Development Level

Tchem 6 | 1,598

IMPC Phenotype

increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499

Disease

Breast cancer 6 | 3,578
Cancer 6 | 2,499
lung cancer 5 | 4,740
ovarian cancer 5 | 8,520
Breast Neoplasms 4 | 445
Carcinoma 4 | 11,493
Mammary Neoplasms 4 | 425
atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Ataxia telangiectasia 3 | 34
Bladder Neoplasm 3 | 112
Carcinoma, Hepatocellular 3 | 228
Liver carcinoma 3 | 240
Nijmegen breakage syndrome 3 | 24
Pancreatic Neoplasm 3 | 85
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Stomach Neoplasms 3 | 300
Urinary Bladder Neoplasms 3 | 114
adrenocortical carcinoma 3 | 1,428
glioblastoma 3 | 5,792
primitive neuroectodermal tumor 3 | 3,035
Abnormality of metabolism/homeostasis 2 | 134
Adenoid Cystic Carcinoma 2 | 99
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Squamous Cell 2 | 110
Chronic Lymphocytic Leukemia 2 | 262
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
DOID:2627 2 | 94
DOID:9917 2 | 31
Disease Progression 2 | 136
Encephalopathy, progressive 2 | 6
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Epilepsy 2 | 792
Gastrointestinal stromal tumor 2 | 62
Glioma 2 | 74
Hereditary Breast and Ovarian Cancer Syndrome 2 | 14
Immune system cancer 2 | 140
Increased risk of pancreatic cancer 2 | 9
Kidney cancer 2 | 2,613
Large intestine cancer 2 | 126
Leukemia, Lymphocytic, Chronic, B-Cell 2 | 34
Li-Fraumeni syndrome 2 | 13
Li-Fraumeni syndrome 2 2 | 2
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Lymphoma 2 | 81
Lymphoma, Non-Hodgkin 2 | 24
Lymphoma, T-Cell, Cutaneous 2 | 22
Malignant neoplasm of pancreas 2 | 9
Malignant neoplasm of prostate 2 | 11
Malignant neoplasm of skin 2 | 15
Melanoma 2 | 711
Myocardial Infarction 2 | 151
Nervous System Neoplasms 2 | 8
Neurodegenerative disease 2 | 414
Osteogenic Sarcoma 2 | 6
Pancreatic Neoplasms 2 | 85
Polycystic ovary syndrome 2 | 360
Progressive brain disease 2 | 6
Renal Cell Carcinoma 2 | 214
Retinal Neoplasms 2 | 3
Retinoblastoma 2 | 19
Sarcoma 2 | 62
Seizures 2 | 596
Skin Neoplasms 2 | 69
Skin cancer 2 | 469
Splenomegaly 2 | 190
Squamous cell carcinoma 2 | 129
Stomach cancer 2 | 30
Tumors of Adrenal Cortex 2 | 3
Urinary bladder cancer 2 | 36
Xeroderma pigmentosum 2 | 43
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
Chronic Obstructive Airway Disease 1 | 37
Ischemia 1 | 28
Liver Diseases, Parasitic 1 | 9
Nausea 1 | 20
Papilledema 1 | 11
Penile Neoplasms 1 | 4
Vulvar Lichen Sclerosus 1 | 2

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Kinase 3 | 634
Enzyme 1 | 4,145
Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase PLK3 PLK3 Tchem Kinase -1.92921 94.0 185
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Serine-protein kinase ATM ATM Tchem Kinase -3.57054 3681.6 1024
G1/S-specific cyclin-E1 CCNE1 Tchem Non-IDG -2.47823 262.4 894
M-phase inducer phosphatase 3 CDC25C Tchem Enzyme -2.53550 308.3 810