Development Level

Tbio 9 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal embryo size 1 | 220
decreased circulating bilirubi... 1 | 19
hemorrhage 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
preweaning lethality, complete... 1 | 979
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 16 | 11,493
glioblastoma 14 | 5,792
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
Breast cancer 11 | 3,578
lung carcinoma 11 | 2,843
Cancer 10 | 2,499
adult high grade glioma 10 | 3,801
atypical teratoid / rhabdoid tumor 10 | 5,112
medulloblastoma, large-cell 10 | 6,241
pancreatic cancer 10 | 2,398
ependymoma 9 | 4,679
interstitial cystitis 9 | 2,312
cystic fibrosis 8 | 1,696
invasive ductal carcinoma 8 | 2,951
Astrocytoma, Pilocytic 7 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
psoriasis 7 | 6,694
diabetes mellitus 6 | 1,728
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
primary pancreatic ductal adenocarcinoma 6 | 1,109
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
Atopic dermatitis 5 | 952
Kidney cancer 5 | 2,613
acute quadriplegic myopathy 5 | 1,158
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Duchenne muscular dystrophy 4 | 601
Hypertensive disease 4 | 292
Liver Cirrhosis 4 | 181
Multiple Sclerosis 4 | 540
active ulcerative colitis 4 | 764
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
Abortion, Spontaneous 3 | 109
Aortic Valve Insufficiency 3 | 40
Asthma 3 | 385
Becker muscular dystrophy 3 | 191
Coronary artery disease 3 | 268
Crohn's disease 3 | 321
Increase in blood pressure 3 | 119
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Neoplasm Invasiveness 3 | 161
Rheumatoid arthritis 3 | 1,191
Spontaneous abortion 3 | 113
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
limb girdle muscular dystrophy 2A 3 | 213
nephrosclerosis 3 | 333
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Arthritis, Juvenile 2 | 126
Atherosclerosis 2 | 291
Autistic Disorder 2 | 364
Byzanthine arch palate 2 | 194
Carcinoma, Hepatocellular 2 | 228
Cerebrovascular accident 2 | 63
Chest Pain 2 | 38
Crohn Disease 2 | 45
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Endometriosis 2 | 540
Gaucher disease type 1 2 | 180
Heart disease 2 | 306
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Inflammatory bowel disease 2 | 151
Juvenile arthritis 2 | 126
Liver carcinoma 2 | 240
Mesothelioma, Malignant 2 | 105
Neoplasm Metastasis 2 | 168
Stroke 2 | 33
active Crohn's disease 2 | 922
esophageal adenocarcinoma 2 | 737
fascioscapulohumeral muscular dystrophy 2 | 100
head and neck cancer 2 | 271
hereditary spastic paraplegia 2 | 318
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
sarcoidosis 2 | 370
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 13 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 137 | 137
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Integrin alpha-4 ITGA4 Tclin Non-IDG -2.53262 310.4 1312
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
Protein CYR61 CYR61 Tbio Non-IDG -2.43164 320.5 423
Mucosal addressin cell adhesion molecule 1 MADCAM1 Tbio Non-IDG -2.38746 252.3 538
Integrin beta-8 ITGB8 Tbio Non-IDG -1.47947 27.7 99
Integrin beta-7 ITGB7 Tclin Non-IDG -1.63572 38.4 374
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -2.05224 110.5 188
Syndecan-1 SDC1 Tbio Non-IDG -3.25832 1806.2 994
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413