Development Level

Tbio 11 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

IMPC Phenotype

decreased hematocrit 2 | 46
decreased mean corpuscular vol... 2 | 79
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
edema 1 | 59
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased startle reflex 1 | 112
male infertility 1 | 123
short tibia 1 | 97
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 10 | 11,493
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
Cancer 7 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
medulloblastoma, large-cell 7 | 6,241
lung carcinoma 5 | 2,843
pancreatic cancer 5 | 2,398
psoriasis 5 | 6,694
Hypertension 4 | 396
Impotence 4 | 42
Rheumatoid arthritis 4 | 1,191
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
group 4 medulloblastoma 4 | 1,855
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
Breast cancer 3 | 3,578
Glaucoma 3 | 239
Pick disease 3 | 1,894
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Abnormal vision 2 | 52
Alzheimer's disease 2 | 658
Asthma 2 | 385
Atherosclerosis 2 | 291
Blood Coagulation Disorders 2 | 42
Cerebral Ischemia 2 | 37
Cerebrovascular accident 2 | 63
Cerebrovascular disease 2 | 238
Charcot-Marie-Tooth disease dominant intermediate F 2 | 3
Cholera 2 | 34
Cholestasis 2 | 155
Congenital Heart Defects 2 | 58
Congestive heart failure 2 | 113
Crohn's disease 2 | 321
DOID:2415 2 | 5
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Fibrous dysplasia 2 | 15
Heart Defects, Congenital 2 | 37
Heart disease 2 | 306
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Lung disease 2 | 142
Malignant melanoma of choroid 2 | 3
Malignant melanoma of ciliary body 2 | 3
Malignant melanoma of iris 2 | 4
McCune Albright syndrome 2 | 19
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Ocular cancer 2 | 7
Ocular hypertension 2 | 42
Pertussis 2 | 20
Phakomatosis cesioflammea 2 | 2
Prenatal Injuries 2 | 11
Pseudohypoparathyroidism 2 | 18
Retinal Detachment 2 | 51
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Spasm of cerebral arteries 2 | 3
Uveal melanoma 2 | 20
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
sarcoidosis 2 | 370
tuberculosis 2 | 2,010
Abnormal respiratory patterns 1 | 20
Cerebral cortex myoclonus 1 | 3
HYPOCALCEMIA, AUTOSOMAL DOMINANT 1 1 | 2
HYPOCALCEMIA, AUTOSOMAL DOMINANT 2 1 | 1
HYPOCALCIURIC HYPERCALCEMIA, FAMILIAL, TYPE II (disorder) 1 | 1
Hypermagnesiuria 1 | 3
Hypocalciuric hypercalcemia, familial, type II 1 | 1
Increased calcium level in kidney 1 | 21
Myasthenias 1 | 8
Phakomatosis cesiomarmorata 1 | 1
SERUM PHOSPHATE ELEVATED 1 | 14

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Female tissues 14 | 17,400
Nervous System 14 | 16,725
Respiratory system 13 | 16,393

Target Family

Non-IDG 8 | 12,091
Enzyme 3 | 4,145
GPCR 2 | 408
Kinase 2 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Proteinase-activated receptor 4 F2RL3 Tchem GPCR -1.50044 34.1 276
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
Proteinase-activated receptor 3 F2RL2 Tbio GPCR -0.33786 2.70 169
Prothrombin F2 Tclin Enzyme -4.53745 33691.4 579
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 GNG2 Tbio Non-IDG -0.97424 10.0 75
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501