Development Level

Tchem 25 | 1,598
Tbio 23 | 11,445
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
embryonic lethality prior to t... 2 | 278
increased neutrophil cell numb... 2 | 46
abnormal anxiety-related respo... 1 | 1
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal limb morphology 1 | 13
abnormal social-conspecific in... 1 | 3
abnormal tail morphology 1 | 25
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
impaired righting response 1 | 26
increased body length 1 | 32
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased heart left ventricle... 1 | 4
increased lymphocyte cell numb... 1 | 32
mydriasis 1 | 6
respiratory system phenotype 1 | 2
short tibia 1 | 97

Disease

Cancer 48 | 2,499
Carcinoma 44 | 11,493
ovarian cancer 39 | 8,520
osteosarcoma 37 | 7,950
glioblastoma 33 | 5,792
Breast cancer 30 | 3,578
atypical teratoid / rhabdoid tumor 30 | 5,112
lung cancer 28 | 4,740
medulloblastoma, large-cell 26 | 6,241
psoriasis 26 | 6,694
invasive ductal carcinoma 25 | 2,951
non-small cell lung cancer 22 | 2,890
Astrocytoma, Pilocytic 19 | 3,081
Kidney cancer 19 | 2,613
breast carcinoma 19 | 1,638
ependymoma 19 | 4,679
ductal carcinoma in situ 18 | 1,745
group 4 medulloblastoma 18 | 1,855
malignant mesothelioma 18 | 3,232
tuberculosis 18 | 2,010
diabetes mellitus 17 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung carcinoma 17 | 2,843
adult high grade glioma 16 | 3,801
lung adenocarcinoma 16 | 2,716
pancreatic cancer 16 | 2,398
ulcerative colitis 16 | 1,819
pituitary cancer 15 | 1,972
Breast Neoplasms 14 | 445
Kidney disease 14 | 430
Schizophrenia 14 | 1,160
interstitial cystitis 14 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
primitive neuroectodermal tumor 14 | 3,035
subependymal giant cell astrocytoma 14 | 2,287
Arthritis 13 | 290
Mammary Neoplasms 13 | 425
Neoplasm Metastasis 13 | 168
Osteoporosis 13 | 363
Stomach Neoplasms 13 | 300
astrocytoma 13 | 1,146
Carcinoma, Squamous Cell 12 | 110
Lung Neoplasms 12 | 232
Obesity 12 | 678
Squamous cell carcinoma 12 | 129
group 3 medulloblastoma 12 | 4,104
oligodendroglioma 12 | 2,850
Depressive disorder 11 | 409
Neoplasm Invasiveness 11 | 161
Prostatic Neoplasms 11 | 495
Rheumatoid arthritis 11 | 1,191
Short stature 11 | 531
Vascular disease 11 | 319
adrenocortical carcinoma 11 | 1,428
Alzheimer's disease 10 | 658
Bipolar Disorder 10 | 666
Liver disease 10 | 237
Mental Depression 10 | 333
Multiple Sclerosis 10 | 540
Orbital separation excessive 10 | 244
colon cancer 10 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Asthma 9 | 385
Autosomal recessive predisposition 9 | 1,442
Byzanthine arch palate 9 | 194
Disease Models, Animal 9 | 155
astrocytic glioma 9 | 2,597
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
esophageal adenocarcinoma 9 | 737
juvenile dermatomyositis 9 | 1,187
Carcinoma, Hepatocellular 8 | 228
Concave bridge of nose 8 | 195
Cryptorchidism 8 | 296
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Down syndrome 8 | 499
Downward slant of palpebral fissure 8 | 158
Frontal bossing 8 | 157
Heart disease 8 | 306
Hypersensitivity reaction type II disease 8 | 253
Hypoplastic mandible condyle 8 | 275
Liver carcinoma 8 | 240
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Ovarian Neoplasms 8 | 102
hepatocellular carcinoma 8 | 547
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pediatric high grade glioma 8 | 1,064
primary pancreatic ductal adenocarcinoma 8 | 1,109
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Epilepsy 7 | 792
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
Poor school performance 7 | 645

Tissue

Blood and immune system 55 | 16,909
Digestive Tract 55 | 17,369
Endocrine System 55 | 18,159
Female tissues 55 | 17,400
Liver and Pancreas 55 | 16,750
Male tissues 55 | 17,142
Nervous System 55 | 16,725
Respiratory system 55 | 16,393
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 19 | 12,091
Kinase 17 | 634
Enzyme 13 | 4,145
Transcription Factor 6 | 1,400

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 19 FGF19 Tbio Non-IDG -2.54882 334.2 305
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Beta-klotho KLB Tbio Enzyme -2.02643 82.8 95
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Dual specificity protein phosphatase 6 DUSP6 Tbio Enzyme -2.22889 183.5 379
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Fibroblast growth factor 23 FGF23 Tbio Non-IDG -3.19500 1726.4 296