Development Level

Tbio 23 | 11,445
Tchem 15 | 1,598
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal skin morphology 3 | 50
abnormal retina morphology 2 | 71
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal tooth morphology 1 | 24
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 34 | 11,493
ovarian cancer 31 | 8,520
Cancer 28 | 2,499
lung cancer 25 | 4,740
Breast cancer 24 | 3,578
glioblastoma 24 | 5,792
medulloblastoma, large-cell 23 | 6,241
osteosarcoma 23 | 7,950
pancreatic cancer 23 | 2,398
psoriasis 22 | 6,694
atypical teratoid / rhabdoid tumor 21 | 5,112
malignant mesothelioma 21 | 3,232
invasive ductal carcinoma 20 | 2,951
Kidney cancer 19 | 2,613
lung adenocarcinoma 19 | 2,716
lung carcinoma 18 | 2,843
ependymoma 17 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Autosomal recessive predisposition 16 | 1,442
breast carcinoma 16 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Schizophrenia 15 | 1,160
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
non-small cell lung cancer 14 | 2,890
primary pancreatic ductal adenocarcinoma 14 | 1,109
Astrocytoma, Pilocytic 13 | 3,081
dermatomyositis 13 | 966
ductal carcinoma in situ 13 | 1,745
group 4 medulloblastoma 13 | 1,855
juvenile dermatomyositis 12 | 1,187
Breast Neoplasms 11 | 445
Neoplasm Metastasis 11 | 168
Prostatic Neoplasms 11 | 495
cystic fibrosis 11 | 1,696
oligodendroglioma 11 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Mammary Neoplasms 10 | 425
adult high grade glioma 10 | 3,801
group 3 medulloblastoma 10 | 4,104
ulcerative colitis 10 | 1,819
Disease Progression 9 | 136
astrocytic glioma 9 | 2,597
diabetes mellitus 9 | 1,728
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
Carcinoma, Squamous Cell 8 | 110
Duchenne muscular dystrophy 8 | 601
Failure to gain weight 8 | 365
Pediatric failure to thrive 8 | 365
Squamous cell carcinoma 8 | 129
Stomach Neoplasms 8 | 300
acute quadriplegic myopathy 8 | 1,158
esophageal adenocarcinoma 8 | 737
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
Carcinoma, Hepatocellular 7 | 228
Heart disease 7 | 306
Liver carcinoma 7 | 240
Lung Neoplasms 7 | 232
Muscle hypotonia 7 | 571
Myopia 7 | 176
astrocytoma 7 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
nasopharyngeal carcinoma 7 | 1,058
ANONYCHIA 6 | 20
Adenoma 6 | 167
Anemia 6 | 365
Animal Mammary Neoplasms 6 | 136
Aplasia Cutis Congenita 6 | 14
Atrophic scar 6 | 18
Barrett's esophagus 6 | 182
Colorectal Neoplasms 6 | 243
Congenital scar 6 | 13
Death in early childhood 6 | 82
Death in infancy 6 | 82
Dental Enamel Hypoplasia 6 | 43
Down syndrome 6 | 499
Dystrophia unguium 6 | 53
Endometrial cancer 6 | 311
Endometriosis 6 | 540
Epidermolysis bullosa 6 | 21
Epilepsy 6 | 792
Hypodontia 6 | 81
Liver cancer 6 | 604
Mammary Neoplasms, Animal 6 | 136
Mammary Neoplasms, Experimental 6 | 154
Melanoma 6 | 711
Milium Cyst 6 | 16
Multiple myeloma 6 | 1,332
Nail dysplasia 6 | 52
Neoplasm Invasiveness 6 | 161
Ovarian Neoplasms 6 | 102
Pick disease 6 | 1,894
Prenatal onset 6 | 139
Seizures 6 | 596
active ulcerative colitis 6 | 764
colon cancer 6 | 1,478
non-small cell lung carcinoma 6 | 317

Tissue

Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 10 | 634
Enzyme 5 | 4,145
Nuclear Receptor 3 | 48

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Retinoic acid receptor RXR-beta RXRB Tclin Nuclear Receptor -1.72557 49.3 274
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
Hepatocyte growth factor-like protein MST1 Tbio Enzyme -2.04160 93.5 0
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982