Development Level

Tchem 5 | 1,890
Tclin 3 | 602
Tbio 1 | 10,625

Disease

Cancer 7 | 2,346
medulloblastoma, large-cell 6 | 6,234
Liver disease 5 | 219
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
psoriasis 5 | 6,685
Coronary artery disease 4 | 240
Drug-Induced Liver Injury 4 | 118
Epilepsy 4 | 346
Prostatic Neoplasms 4 | 471
diabetes mellitus 4 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung cancer 4 | 4,466
ovarian cancer 4 | 8,484
tuberculosis 4 | 1,557
Acute coronary syndrome 3 | 37
Adverse reaction to drug 3 | 54
Atrial Fibrillation 3 | 110
Cerebrovascular disease 3 | 231
Hypertension 3 | 287
Neurotoxicity Syndromes 3 | 26
Schizophrenia 3 | 501
Thrombosis 3 | 42
adrenocortical carcinoma 3 | 1,427
atypical teratoid / rhabdoid tumor 3 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung carcinoma 3 | 2,844
non-small cell lung cancer 3 | 2,798
osteosarcoma 3 | 7,933
pancreatic cancer 3 | 2,300
Acute kidney injury 2 | 65
Brain Neoplasms 2 | 23
Breast cancer 2 | 3,094
Cardiovascular Diseases 2 | 50
Cerebrovascular Occlusion 2 | 5
Colorectal Neoplasms 2 | 217
Drug Metabolism, Poor, CYP2C19-Related 2 | 2
Hematologic Neoplasms 2 | 4
Hemorrhage 2 | 18
Human immunodeficiency virus infection 2 | 6
Kidney Failure, Chronic 2 | 45
Kidney disease 2 | 396
Liver Cirrhosis, Experimental 2 | 108
Lung Neoplasms 2 | 171
Mammary Neoplasms 2 | 410
Neutropenia 2 | 78
Percutaneous coronary intervention 2 | 10
Peripheral Neuropathy 2 | 303
Porphyria cutanea tarda 2 | 12
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 42
Prevention of Cerebral Thrombosis 2 | 29
Rheumatoid Arthritis 2 | 1,160
Subacute Stent Thrombosis Prevention 2 | 5
active Crohn's disease 2 | 918
adult high grade glioma 2 | 2,148
cutaneous lupus erythematosus 2 | 1,056
glioblastoma 2 | 5,572
lung adenocarcinoma 2 | 2,713
nervous system disorder 2 | 53
non primary Sjogren syndrome sicca 2 | 840
oligodendroglioma 2 | 2,849
pituitary cancer 2 | 1,972
substance-related disorder 2 | 105
ulcerative colitis 2 | 2,087
Aspergillosis 1 | 23
Autoimmune hepatitis 1 | 13
Carcinoma of female breast 1 | 20
Chronic Obstructive Airway Disease 1 | 47
Coronary Artery Vasospasm 1 | 6
Diabetic Retinopathy 1 | 53
Diarrhea 1 | 155
Diffuse large B-cell lymphoma 1 | 41
Esophageal candidiasis 1 | 3
Esophagitis 1 | 26
Gastritis 1 | 44
Gestational trophoblastic neoplasia 1 | 14
Hepatomegaly 1 | 10
Hodgkin's disease 1 | 18
Human immunodeficiency virus infectious disease 1 | 92
Hypertensive disorder 1 | 58
Hyperthyroidism 1 | 50
Kaposi's sarcoma 1 | 20
Langerhans cell histiocytosis, disseminated 1 | 10
Liver Neoplasms, Experimental 1 | 48
Lung Injury 1 | 20
Lupus Erythematosus, Systemic 1 | 73
Malignant tumor of testis 1 | 11
Marijuana Abuse 1 | 8
Metastatic Breast Carcinoma 1 | 21
Metastatic Prostate Carcinoma 1 | 18
Methemoglobinemia 1 | 17
Mycosis fungoides 1 | 28
Myocardial Infarction 1 | 126
Neuroectodermal Tumor, Primitive 1 | 8
Non-Hodgkin's lymphoma 1 | 22
Paroxysmal supraventricular tachycardia 1 | 11
Prevention of Paroxysmal Supraventricular Tachycardia 1 | 4
Prinzmetal angina 1 | 6
Squamous cell carcinoma of the head and neck 1 | 24
Transient cerebral ischemia 1 | 14

Tissue

Blood and immune system 9 | 17,995
Cardiovascular System 9 | 17,958
Digestive Tract 9 | 18,473
Endocrine System 9 | 18,512
Female tissues 9 | 18,647
Liver and Pancreas 9 | 18,136
Male tissues 9 | 17,969
Nervous System 9 | 18,561
Respiratory system 9 | 17,484
Skin and soft tissues 9 | 18,115
Urinary Tract 9 | 18,444

Target Family

Non-IDG 4 | 11,971
Enzyme 3 | 4,146
GPCR 1 | 406
Transporter 1 | 473

PathwayCommons: smpdb Pathway

Clopidogrel Metabolism Pathway 9 | 9
Phenytoin (Antiarrhythmic) Act... 79 | 79
Lidocaine (Antiarrhythmic) Act... 61 | 61
Carvedilol Action Pathway 60 | 60
Labetalol Action Pathway 60 | 60
Muscle/Heart Contraction 60 | 60
Acebutolol Action Pathway 59 | 59
Alprenolol Action Pathway 59 | 59
Amiodarone Action Pathway 59 | 59
Amlodipine Action Pathway 59 | 59
Arbutamine Action Pathway 59 | 59
Atenolol Action Pathway 59 | 59
Betaxolol Action Pathway 59 | 59
Bevantolol Action Pathway 59 | 59
Bisoprolol Action Pathway 59 | 59
Bopindolol Action Pathway 59 | 59
Bupranolol Action Pathway 59 | 59
Carteolol Action Pathway 59 | 59
Diltiazem Action Pathway 59 | 59
Disopyramide Action Pathway 59 | 59
Dobutamine Action Pathway 59 | 59
Epinephrine Action Pathway 59 | 59
Esmolol Action Pathway 59 | 59
Felodipine Action Pathway 59 | 59
Flecainide Action Pathway 59 | 59
Fosphenytoin (Antiarrhythmic) ... 59 | 59
Ibutilide Action Pathway 59 | 59
Isoprenaline Action Pathway 59 | 59
Isradipine Action Pathway 59 | 59
Levobunolol Action Pathway 59 | 59
Metipranolol Action Pathway 59 | 59
Metoprolol Action Pathway 59 | 59
Mexiletine Action Pathway 59 | 59
Nadolol Action Pathway 59 | 59
Nebivolol Action Pathway 59 | 59
Nifedipine Action Pathway 59 | 59
Nimodipine Action Pathway 59 | 59
Nisoldipine Action Pathway 59 | 59
Nitrendipine Action Pathway 59 | 59
Oxprenolol Action Pathway 59 | 59
Penbutolol Action Pathway 59 | 59
Pindolol Action Pathway 59 | 59
Practolol Action Pathway 59 | 59
Procainamide (Antiarrhythmic) ... 59 | 59
Propranolol Action Pathway 59 | 59
Quinidine Action Pathway 59 | 59
Sotalol Action Pathway 59 | 59
Timolol Action Pathway 59 | 59
Tocainide Action Pathway 59 | 59
Verapamil Action Pathway 59 | 59
Azathioprine Action Pathway 47 | 47
Ibuprofen Action Pathway 47 | 47
Mercaptopurine Action Pathway 47 | 47
Thioguanine Action Pathway 47 | 47
Warburg Effect 45 | 45
Intracellular Signalling Throu... 38 | 38
AICA-Ribosiduria 37 | 37
Adenine phosphoribosyltransfer... 37 | 37
Adenosine Deaminase Deficiency 37 | 37
Adenylosuccinate Lyase Deficie... 37 | 37
Gout or Kelley-Seegmiller Synd... 37 | 37
Intracellular Signalling Throu... 37 | 37
Lesch-Nyhan Syndrome (LNS) 37 | 37
Mitochondrial DNA depletion sy... 37 | 37
Molybdenum Cofactor Deficiency 37 | 37
Myoadenylate deaminase deficie... 37 | 37
Purine Metabolism 37 | 37
Purine Nucleoside Phosphorylas... 37 | 37
Xanthine Dehydrogenase Deficie... 37 | 37
Xanthinuria type I 37 | 37
Xanthinuria type II 37 | 37
Fc Epsilon Receptor I Signalin... 36 | 36
Morphine Action Pathway 35 | 35
Retinol Metabolism 35 | 35
Vitamin A Deficiency 35 | 35
Celecoxib Action Pathway 34 | 34
Eplerenone Action Pathway 33 | 33
Spironolactone Action Pathway 33 | 33
Amiloride Action Pathway 32 | 32
Bendroflumethiazide Action Pat... 32 | 32
Blue diaper syndrome 32 | 32
Bumetanide Action Pathway 32 | 32
Chlorothiazide Action Pathway 32 | 32
Chlorthalidone Action Pathway 32 | 32
Cyclothiazide Action Pathway 32 | 32
Cystinuria 32 | 32
Ethacrynic Acid Action Pathway 32 | 32
Furosemide Action Pathway 32 | 32
Glucose Transporter Defect (SG... 32 | 32
Hartnup Disorder 32 | 32
Hydrochlorothiazide Action Pat... 32 | 32
Hydroflumethiazide Action Path... 32 | 32
Iminoglycinuria 32 | 32
Indapamide Action Pathway 32 | 32
Kidney Function 32 | 32
Lysinuric Protein Intolerance 32 | 32
Lysinuric protein intolerance ... 32 | 32
Methyclothiazide Action Pathwa... 32 | 32
Metolazone Action Pathway 32 | 32
Polythiazide Action Pathway 32 | 32
Quinethazone Action Pathway 32 | 32

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serum paraoxonase/arylesterase 1 PON1 Tbio Enzyme -3.35039 2495.3 346
Cytochrome P450 2C19 CYP2C19 Tchem Non-IDG -3.17457 1627.4 145
P2Y purinoceptor 12 P2RY12 Tclin GPCR -3.12953 1370.8 127
Cytochrome P450 2C9 CYP2C9 Tchem Non-IDG -3.17625 1560.3 155
Multidrug resistance protein 1 ABCB1 Tchem Transporter -3.56027 3760.3 500
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.62253 4494.0 323
Cytochrome P450 3A5 CYP3A5 Tclin Enzyme -2.77536 609.8 100
Cytochrome P450 2B6 CYP2B6 Tchem Non-IDG -3.69631 5025.3 171
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.30248 2022.5 420