Development Level

Tbio 15 | 11,445
Tchem 10 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased circulating alkaline... 2 | 122
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal glucose homeostasis 1 | 4
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
edema 1 | 59
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

ovarian cancer 18 | 8,520
psoriasis 16 | 6,694
Carcinoma 15 | 11,493
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 13 | 5,792
osteosarcoma 13 | 7,950
ependymoma 12 | 4,679
medulloblastoma, large-cell 12 | 6,241
adult high grade glioma 11 | 3,801
diabetes mellitus 11 | 1,728
Bipolar Disorder 10 | 666
Cancer 10 | 2,499
Breast cancer 8 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung cancer 8 | 4,740
Obesity 7 | 678
Schizophrenia 7 | 1,160
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
oligodendroglioma 7 | 2,850
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
Hyperglycemia 6 | 137
Hyperinsulinism 6 | 133
Multiple myeloma 6 | 1,332
acute quadriplegic myopathy 6 | 1,158
dermatomyositis 6 | 966
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Insulin Resistance 5 | 72
Pick disease 5 | 1,894
Polycystic ovary syndrome 5 | 360
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary pancreatic ductal adenocarcinoma 5 | 1,109
primitive neuroectodermal tumor 5 | 3,035
spina bifida 5 | 1,074
Acanthosis Nigricans 4 | 27
Alzheimer Disease 4 | 83
Cardiomegaly 4 | 116
Cognitive delay 4 | 608
Diabetes Mellitus, Type 2 4 | 142
Epilepsy 4 | 792
Global developmental delay 4 | 608
Kidney cancer 4 | 2,613
Lipodystrophy 4 | 40
Liver Cirrhosis, Experimental 4 | 769
Mental and motor retardation 4 | 608
Parkinson's disease 4 | 392
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
ductal carcinoma in situ 4 | 1,745
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
Autosomal recessive predisposition 3 | 1,442
Cardiomyopathies 3 | 110
Dementia 3 | 175
Depressive disorder 3 | 409
Diabetes Mellitus, Experimental 3 | 108
Diabetes Mellitus, Noninsulin-Dependent 3 | 31
Gynecomastia 3 | 64
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypoglycemia 3 | 152
Hypothyroidism 3 | 122
Insulin resistant diabetes 3 | 13
Lipid metabolism disorder 3 | 114
Mental Depression 3 | 333
Myopathy 3 | 185
Orbital separation excessive 3 | 244
Rheumatoid arthritis 3 | 1,191
Waldenstrons macroglobulinemia 3 | 765
breast carcinoma 3 | 1,638
juvenile dermatomyositis 3 | 1,187
Acromegaly 2 | 51
Adenoma 2 | 167
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Anteverted nostril 2 | 191
Cardiovascular Diseases 2 | 59
Concave bridge of nose 2 | 195
Depressed nasal root/bridge 2 | 195
Glycogen storage disease 2 | 39
Heart disease 2 | 306
Impaired cognition 2 | 96
Kidney disease 2 | 430
Lung disease 2 | 142
MAJOR AFFECTIVE DISORDER 2 2 | 22
Major Depressive Disorder 2 | 301
Mood Disorders 2 | 184
Neuropathy 2 | 261
Short nose 2 | 132
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
hereditary spastic paraplegia 2 | 318

Tissue

Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678

Target Family

Non-IDG 15 | 12,091
Kinase 6 | 634
Enzyme 5 | 4,145
Transporter 1 | 473

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Protein phosphatase 1 regulatory subunit 3A PPP1R3A Tbio Enzyme -1.36272 22.6 88
Rho-related GTP-binding protein RhoQ RHOQ Tbio Enzyme -1.48059 28.3 111
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
TBC1 domain family member 4 TBC1D4 Tbio Non-IDG -2.06751 113.5 300
Syntaxin-4 STX4 Tbio Non-IDG -1.95295 84.2 207
Protein kinase C iota type PRKCI Tchem Kinase -1.71694 51.2 148
14-3-3 protein zeta/delta YWHAZ Tbio Non-IDG -2.59435 390.4 689
Leucyl-cystinyl aminopeptidase LNPEP Tchem Enzyme -2.57244 394.0 103