Development Level

Tchem 26 | 1,598
Tbio 21 | 11,445
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal retina morphology 2 | 71
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased circulating fructosa... 1 | 30
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
enlarged lymph nodes 1 | 37
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased or absent threshold ... 1 | 101
male infertility 1 | 123
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 37 | 11,493
ovarian cancer 32 | 8,520
medulloblastoma, large-cell 31 | 6,241
osteosarcoma 30 | 7,950
psoriasis 29 | 6,694
glioblastoma 28 | 5,792
Cancer 26 | 2,499
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 24 | 4,679
lung cancer 24 | 4,740
adult high grade glioma 20 | 3,801
group 3 medulloblastoma 20 | 4,104
oligodendroglioma 17 | 2,850
lung adenocarcinoma 16 | 2,716
primitive neuroectodermal tumor 16 | 3,035
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 15 | 3,578
Schizophrenia 14 | 1,160
astrocytic glioma 14 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
malignant mesothelioma 13 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Kidney cancer 11 | 2,613
Pick disease 11 | 1,894
Rheumatoid arthritis 11 | 1,191
group 4 medulloblastoma 11 | 1,855
lung carcinoma 11 | 2,843
non-small cell lung cancer 11 | 2,890
subependymal giant cell astrocytoma 11 | 2,287
Bipolar Disorder 10 | 666
interstitial cystitis 10 | 2,312
tuberculosis 10 | 2,010
Alzheimer's disease 9 | 658
Multiple myeloma 9 | 1,332
Vascular disease 9 | 319
Waldenstrons macroglobulinemia 9 | 765
cystic fibrosis 9 | 1,696
Diabetes Mellitus, Experimental 8 | 108
astrocytoma 8 | 1,146
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Parkinson's disease 7 | 392
Prostatic Neoplasms 7 | 495
acute quadriplegic myopathy 7 | 1,158
pituitary cancer 7 | 1,972
spina bifida 7 | 1,074
Cardiomegaly 6 | 116
Depressive disorder 6 | 409
Disease Models, Animal 6 | 155
Hyperalgesia 6 | 83
Liver Cirrhosis, Experimental 6 | 769
Myocardial Infarction 6 | 151
Toxic encephalopathy 6 | 141
dermatomyositis 6 | 966
pancreatic cancer 6 | 2,398
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Carcinoma, Squamous Cell 5 | 110
Crohn's disease 5 | 321
Cryptorchidism 5 | 296
Down syndrome 5 | 499
Hypertension 5 | 396
Immune system cancer 5 | 140
Intellectual disability 5 | 1,016
Lung disease 5 | 142
Lymphoid leukemia 5 | 160
Mammary Neoplasms 5 | 425
Obesity 5 | 678
Squamous cell carcinoma 5 | 129
Stomach Neoplasms 5 | 300
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
sarcoidosis 5 | 370
ulcerative colitis 5 | 1,819
Adenocarcinoma of lung 4 | 142
Alzheimer Disease 4 | 83
Asthma 4 | 385
Autistic Disorder 4 | 364
Cardiomyopathies 4 | 110
Colorectal Neoplasms 4 | 243
Dementia 4 | 175
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Heart disease 4 | 306
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Leukemia 4 | 104
Lung Neoplasms 4 | 232
Myocardial Ischemia 4 | 169
Osteoporosis 4 | 363
Reperfusion Injury 4 | 86
Seizures 4 | 596
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Blood and immune system 51 | 16,909
Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Nervous System 51 | 16,725
Skin and soft tissues 51 | 17,230
Cardiovascular System 50 | 15,192
Respiratory system 50 | 16,393
Urinary Tract 50 | 16,678

Target Family

Kinase 20 | 634
Non-IDG 19 | 12,091
Enzyme 5 | 4,145
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 51 | 51
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Nuclear pore complex protein Nup214 NUP214 Tbio Non-IDG -2.25062 166.6 35
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435