Development Level

Tchem 15 | 1,598
Tclin 9 | 613
Tbio 6 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Cancer 24 | 2,499
Carcinoma 24 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 18 | 7,950
psoriasis 17 | 6,694
Schizophrenia 14 | 1,160
glioblastoma 14 | 5,792
lung cancer 14 | 4,740
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
Breast cancer 12 | 3,578
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
astrocytoma 9 | 1,146
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Carcinoma, Squamous Cell 8 | 110
Kidney cancer 8 | 2,613
Prostatic Neoplasms 8 | 495
Squamous cell carcinoma 8 | 129
Stomach Neoplasms 8 | 300
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
malignant mesothelioma 8 | 3,232
Bipolar Disorder 7 | 666
Obesity 7 | 678
adult high grade glioma 7 | 3,801
group 4 medulloblastoma 7 | 1,855
Arthritis 6 | 290
Kaposi's Sarcoma Skin Lesions 6 | 8
Primary cutaneous T-cell lymphoma 6 | 29
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
tuberculosis 6 | 2,010
Depressive disorder 5 | 409
Disease Models, Animal 5 | 155
Intellectual disability 5 | 1,016
Lung Neoplasms 5 | 232
Short stature 5 | 531
Vascular disease 5 | 319
Waldenstrons macroglobulinemia 5 | 765
aldosterone-producing adenoma 5 | 665
astrocytic glioma 5 | 2,597
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
ulcerative colitis 5 | 1,819
Alzheimer's disease 4 | 658
Cardiomyopathies 4 | 110
Chronic Lymphocytic Leukemia 4 | 262
Crohn's disease 4 | 321
Dull intelligence 4 | 645
Endometriosis 4 | 540
Heart disease 4 | 306
Hyperalgesia 4 | 83
Hyperkeratosis 4 | 50
Hypoplastic mandible condyle 4 | 275
Kidney disease 4 | 430
Low intelligence 4 | 645
Lung disease 4 | 142
Mandibular hypoplasia 4 | 275
Mental Depression 4 | 333
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Micrognathism 4 | 275
Mood Disorders 4 | 184
Multiple myeloma 4 | 1,332
Osteoporosis 4 | 363
Pick disease 4 | 1,894
Poor school performance 4 | 645
Trigeminal Neuralgia 4 | 24
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Acquired scoliosis 3 | 281
Bilateral fifth finger clinodactyly 3 | 110
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Hyperreflexia 3 | 209
Inflammatory bowel disease 3 | 151
Multiple Sclerosis 3 | 540
Nasal bridge wide 3 | 236
Neurodegenerative disease 3 | 414
Parkinson's disease 3 | 392
Pectus excavatum 3 | 100
Pediatric failure to thrive 3 | 365
Peripheral T-cell lymphoma 3 | 25
Seizures 3 | 596
Toxic encephalopathy 3 | 141
pediatric high grade glioma 3 | 1,064

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Skin and soft tissues 30 | 17,230
Cardiovascular System 29 | 15,192
Respiratory system 29 | 16,393
Urinary Tract 29 | 16,678

Target Family

Kinase 10 | 634
Epigenetic 7 | 242
Nuclear Receptor 7 | 48
Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear receptor-interacting protein 1 NRIP1 Tbio Non-IDG -2.21323 183.8 155
Retinoic acid receptor RXR-beta RXRB Tclin Nuclear Receptor -1.72557 49.3 274
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Vitamin D3 receptor VDR Tclin Nuclear Receptor -3.62166 3805.7 575
Retinol-binding protein 1 RBP1 Tbio Non-IDG -2.65868 476.2 195
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201
Nuclear receptor corepressor 2 NCOR2 Tchem Transcription Factor -2.83392 645.1 189
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417