Development Level

Tbio 16 | 11,445
Tchem 9 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal heart morphology 2 | 162
enlarged heart 2 | 210
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
male infertility 1 | 123
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 21 | 11,493
Cancer 19 | 2,499
osteosarcoma 16 | 7,950
psoriasis 15 | 6,694
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 13 | 6,241
lung cancer 12 | 4,740
diabetes mellitus 10 | 1,728
Breast cancer 9 | 3,578
group 3 medulloblastoma 9 | 4,104
Obesity 8 | 678
atypical teratoid / rhabdoid tumor 8 | 5,112
malignant mesothelioma 8 | 3,232
Schizophrenia 7 | 1,160
ductal carcinoma in situ 7 | 1,745
glioblastoma 7 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
Vascular disease 6 | 319
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
hepatocellular carcinoma 6 | 547
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Adenoid Cystic Carcinoma 5 | 99
Amyotrophic lateral sclerosis 5 | 451
Bladder Neoplasm 5 | 112
Breast Neoplasms 5 | 445
Carcinoma, Adenoid Cystic 5 | 99
Diabetes Mellitus, Experimental 5 | 108
Epilepsy 5 | 792
Lymphoid leukemia 5 | 160
Mammary Neoplasms 5 | 425
Prostatic Neoplasms 5 | 495
Seizures 5 | 596
Urinary Bladder Neoplasms 5 | 114
ependymoma 5 | 4,679
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Adenocarcinoma of lung 4 | 142
Adenocarcinoma of lung (disorder) 4 | 60
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Carcinoma, Squamous Cell 4 | 110
Carcinoma, Transitional Cell 4 | 32
Cryptorchidism 4 | 296
Endometriosis 4 | 540
Esophageal Squamous Cell Carcinoma 4 | 77
Fatty liver disease 4 | 103
Huntington's disease 4 | 76
Immune system cancer 4 | 140
Intellectual disability 4 | 1,016
Mood Disorders 4 | 184
Muscle hypotonia 4 | 571
Parkinson's disease 4 | 392
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
Squamous cell carcinoma 4 | 129
Squamous cell carcinoma of esophagus 4 | 77
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
nasopharyngeal carcinoma 4 | 1,058
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Acute kidney injury 3 | 70
Bilateral fifth finger clinodactyly 3 | 110
Colonic Neoplasms 3 | 142
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Endometrial cancer 3 | 311
Frontal bossing 3 | 157
Glaucoma 3 | 239
HIV Infections 3 | 102
Highly variable severity 3 | 157
Kidney Diseases 3 | 114
Liver Cirrhosis, Experimental 3 | 769
Mesothelioma, Malignant 3 | 105
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Nerve Degeneration 3 | 121
Neurodegenerative disease 3 | 414
Polyhydramnios 3 | 108
Stomach Neoplasms 3 | 300
Variable expressivity 3 | 157
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
gastric cancer 3 | 459
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Male tissues 27 | 17,142
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678

Target Family

Non-IDG 9 | 12,091
Epigenetic 8 | 242
Transcription Factor 7 | 1,400
Enzyme 3 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 Tbio Enzyme -1.48800 26.8 73
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Forkhead box protein O4 FOXO4 Tbio Transcription Factor -2.43923 278.0 720
Four and a half LIM domains protein 2 FHL2 Tbio Non-IDG -2.60042 385.8 253
Homeobox protein Hox-A10 HOXA10 Tbio Transcription Factor -2.31212 210.6 170
Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 Tbio Enzyme -2.25828 174.5 264
NAD-dependent protein deacetylase sirtuin-7 SIRT7 Tbio Epigenetic -2.22094 153.0 348
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.16910 1355.7 632
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298