Development Level

Tchem 11 | 1,598
Tbio 10 | 11,445
Tclin 9 | 613

IMPC Phenotype

decreased heart weight 2 | 27
abnormal behavior 1 | 298
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Cancer 29 | 2,499
Carcinoma 22 | 11,493
psoriasis 20 | 6,694
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 18 | 6,241
osteosarcoma 18 | 7,950
glioblastoma 15 | 5,792
lung cancer 15 | 4,740
Rheumatoid arthritis 13 | 1,191
malignant mesothelioma 12 | 3,232
Schizophrenia 11 | 1,160
invasive ductal carcinoma 11 | 2,951
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
lung adenocarcinoma 10 | 2,716
interstitial cystitis 9 | 2,312
tuberculosis 9 | 2,010
Hypersensitivity reaction type II disease 8 | 253
Multiple Sclerosis 8 | 540
ductal carcinoma in situ 8 | 1,745
ependymoma 8 | 4,679
group 4 medulloblastoma 8 | 1,855
Anemia 7 | 365
Autosomal recessive predisposition 7 | 1,442
Multiple myeloma 7 | 1,332
cutaneous lupus erythematosus 7 | 1,057
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
Asthma 6 | 385
Failure to gain weight 6 | 365
Hepatomegaly 6 | 285
Immune system cancer 6 | 140
Kidney cancer 6 | 2,613
Lung Neoplasms 6 | 232
Lymphoid leukemia 6 | 160
Pediatric failure to thrive 6 | 365
Prostatic Neoplasms 6 | 495
Severe combined immunodeficiency 6 | 51
Splenomegaly 6 | 190
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
sarcoidosis 6 | 370
Acquired immunodeficiency syndrome 5 | 197
Adenocarcinoma 5 | 122
Angle class 2 malocclusion 5 | 57
Angle class 3 malocclusion 5 | 57
Arthritis, Rheumatoid 5 | 174
Diarrhea 5 | 253
Leukemia, Myeloid, Acute 5 | 105
Malocclusion 5 | 57
Mesothelioma, Malignant 5 | 105
Neoplasm Metastasis 5 | 168
Pneumonia 5 | 174
Type 1 diabetes mellitus 5 | 109
Vascular disease 5 | 319
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
primary Sjogren syndrome 5 | 735
Adenoma 4 | 167
Arthritis 4 | 290
Atopic dermatitis 4 | 952
Autistic Disorder 4 | 364
Breast Neoplasms 4 | 445
Chronic Lymphocytic Leukemia 4 | 262
Cognitive delay 4 | 608
Dermatitis, Allergic Contact 4 | 67
Fever 4 | 138
Global developmental delay 4 | 608
High forehead 4 | 102
Hypoplastic mandible condyle 4 | 275
Inflammatory bowel disease 4 | 151
Leukemia, Myelocytic, Acute 4 | 120
Liver Cirrhosis, Experimental 4 | 769
Lung disease 4 | 142
Lymphadenopathy 4 | 62
Mammary Neoplasms 4 | 425
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Muscle hypotonia 4 | 571
Orbital separation excessive 4 | 244
Polycythemia vera 4 | 27
Tall forehead 4 | 102
Thrombocytopenia 4 | 197
Ventricular Septal Defects 4 | 119
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
nasopharyngeal carcinoma 4 | 1,058
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Cardiovascular System 27 | 15,192
Nervous System 27 | 16,725

Target Family

Non-IDG 17 | 12,091
Kinase 6 | 634
Transcription Factor 6 | 1,400
Enzyme 1 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Perforin-1 PRF1 Tchem Non-IDG -3.20526 1546.3 367
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
Tyrosine-protein kinase JAK3 JAK3 Tclin Kinase -2.64385 453.7 292
Interleukin-2 receptor subunit beta IL2RB Tclin Non-IDG -2.17998 125.4 654
Interleukin-2 receptor subunit alpha IL2RA Tclin Non-IDG -3.02107 927.8 1917
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501