Development Level

Tbio 44 | 11,445
Tchem 17 | 1,598
Tclin 8 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
increased erythrocyte cell num... 2 | 39
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal snout morphology 1 | 23
abnormal somite shape 1 | 5
abnormal tooth morphology 1 | 24
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 51 | 11,493
ovarian cancer 49 | 8,520
Cancer 42 | 2,499
osteosarcoma 41 | 7,950
psoriasis 35 | 6,694
glioblastoma 29 | 5,792
lung cancer 28 | 4,740
medulloblastoma, large-cell 26 | 6,241
Breast cancer 25 | 3,578
atypical teratoid / rhabdoid tumor 22 | 5,112
Kidney cancer 20 | 2,613
Schizophrenia 20 | 1,160
group 3 medulloblastoma 20 | 4,104
diabetes mellitus 17 | 1,728
Lung Neoplasms 16 | 232
Multiple myeloma 16 | 1,332
malignant mesothelioma 16 | 3,232
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
Vascular disease 14 | 319
ependymoma 14 | 4,679
Carcinoma, Hepatocellular 13 | 228
Liver carcinoma 13 | 240
Pick disease 13 | 1,894
Prostatic Neoplasms 13 | 495
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
subependymal giant cell astrocytoma 13 | 2,287
Intellectual disability 12 | 1,016
Squamous cell carcinoma 12 | 129
Waldenstrons macroglobulinemia 12 | 765
Autosomal recessive predisposition 11 | 1,442
Dull intelligence 11 | 645
Kidney disease 11 | 430
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Neoplasm Metastasis 11 | 168
Poor school performance 11 | 645
Short stature 11 | 531
pancreatic cancer 11 | 2,398
primitive neuroectodermal tumor 11 | 3,035
tuberculosis 11 | 2,010
Adenocarcinoma 10 | 122
Carcinoma, Squamous Cell 10 | 110
Disease Models, Animal 10 | 155
Heart disease 10 | 306
Stomach Neoplasms 10 | 300
astrocytoma 10 | 1,146
Asthma 9 | 385
Cell Transformation, Neoplastic 9 | 97
Major Depressive Disorder 9 | 301
Melanoma 9 | 711
Multiple Sclerosis 9 | 540
Obesity 9 | 678
Osteoporosis 9 | 363
Rheumatoid arthritis 9 | 1,191
Small head 9 | 374
acute quadriplegic myopathy 9 | 1,158
dermatomyositis 9 | 966
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
non primary Sjogren syndrome sicca 9 | 891
pituitary cancer 9 | 1,972
Anemia 8 | 365
Astrocytoma, Pilocytic 8 | 3,081
Bipolar Disorder 8 | 666
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Hypertensive disease 8 | 292
Liver Cirrhosis 8 | 181
Liver neoplasms 8 | 130
Mental and motor retardation 8 | 608
Neoplastic Cell Transformation 8 | 89
Ovarian Neoplasms 8 | 102
Unipolar Depression 8 | 250
breast carcinoma 8 | 1,638
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
juvenile dermatomyositis 8 | 1,187
ovarian neoplasm 8 | 99
Adenoma 7 | 167
Arthritis 7 | 290
Colonic Neoplasms 7 | 142
Crohn's disease 7 | 321
Fetal Growth Retardation 7 | 189
Infant, Small for Gestational Age 7 | 176
Inflammatory bowel disease 7 | 151
Intrauterine retardation 7 | 176
Lung disease 7 | 142
Mood Disorders 7 | 184
Neoplasm Invasiveness 7 | 161
adult high grade glioma 7 | 3,801
hepatocellular carcinoma 7 | 547
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819

Tissue

Blood and immune system 70 | 16,909
Digestive Tract 70 | 17,369
Endocrine System 69 | 18,159
Female tissues 69 | 17,400
Liver and Pancreas 69 | 16,750
Male tissues 69 | 17,142
Skin and soft tissues 69 | 17,230
Cardiovascular System 68 | 15,192
Nervous System 68 | 16,725
Respiratory system 68 | 16,393
Urinary Tract 68 | 16,678

Target Family

Non-IDG 30 | 12,091
Transcription Factor 15 | 1,400
Enzyme 12 | 4,145
Kinase 9 | 634
Epigenetic 2 | 242
Nuclear Receptor 2 | 48

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Telomeric repeat-binding factor 2-interacting protein 1 TERF2IP Tchem Non-IDG -0.75509 5.75 308
Telomeric repeat-binding factor 2 TERF2 Tbio Transcription Factor -2.23836 174.6 367
Protein SMG5 SMG5 Tbio Non-IDG -1.02024 9.67 88
Paired amphipathic helix protein Sin3b SIN3B Tbio Non-IDG -1.34131 21.4 148
Interferon regulatory factor 1 IRF1 Tbio Transcription Factor -2.90315 827.7 366
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Histone deacetylase complex subunit SAP30 SAP30 Tbio Enzyme -1.22814 13.9 145
Ribosomal protein S6 kinase beta-1 RPS6KB1 Tchem Kinase -3.18361 0.00000 1818
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571