Development Level

Tbio 42 | 11,445
Tchem 18 | 1,598
Tclin 13 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal gait 3 | 69
embryonic lethality prior to t... 3 | 278
abnormal heart morphology 2 | 162
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
absent epididymis 1 | 3
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
hypoactivity 1 | 132
increased basophil cell number 1 | 7
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased thermal nociceptive ... 1 | 9
trunk curl 1 | 16

Disease

Carcinoma 53 | 11,493
osteosarcoma 45 | 7,950
Cancer 42 | 2,499
ovarian cancer 39 | 8,520
lung cancer 30 | 4,740
psoriasis 29 | 6,694
glioblastoma 27 | 5,792
Multiple myeloma 25 | 1,332
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
Schizophrenia 16 | 1,160
adult high grade glioma 16 | 3,801
diabetes mellitus 16 | 1,728
subependymal giant cell astrocytoma 16 | 2,287
Kidney cancer 15 | 2,613
astrocytoma 15 | 1,146
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
malignant mesothelioma 14 | 3,232
Obesity 13 | 678
Peripheral T-cell lymphoma 13 | 25
Primary cutaneous T-cell lymphoma 13 | 29
ependymoma 13 | 4,679
invasive ductal carcinoma 12 | 2,951
tuberculosis 12 | 2,010
Breast cancer 11 | 3,578
Intellectual disability 11 | 1,016
Astrocytoma, Pilocytic 10 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
non-small cell lung cancer 10 | 2,890
primitive neuroectodermal tumor 10 | 3,035
Mood Disorders 9 | 184
acute quadriplegic myopathy 9 | 1,158
group 4 medulloblastoma 9 | 1,855
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
ulcerative colitis 9 | 1,819
Pick disease 8 | 1,894
Rheumatoid arthritis 8 | 1,191
Short stature 8 | 531
Waldenstrons macroglobulinemia 8 | 765
acute myeloid leukemia 8 | 783
dermatomyositis 8 | 966
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Breast Neoplasms 7 | 445
Depressive disorder 7 | 409
Dull intelligence 7 | 645
Endometriosis 7 | 540
Inflammatory bowel disease 7 | 151
Low intelligence 7 | 645
Mammary Neoplasms 7 | 425
Mental Depression 7 | 333
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
Alzheimer's disease 6 | 658
Brain Ischemia 6 | 110
Carcinoma, Squamous Cell 6 | 110
Crohn's disease 6 | 321
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Diabetes Mellitus, Type 2 6 | 142
Frontal bossing 6 | 157
Immune system cancer 6 | 140
Kidney disease 6 | 430
Squamous cell carcinoma 6 | 129
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
medulloblastoma 6 | 720
Anemia 5 | 365
Arthritis 5 | 290
Asthma 5 | 385
Atherosclerosis 5 | 291
Bipolar Disorder 5 | 666
Bladder Neoplasm 5 | 112
Cardiomegaly 5 | 116
Cleft Palate 5 | 271
Colonic Neoplasms 5 | 142
Enophthalmos 5 | 75
Heart disease 5 | 306
Liver Cirrhosis, Experimental 5 | 769
Melanoma 5 | 711
Multiple Sclerosis 5 | 540
Muscle hypotonia 5 | 571
Parkinson's disease 5 | 392
Pneumonia 5 | 174
Prostatic Neoplasms 5 | 495
Stomach Neoplasms 5 | 300
Sunken eyes 5 | 63
Urinary Bladder Neoplasms 5 | 114
adrenocortical carcinoma 5 | 1,428
spina bifida 5 | 1,074

Tissue

Blood and immune system 73 | 16,909
Digestive Tract 73 | 17,369
Endocrine System 73 | 18,159
Female tissues 73 | 17,400
Liver and Pancreas 73 | 16,750
Male tissues 73 | 17,142
Nervous System 73 | 16,725
Respiratory system 73 | 16,393
Skin and soft tissues 73 | 17,230
Urinary Tract 73 | 16,678
Cardiovascular System 71 | 15,192

Target Family

Epigenetic 24 | 242
Non-IDG 23 | 12,091
Transcription Factor 17 | 1,400
Enzyme 7 | 4,145
Nuclear Receptor 2 | 48
Kinase 1 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
NAD-dependent protein deacylase sirtuin-5, mitochondrial SIRT5 Tchem Epigenetic -2.36015 219.3 427
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
Nuclear receptor subfamily 2 group C member 1 NR2C1 Tbio Nuclear Receptor -1.39182 24.4 294
Chromodomain-helicase-DNA-binding protein 3 CHD3 Tbio Epigenetic -1.95633 85.2 190
Peptidyl-prolyl cis-trans isomerase FKBP3 FKBP3 Tbio Enzyme -1.96885 93.5 161
Metastasis-associated protein MTA2 MTA2 Tbio Transcription Factor -1.59201 32.3 283
Methyl-CpG-binding domain protein 3-like 2 MBD3L2 Tdark Non-IDG -0.21307 2.46 61
Protein SMG5 SMG5 Tbio Non-IDG -1.02024 9.67 88