Development Level

Tchem 17 | 1,598
Tbio 16 | 11,445
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased circulating triglyce... 3 | 79
abnormal bone structure 2 | 187
abnormal bone mineralization 1 | 38
abnormal clavicle morphology 1 | 6
abnormal cornea morphology 1 | 31
abnormal joint morphology 1 | 23
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased vertical activity 1 | 208
increased B cell number 1 | 9
increased T cell number 1 | 6
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
shortened RR interval 1 | 17

Disease

Carcinoma 23 | 11,493
medulloblastoma, large-cell 22 | 6,241
ovarian cancer 21 | 8,520
glioblastoma 20 | 5,792
psoriasis 19 | 6,694
Cancer 18 | 2,499
osteosarcoma 18 | 7,950
atypical teratoid / rhabdoid tumor 17 | 5,112
lung cancer 17 | 4,740
group 3 medulloblastoma 15 | 4,104
diabetes mellitus 12 | 1,728
ependymoma 12 | 4,679
malignant mesothelioma 12 | 3,232
Breast cancer 11 | 3,578
ulcerative colitis 11 | 1,819
adult high grade glioma 10 | 3,801
primitive neuroectodermal tumor 10 | 3,035
Myocardial Infarction 9 | 151
Vascular disease 9 | 319
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
pancreatic cancer 9 | 2,398
Alzheimer's disease 8 | 658
Astrocytoma, Pilocytic 8 | 3,081
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
subependymal giant cell astrocytoma 8 | 2,287
Amyotrophic lateral sclerosis 7 | 451
Obesity 7 | 678
Renal Cell Carcinoma 7 | 214
colon cancer 7 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
Carcinoma, Hepatocellular 6 | 228
Cell Transformation, Neoplastic 6 | 97
Heart disease 6 | 306
Liver carcinoma 6 | 240
Neoplastic Cell Transformation 6 | 89
Parkinson's disease 6 | 392
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
pediatric high grade glioma 6 | 1,064
Adenoma 5 | 167
Atherosclerosis 5 | 291
Autistic Disorder 5 | 364
Brain Ischemia 5 | 110
Carcinoma, Renal Cell 5 | 124
Colonic Neoplasms 5 | 142
Depressive disorder 5 | 409
Diabetes Mellitus, Experimental 5 | 108
Heart failure 5 | 162
Hypertension 5 | 396
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Liver disease 5 | 237
Liver neoplasms 5 | 130
Lung Neoplasms 5 | 232
Lung disease 5 | 142
Reperfusion Injury 5 | 86
Status Epilepticus 5 | 98
Stomach Neoplasms 5 | 300
Toxic encephalopathy 5 | 141
active Crohn's disease 5 | 922
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Adenocarcinoma 4 | 122
Arthritis 4 | 290
Asthma 4 | 385
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Brain disease 4 | 96
Coronary artery disease 4 | 268
Endometriosis 4 | 540
Epilepsy 4 | 792
Hyperglycemia 4 | 137
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Marijuana Abuse 4 | 31
Melanoma 4 | 711
Mental Depression 4 | 333
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
invasive ductal carcinoma 4 | 2,951
nasopharyngeal carcinoma 4 | 1,058
primary pancreatic ductal adenocarcinoma 4 | 1,109
dermatomyositis 3 | 966
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Blood and immune system 35 | 16,909
Cardiovascular System 35 | 15,192
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678

Target Family

Transcription Factor 14 | 1,400
Kinase 8 | 634
Non-IDG 7 | 12,091
Enzyme 4 | 4,145
Nuclear Receptor 1 | 48
Transporter 1 | 473

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Keratin, type I cytoskeletal 19 KRT19 Tbio Non-IDG -3.23530 1627.1 1789