Development Level

Tbio 10 | 11,445
Tchem 9 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased circulating iron lev... 1 | 32
edema 1 | 59
enlarged lymph nodes 1 | 37
increased body length 1 | 32
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased heart rate 1 | 23
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
shortened RR interval 1 | 17

Disease

ependymoma 14 | 4,679
glioblastoma 13 | 5,792
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
Cancer 12 | 2,499
Carcinoma 12 | 11,493
medulloblastoma, large-cell 12 | 6,241
psoriasis 12 | 6,694
atypical teratoid / rhabdoid tumor 11 | 5,112
Breast cancer 8 | 3,578
adult high grade glioma 8 | 3,801
lung adenocarcinoma 8 | 2,716
Astrocytoma, Pilocytic 7 | 3,081
astrocytic glioma 7 | 2,597
lung cancer 7 | 4,740
oligodendroglioma 7 | 2,850
Bipolar Disorder 6 | 666
malignant mesothelioma 6 | 3,232
subependymal giant cell astrocytoma 6 | 2,287
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
ulcerative colitis 5 | 1,819
Parkinson's disease 4 | 392
colon cancer 4 | 1,478
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
Alzheimer's disease 3 | 658
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Squamous Cell 3 | 110
Cardiomyopathies 3 | 110
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Liver carcinoma 3 | 240
Mental and motor retardation 3 | 608
Mouth Neoplasms 3 | 55
Pick disease 3 | 1,894
Renal Cell Carcinoma 3 | 214
Squamous cell carcinoma 3 | 129
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
Adenocarcinoma of lung 2 | 142
Alcoholic Intoxication, Chronic 2 | 289
Arthritis 2 | 290
Attention deficit hyperactivity disorder 2 | 278
Blepharoptosis 2 | 231
Breast Neoplasms 2 | 445
COPD 2 | 118
Congenital Epicanthus 2 | 177
Crohn's disease 2 | 321
Dementia 2 | 175
Depressive disorder 2 | 409
Downward slant of palpebral fissure 2 | 158
Electroencephalogram abnormal 2 | 101
HIV Infections 2 | 102
Heart disease 2 | 306
High forehead 2 | 102
Hypertrophic Cardiomyopathy 2 | 117
Kidney Neoplasm 2 | 29
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Liver neoplasms 2 | 130
Lung Neoplasms 2 | 232
Major Depressive Disorder 2 | 301
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Nerve Degeneration 2 | 121
Pilocytic astrocytoma 2 | 56
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Tall forehead 2 | 102
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
active Crohn's disease 2 | 922
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010

Tissue

Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192
Respiratory system 20 | 16,393

Target Family

Non-IDG 10 | 12,091
Kinase 5 | 634
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992
Transcription factor E2-alpha TCF3 Tbio Transcription Factor -2.80290 601.6 434
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
14-3-3 protein zeta/delta YWHAZ Tbio Non-IDG -2.59435 390.4 689
MAP kinase-activated protein kinase 2 MAPKAPK2 Tchem Kinase -2.16502 140.7 702
ETS translocation variant 1 ETV1 Tbio Transcription Factor -2.12855 127.1 196
Tuberin TSC2 Tbio Non-IDG -2.99381 1000.6 1632
14-3-3 protein epsilon YWHAE Tbio Non-IDG -2.23108 170.5 348