Development Level

Tbio 17 | 11,445
Tchem 10 | 1,598
Tclin 6 | 613

IMPC Phenotype

abnormal eye anterior chamber ... 2 | 9
decreased heart weight 2 | 27
increased monocyte cell number 2 | 63
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal colon morphology 1 | 3
abnormal digit morphology 1 | 10
abnormal duodenum morphology 1 | 4
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal social-conspecific in... 1 | 3
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123

Disease

osteosarcoma 21 | 7,950
psoriasis 21 | 6,694
Cancer 20 | 2,499
Carcinoma 20 | 11,493
lung cancer 18 | 4,740
lung carcinoma 18 | 2,843
glioblastoma 16 | 5,792
interstitial cystitis 16 | 2,312
Rheumatoid arthritis 15 | 1,191
cutaneous lupus erythematosus 15 | 1,057
diabetes mellitus 15 | 1,728
ovarian cancer 15 | 8,520
Asthma 12 | 385
Hypersensitivity reaction type II disease 12 | 253
Arthritis 11 | 290
ulcerative colitis 11 | 1,819
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
Inflammatory bowel disease 10 | 151
Multiple Sclerosis 10 | 540
Schizophrenia 10 | 1,160
ependymoma 10 | 4,679
tuberculosis 10 | 2,010
Autosomal recessive predisposition 9 | 1,442
Kidney disease 9 | 430
Lung disease 9 | 142
adult high grade glioma 9 | 3,801
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
Crohn's disease 8 | 321
Liver disease 8 | 237
atypical teratoid / rhabdoid tumor 8 | 5,112
invasive ductal carcinoma 8 | 2,951
medulloblastoma, large-cell 8 | 6,241
Dermatitis 7 | 157
Heart disease 7 | 306
Immunologic Deficiency Syndromes 7 | 113
primary Sjogren syndrome 7 | 735
sarcoidosis 7 | 370
subependymal giant cell astrocytoma 7 | 2,287
Allergic hypersensitivity disease 6 | 126
Arthritis, Rheumatoid 6 | 174
Atherosclerosis 6 | 291
Celiac disease 6 | 116
Inflammation 6 | 120
Leishmaniasis 6 | 47
Lung Neoplasms 6 | 232
Obesity 6 | 678
Pneumonia 6 | 174
Prostatic Neoplasms 6 | 495
Recurrent respiratory infections 6 | 141
Renal transplant rejection 6 | 13
Vascular disease 6 | 319
pituitary cancer 6 | 1,972
Anemia 5 | 365
Autistic Disorder 5 | 364
Brain Injuries 5 | 65
Cell Transformation, Neoplastic 5 | 97
Cholestasis, Extrahepatic 5 | 25
Depressive disorder 5 | 409
Dermatitis, Allergic Contact 5 | 67
Disease Models, Animal 5 | 155
Eye disease 5 | 62
Hepatitis B 5 | 108
Hepatitis, Autoimmune 5 | 17
Human immunodeficiency virus infectious disease 5 | 138
Hypereosinophilic syndrome 5 | 71
Liver Cirrhosis, Experimental 5 | 769
Major Depressive Disorder 5 | 301
Neoplasm Metastasis 5 | 168
Reperfusion Injury 5 | 86
Severe combined immunodeficiency 5 | 51
Tetanus 5 | 68
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic cancer 5 | 2,398
Allergic rhinitis 4 | 94
Autoimmune Diseases 4 | 67
Bipolar Disorder 4 | 666
Carcinoma, Hepatocellular 4 | 228
Collagen disease 4 | 27
Decreased joint mobility 4 | 53
Failure to gain weight 4 | 365
Hepatomegaly 4 | 285
Hypertension 4 | 396
Infantile onset 4 | 238
Kidney cancer 4 | 2,613
Liver carcinoma 4 | 240
Malaria 4 | 160
Mental Depression 4 | 333
Pediatric failure to thrive 4 | 365
Stomach Neoplasms 4 | 300
Unipolar Depression 4 | 250
active Crohn's disease 4 | 922
breast carcinoma 4 | 1,638
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Skin and soft tissues 31 | 17,230
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Urinary Tract 30 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 21 | 12,091
Transcription Factor 9 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Perforin-1 PRF1 Tchem Non-IDG -3.20526 1546.3 367
T-cell receptor beta-1 chain C region TRBC1 Tbio Non-IDG 0.00000 0
T-cell surface glycoprotein CD3 gamma chain CD3G Tclin Non-IDG -2.34430 223.5 239
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Interferon regulatory factor 1 IRF1 Tbio Transcription Factor -2.90315 827.7 366
E3 SUMO-protein ligase PIAS2 PIAS2 Tbio Transcription Factor -1.84354 65.2 389
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
T-cell surface glycoprotein CD3 delta chain CD3D Tclin Non-IDG -2.41767 251.2 546