Development Level

Tbio 19 | 11,445
Tchem 11 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to t... 6 | 278
decreased circulating serum al... 3 | 82
embryonic lethality prior to o... 3 | 239
increased circulating alkaline... 3 | 122
abnormal retina morphology 2 | 71
decreased circulating total pr... 2 | 49
increased circulating iron lev... 2 | 30
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
enlarged kidney 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating insulin ... 1 | 3
increased circulating phosphat... 1 | 26
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 30 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 23 | 7,950
atypical teratoid / rhabdoid tumor 19 | 5,112
ependymoma 19 | 4,679
glioblastoma 19 | 5,792
Cancer 18 | 2,499
psoriasis 16 | 6,694
adult high grade glioma 14 | 3,801
medulloblastoma, large-cell 14 | 6,241
group 3 medulloblastoma 13 | 4,104
Astrocytoma, Pilocytic 12 | 3,081
oligodendroglioma 12 | 2,850
astrocytic glioma 11 | 2,597
primitive neuroectodermal tumor 11 | 3,035
lung cancer 10 | 4,740
Breast cancer 9 | 3,578
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
Intellectual disability 8 | 1,016
Dull intelligence 7 | 645
Kidney cancer 7 | 2,613
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Cryptorchidism 6 | 296
Downward slant of palpebral fissure 6 | 158
Hypotrophic malar bone 6 | 129
Malar flattening 6 | 129
Orbital separation excessive 6 | 244
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
tuberculosis 6 | 2,010
Congenital hypoplasia of penis 5 | 176
Depressive disorder 5 | 409
Frontal bossing 5 | 157
Hydronephrosis 5 | 89
Hypoplastic mandible condyle 5 | 275
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Robinow syndrome 5 | 11
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819
Brachydactyly 4 | 156
Broad flat nasal bridge 4 | 236
Broad thumbs 4 | 28
Cognitive delay 4 | 608
Concave bridge of nose 4 | 195
Delayed bone age 4 | 136
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Exophthalmos 4 | 112
Flat face 4 | 52
Global developmental delay 4 | 608
Heart disease 4 | 306
Hyperalgesia 4 | 83
Hypertension 4 | 396
Hypotrophic midface 4 | 105
Late tooth eruption 4 | 61
Long philtrum 4 | 137
Melanoma 4 | 711
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Midface retrusion 4 | 105
Nasal bridge wide 4 | 236
Osteoporosis 4 | 363
Pectus excavatum 4 | 100
Posteriorly rotated ear 4 | 61
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Reperfusion Injury 4 | 86
Short nose 4 | 132
Small midface 4 | 105
Small nose 4 | 132
Umbilical hernia 4 | 93
Ventricular Septal Defects 4 | 119
Wide anterior fontanel 4 | 44
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
pituitary cancer 4 | 1,972

Tissue

Digestive Tract 33 | 17,369
Female tissues 33 | 17,400
Male tissues 33 | 17,142
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Endocrine System 32 | 18,159
Liver and Pancreas 32 | 16,750
Nervous System 32 | 16,725
Urinary Tract 32 | 16,678

Target Family

Kinase 12 | 634
Non-IDG 9 | 12,091
Enzyme 4 | 4,145
GPCR 4 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 33 | 33
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
Collagen triple helix repeat-containing protein 1 CTHRC1 Tbio Non-IDG -1.72221 62.3 202
Frizzled-6 FZD6 Tbio GPCR -1.63747 44.5 260
Frizzled-5 FZD5 Tbio GPCR -1.54924 30.5 307