Development Level

Tchem 20 | 1,598
Tbio 19 | 11,445
Tclin 3 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating LDL chol... 1 | 13
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
polycystic kidney 1 | 15
premature death 1 | 5
short tibia 1 | 97

Disease

Carcinoma 31 | 11,493
ovarian cancer 25 | 8,520
osteosarcoma 24 | 7,950
Cancer 21 | 2,499
medulloblastoma, large-cell 21 | 6,241
ependymoma 20 | 4,679
atypical teratoid / rhabdoid tumor 19 | 5,112
glioblastoma 19 | 5,792
psoriasis 18 | 6,694
Breast cancer 16 | 3,578
adult high grade glioma 14 | 3,801
lung cancer 14 | 4,740
Kidney cancer 12 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
oligodendroglioma 11 | 2,850
subependymal giant cell astrocytoma 11 | 2,287
Alzheimer's disease 10 | 658
Schizophrenia 10 | 1,160
diabetes mellitus 10 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Bipolar Disorder 9 | 666
Epilepsy 9 | 792
breast carcinoma 9 | 1,638
pancreatic cancer 9 | 2,398
group 3 medulloblastoma 8 | 4,104
lung adenocarcinoma 8 | 2,716
Astrocytoma, Pilocytic 7 | 3,081
Carcinoma, Hepatocellular 7 | 228
Liver carcinoma 7 | 240
Multiple myeloma 7 | 1,332
Neoplasm Metastasis 7 | 168
Parkinson's disease 7 | 392
Pick disease 7 | 1,894
Prostatic Neoplasms 7 | 495
Vascular disease 7 | 319
acute quadriplegic myopathy 7 | 1,158
malignant mesothelioma 7 | 3,232
pediatric high grade glioma 7 | 1,064
Carcinoma, Squamous Cell 6 | 110
Dementia 6 | 175
Hypertensive disease 6 | 292
Peutz-Jeghers syndrome 6 | 21
Squamous cell carcinoma 6 | 129
Toxic encephalopathy 6 | 141
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
primitive neuroectodermal tumor 6 | 3,035
Adenocarcinoma 5 | 122
Depressive disorder 5 | 409
Liver Cirrhosis, Experimental 5 | 769
Major Depressive Disorder 5 | 301
Mood Disorders 5 | 184
Mouth Neoplasms 5 | 55
Neurodegenerative disease 5 | 414
Pancreatic Neoplasm 5 | 85
Pancreatic Neoplasms 5 | 85
Renal Cell Carcinoma 5 | 214
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
juvenile dermatomyositis 5 | 1,187
non-small cell lung cancer 5 | 2,890
pituitary cancer 5 | 1,972
Abdominal Pain 4 | 98
Adenocarcinoma of lung (disorder) 4 | 60
Adenoma 4 | 167
Alzheimer Disease 4 | 83
Autistic Disorder 4 | 364
Breast Neoplasms 4 | 445
Carcinoma, Renal Cell 4 | 124
Cognition Disorders 4 | 32
Down syndrome 4 | 499
Hypertension 4 | 396
Intellectual disability 4 | 1,016
Isolated cases 4 | 72
Lung Neoplasms 4 | 232
Lymphangioleiomyomatosis 4 | 16
Mammary Neoplasms 4 | 425
Myocardial Infarction 4 | 151
Obesity 4 | 678
Osteoarthritis 4 | 184
Somatic mutation 4 | 61
Unipolar Depression 4 | 250
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Mental Depression 3 | 333
Polycystic ovary syndrome 3 | 360
adrenocortical carcinoma 3 | 1,428
hepatocellular carcinoma 3 | 547
pancreatic carcinoma 3 | 562

Tissue

Blood and immune system 43 | 16,909
Cardiovascular System 43 | 15,192
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678

Target Family

Non-IDG 20 | 12,091
Kinase 14 | 634
Transcription Factor 5 | 1,400
Enzyme 3 | 4,145
Nuclear Receptor 1 | 48

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
Serine/threonine-protein kinase SIK3 SIK3 Tchem Kinase -1.18286 18.2 0
Serine/threonine-protein kinase BRSK2 BRSK2 Tchem Kinase -1.92813 85.3 187
Serine/threonine-protein kinase SIK2 SIK2 Tchem Kinase -1.50719 36.5 233
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Serine/threonine-protein kinase BRSK1 BRSK1 Tchem Kinase -1.44039 28.9 301
Serine/threonine-protein kinase 11-interacting protein STK11IP Tdark Enzyme -0.28065 0.94 99
Microtubule-associated protein 2 MAP2 Tchem Non-IDG -3.04327 1110.6 935
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779