Development Level

Tbio 32 | 11,651
Tchem 21 | 1,388
Tclin 4 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal retina morphology 2 | 71
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal startle reflex 1 | 15
abnormal vitreous body morphol... 1 | 10
absent testes 1 | 6
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
increased basophil cell number 1 | 7
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased eosinophil cell numb... 1 | 11
increased granulocyte number 1 | 1
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
premature death 1 | 5
small superior vagus ganglion 1 | 74

Disease

Cancer 43 | 2,499
Carcinoma 38 | 11,493
psoriasis 35 | 6,694
ovarian cancer 34 | 8,520
lung cancer 32 | 4,740
osteosarcoma 29 | 7,950
glioblastoma 24 | 5,792
ependymoma 21 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Breast cancer 20 | 3,578
medulloblastoma, large-cell 20 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
malignant mesothelioma 18 | 3,232
Astrocytoma, Pilocytic 17 | 3,081
lung carcinoma 17 | 2,843
pancreatic cancer 17 | 2,398
adult high grade glioma 15 | 3,801
Mammary Neoplasms 14 | 425
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
tuberculosis 14 | 2,010
Breast Neoplasms 13 | 445
group 3 medulloblastoma 13 | 4,104
oligodendroglioma 13 | 2,850
subependymal giant cell astrocytoma 13 | 2,287
non-small cell lung cancer 12 | 2,890
Alzheimer's disease 11 | 658
Hypersensitivity reaction type II disease 11 | 253
Liver Cirrhosis, Experimental 11 | 769
Schizophrenia 11 | 1,160
colon cancer 11 | 1,478
interstitial cystitis 11 | 2,312
invasive ductal carcinoma 11 | 2,951
Prostatic Neoplasms 10 | 495
Splenomegaly 10 | 190
cutaneous lupus erythematosus 10 | 1,057
diabetes mellitus 10 | 1,728
juvenile dermatomyositis 10 | 1,187
primitive neuroectodermal tumor 10 | 3,035
Brain Ischemia 9 | 110
Kidney cancer 9 | 2,613
Liver disease 9 | 237
Parkinson's disease 9 | 392
Rheumatoid arthritis 9 | 1,191
Toxic encephalopathy 9 | 141
acute quadriplegic myopathy 9 | 1,158
astrocytoma 9 | 1,146
cystic fibrosis 9 | 1,696
lung adenocarcinoma 9 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary pancreatic ductal adenocarcinoma 9 | 1,109
Autosomal recessive predisposition 8 | 1,442
Diabetes Mellitus, Experimental 8 | 108
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Obesity 8 | 678
Vascular disease 8 | 319
active ulcerative colitis 8 | 764
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Anemia 7 | 365
Bipolar Disorder 7 | 666
Carcinoma, Hepatocellular 7 | 228
Depressive disorder 7 | 409
Diabetes Mellitus, Type 2 7 | 142
Disease Models, Animal 7 | 155
Epilepsy 7 | 792
Intellectual disability 7 | 1,016
Kidney disease 7 | 430
Liver carcinoma 7 | 240
Lung Neoplasms 7 | 232
Myocardial Reperfusion Injury 7 | 37
Polycystic ovary syndrome 7 | 360
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
gastric carcinoma 7 | 807
primary Sjogren syndrome 7 | 735
Arthritis 6 | 290
Asthma 6 | 385
Atherosclerosis 6 | 291
Atopic dermatitis 6 | 952
Brain disease 6 | 96
Cardiomyopathies 6 | 110
Cerebral Hemorrhage 6 | 42
Cerebrovascular disease 6 | 238
Colorectal Neoplasms 6 | 243
Hepatomegaly 6 | 285
Multiple Sclerosis 6 | 540
Muscle hypotonia 6 | 571
Myocardial Infarction 6 | 151
Renal Cell Carcinoma 6 | 214
Seizures 6 | 596
Stomach Neoplasms 6 | 300
Thrombocytopenia 6 | 197
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
hepatocellular carcinoma 6 | 547
mucosa-associated lymphoid tissue lymphoma 6 | 484
spina bifida 6 | 1,074
Pick disease 5 | 1,894

Tissue

Blood and immune system 57 | 16,909
Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Female tissues 57 | 17,400
Liver and Pancreas 57 | 16,750
Male tissues 57 | 17,142
Nervous System 57 | 16,725
Respiratory system 57 | 16,393
Skin and soft tissues 57 | 17,230
Urinary Tract 57 | 16,678
Cardiovascular System 56 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 13 | 4,145
Kinase 6 | 634
Transcription Factor 3 | 1,400

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.28849 219.7 322
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
DNA fragmentation factor subunit beta DFFB Tbio Non-IDG -1.82600 60.8 383
LIM domain kinase 1 LIMK1 Tchem Kinase -2.28919 187.7 664
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
Baculoviral IAP repeat-containing protein 3 BIRC3 Tchem Non-IDG -2.62553 373.2 500
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045