Development Level

Tchem 18 | 1,598
Tbio 16 | 11,445
Tclin 8 | 613

IMPC Phenotype

abnormal seminal vesicle morph... 3 | 114
enlarged heart 3 | 210
abnormal behavior 2 | 298
preweaning lethality, complete... 2 | 979
abnormal colon morphology 1 | 3
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal ileum morphology 1 | 2
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
increased circulating alkaline... 1 | 122
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
prolonged ST segment 1 | 36
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 37 | 11,493
Cancer 27 | 2,499
osteosarcoma 26 | 7,950
ovarian cancer 23 | 8,520
glioblastoma 19 | 5,792
invasive ductal carcinoma 19 | 2,951
Breast cancer 16 | 3,578
interstitial cystitis 16 | 2,312
lung cancer 16 | 4,740
lung carcinoma 16 | 2,843
malignant mesothelioma 16 | 3,232
psoriasis 16 | 6,694
Autosomal recessive predisposition 15 | 1,442
pancreatic cancer 15 | 2,398
ulcerative colitis 15 | 1,819
tuberculosis 14 | 2,010
Astrocytoma, Pilocytic 13 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
medulloblastoma, large-cell 13 | 6,241
non-small cell lung cancer 13 | 2,890
Neoplasm Invasiveness 12 | 161
Schizophrenia 12 | 1,160
atypical teratoid / rhabdoid tumor 12 | 5,112
diabetes mellitus 12 | 1,728
Atherosclerosis 11 | 291
Kidney cancer 11 | 2,613
cutaneous lupus erythematosus 11 | 1,057
cystic fibrosis 11 | 1,696
lung adenocarcinoma 11 | 2,716
Arthritis 10 | 290
Kidney disease 10 | 430
Liver Cirrhosis, Experimental 10 | 769
adult high grade glioma 10 | 3,801
gastric carcinoma 10 | 807
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
primary pancreatic ductal adenocarcinoma 10 | 1,109
Atopic dermatitis 9 | 952
Coronary artery disease 9 | 268
colon cancer 9 | 1,478
ductal carcinoma in situ 9 | 1,745
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
Cerebrovascular disease 8 | 238
Neoplasm Metastasis 8 | 168
Prostatic Neoplasms 8 | 495
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
mucosa-associated lymphoid tissue lymphoma 8 | 484
periodontitis 8 | 293
Alzheimer's disease 7 | 658
Hypersensitivity reaction type II disease 7 | 253
Hypertensive disease 7 | 292
Liver disease 7 | 237
Lung disease 7 | 142
adrenocortical carcinoma 7 | 1,428
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
oligodendroglioma 7 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
Carcinoma, Squamous Cell 6 | 110
Heart disease 6 | 306
Hypertension 6 | 396
Multiple Sclerosis 6 | 540
Osteoporosis 6 | 363
Rheumatoid arthritis 6 | 1,191
Spontaneous abortion 6 | 113
Squamous cell carcinoma 6 | 129
Stomach Neoplasms 6 | 300
Thrombophilia 6 | 38
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
nasopharyngeal carcinoma 6 | 1,058
Asthma 5 | 385
Breast Neoplasms 5 | 445
Calcinosis 5 | 70
Carcinoma, Hepatocellular 5 | 228
Cerebral Hemorrhage 5 | 42
Endometriosis 5 | 540
Epistaxis 5 | 43
Inflammatory bowel disease 5 | 151
Liver carcinoma 5 | 240
Mammary Neoplasms 5 | 425
Myocardial Infarction 5 | 151
Pancreatic Neoplasms 5 | 85
Pancreatitis 5 | 123
Vascular disease 5 | 319
Venous Thrombosis 5 | 47
esophageal adenocarcinoma 5 | 737
inflammatory breast cancer 5 | 286
pediatric high grade glioma 5 | 1,064
sarcoidosis 5 | 370
Bipolar Disorder 4 | 666
Colonic Neoplasms 4 | 142
Liver Cirrhosis 4 | 181
Major Depressive Disorder 4 | 301
Melanoma 4 | 711
Pancreatic Neoplasm 4 | 85
Reperfusion Injury 4 | 86
Unipolar Depression 4 | 250
acute myeloid leukemia 4 | 783

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Male tissues 42 | 17,142
Respiratory system 42 | 16,393
Urinary Tract 42 | 16,678
Blood and immune system 41 | 16,909
Liver and Pancreas 41 | 16,750
Skin and soft tissues 41 | 17,230
Nervous System 37 | 16,725
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 13 | 4,145
GPCR 3 | 408
Kinase 3 | 634
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-formyl peptide receptor 3 FPR3 Tchem GPCR -1.41613 24.4 247
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Integrin alpha-M ITGAM Tbio Non-IDG -3.63427 3939.5 2165
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Macrophage metalloelastase MMP12 Tchem Enzyme 0.00000 447
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384
Neutrophil elastase ELANE Tclin Enzyme -3.61753 3958.4 411
Integrin alpha-5 ITGA5 Tbio Non-IDG -2.29130 169.1 826
fMet-Leu-Phe receptor FPR1 Tchem GPCR -2.42752 255.1 277
Phosphatidylinositol-glycan-specific phospholipase D GPLD1 Tbio Enzyme -2.08209 126.8 222