Development Level

Tbio 11 | 11,445
Tchem 11 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal femur morphology 1 | 14
decreased circulating glucose ... 1 | 126
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
tremors 1 | 39

Disease

Cancer 22 | 2,499
Carcinoma 20 | 11,493
ovarian cancer 17 | 8,520
glioblastoma 16 | 5,792
atypical teratoid / rhabdoid tumor 15 | 5,112
osteosarcoma 15 | 7,950
Breast cancer 12 | 3,578
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
psoriasis 12 | 6,694
Kidney cancer 10 | 2,613
invasive ductal carcinoma 10 | 2,951
Astrocytoma, Pilocytic 9 | 3,081
Schizophrenia 9 | 1,160
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
juvenile dermatomyositis 9 | 1,187
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
Vascular disease 8 | 319
adult high grade glioma 8 | 3,801
ductal carcinoma in situ 8 | 1,745
malignant mesothelioma 8 | 3,232
Gliosis 7 | 56
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
Arthritis 6 | 290
Carcinoma, Squamous Cell 6 | 110
Cardiomyopathies 6 | 110
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Squamous cell carcinoma 6 | 129
colon cancer 6 | 1,478
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Acquired scoliosis 5 | 281
Alzheimer's disease 5 | 658
Curvature of spine 5 | 282
Lung Neoplasms 5 | 232
Neoplasm Invasiveness 5 | 161
Pectus excavatum 5 | 100
Pick disease 5 | 1,894
Renal Cell Carcinoma 5 | 214
Stomach Neoplasms 5 | 300
gastric carcinoma 5 | 807
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Congenital deafness 4 | 185
Deafness 4 | 198
Depressive disorder 4 | 409
Epilepsy 4 | 792
Frontal bossing 4 | 157
Hearing Loss, Partial 4 | 185
Hyperglycemia 4 | 137
Hyperkyphosis 4 | 111
Intellectual disability 4 | 1,016
Joint hyperflexibility 4 | 78
Joint laxity 4 | 54
Kyphosis deformity of spine 4 | 114
Lymphedema 4 | 42
Mammary Neoplasms 4 | 425
Mental Depression 4 | 333
Multiple Sclerosis 4 | 540
Muscle hypotonia 4 | 571
Myopia 4 | 176
Neoplasm Metastasis 4 | 168
Ovarian Neoplasms 4 | 102
Parkinson's disease 4 | 392
Short stature 4 | 531
Testicular Hydrocele 4 | 8
Triangular face 4 | 58
hearing impairment 4 | 199
nasopharyngeal carcinoma 4 | 1,058
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
Abortion, Spontaneous 3 | 109
Byzanthine arch palate 3 | 194
Concave bridge of nose 3 | 195
Congenital Epicanthus 3 | 177
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Kidney disease 3 | 430
Lung disease 3 | 142
Spontaneous abortion 3 | 113
pterygium 3 | 76
urothelial carcinoma 3 | 318

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 15 | 12,091
Kinase 10 | 634
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Vascular endothelial growth factor receptor 3 FLT4 Tclin Kinase -2.72966 518.8 744
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667
Integrin alpha-4 ITGA4 Tclin Non-IDG -2.53262 310.4 1312
Ribosomal protein S6 kinase alpha-1 RPS6KA1 Tchem Kinase -2.57872 338.0 1158
Integrin alpha-5 ITGA5 Tbio Non-IDG -2.29130 169.1 826
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.98303 874.8 508
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440