de Pointes 1 | 5
Toxic encephalopathy 1 | 131
Vascular disease 1 | 281
Weight Gain 1 | 87
active Crohn's disease 1 | 918
adrenocortical adenoma 1 | 134
nervous system disorder 1 | 53
obsessive-compulsive disorder 1 | 34
substance-related disorder 1 | 105
tuberculosis 1 | 1,557

Tissue

Blood and immune system 5 | 17,995
Cardiovascular System 5 | 17,958
Digestive Tract 5 | 18,473
Endocrine System 5 | 18,512
Female tissues 5 | 18,647
Liver and Pancreas 5 | 18,136
Male tissues 5 | 17,969
Nervous System 5 | 18,561
Respiratory system 5 | 17,484
Skin and soft tissues 5 | 18,115
Urinary Tract 5 | 18,444

Target Family

Non-IDG 3 | 11,971
Enzyme 2 | 4,146

PathwayCommons: smpdb Pathway

Doxepin Metabolism Pathway 5 | 5
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 2C19 CYP2C19 Tchem Non-IDG -3.17457 1627.4 145
Cytochrome P450 2D6 CYP2D6 Tclin Enzyme -3.50005 3352.9 382
Cytochrome P450 2C9 CYP2C9 Tchem Non-IDG -3.17625 1560.3 155
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.62253 4494.0 323
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.30248 2022.5 420