Development Level

Tbio 9 | 11,445
Tchem 6 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
absent startle reflex 1 | 24
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased or absent threshold ... 1 | 101
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
Cancer 8 | 2,499
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
Neoplasm Invasiveness 6 | 161
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pancreatic cancer 6 | 2,398
Neoplasm Metastasis 5 | 168
acute quadriplegic myopathy 5 | 1,158
diabetes mellitus 5 | 1,728
ependymoma 5 | 4,679
esophageal adenocarcinoma 5 | 737
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
Amyotrophic lateral sclerosis 3 | 451
Breast cancer 3 | 3,578
Carcinoma, Squamous Cell 3 | 110
Disease Models, Animal 3 | 155
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Neurodegenerative disease 3 | 414
Schizophrenia 3 | 1,160
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
Arthritis 2 | 290
Arthritis, Juvenile 2 | 126
Asthma 2 | 385
Brain Ischemia 2 | 110
CEROID LIPOFUSCINOSIS, NEURONAL, 6 2 | 6
Carcinoma, Hepatocellular 2 | 228
Cardiomegaly 2 | 116
Cardiomyopathies 2 | 110
Cholestasis, Extrahepatic 2 | 25
Cocaine-Related Disorders 2 | 92
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Female infertility 2 | 30
Gastrointestinal system disease 2 | 54
Gliosis 2 | 56
Head and Neck Neoplasms 2 | 26
Heart disease 2 | 306
Hyperalgesia 2 | 83
Hypertrophy 2 | 17
Infertility, Female 2 | 28
Juvenile arthritis 2 | 126
Kidney Neoplasm 2 | 29
Kidney Neoplasms 2 | 37
Liver Neoplasms, Experimental 2 | 59
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Melanoma 2 | 711
Mental Depression 2 | 333
Nerve Degeneration 2 | 121
Ovarian Neoplasms 2 | 102
Pneumonia, Pneumococcal 2 | 6
Prostatic Neoplasms 2 | 495
Radiation Injuries, Experimental 2 | 11
Sepsis 2 | 24
Skin cancer 2 | 469
Squamous cell carcinoma 2 | 129
Streptococcal pneumonia 2 | 6
Substance Withdrawal Syndrome 2 | 55
Trigeminal Neuralgia 2 | 24
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
ovarian neoplasm 2 | 99
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Abdominal Pain 1 | 98
Coronary Disease 1 | 25

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Enzyme 8 | 4,145
Kinase 5 | 634
Non-IDG 2 | 12,091

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Rab11 family-interacting protein 3 RAB11FIP3 Tbio Non-IDG -0.89095 6.62 68
Phospholipase D2 PLD2 Tchem Enzyme -2.47197 312.2 172
Phospholipase D1 PLD1 Tchem Enzyme -1.51188 30.9 203
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha PIP5K1A Tbio Kinase -0.63348 5.88 121
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
ADP-ribosylation factor 6 ARF6 Tbio Enzyme -2.48917 350.7 310