Development Level

Tbio 10 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598

IMPC Phenotype

abnormal snout morphology 1 | 23
decreased leukocyte cell numbe... 1 | 73
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123

Disease

Breast cancer 12 | 3,578
Cancer 12 | 2,499
interstitial cystitis 11 | 2,312
lung cancer 11 | 4,740
Carcinoma 9 | 11,493
psoriasis 9 | 6,694
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
pancreatic cancer 8 | 2,398
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
ovarian cancer 7 | 8,520
ulcerative colitis 7 | 1,819
Kidney cancer 6 | 2,613
Schizophrenia 6 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
spina bifida 6 | 1,074
Astrocytoma, Pilocytic 5 | 3,081
Neoplasm Metastasis 5 | 168
Prostatic Neoplasms 5 | 495
Rheumatoid arthritis 5 | 1,191
Stomach Neoplasms 5 | 300
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
group 3 medulloblastoma 5 | 4,104
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
Arthritis, Juvenile 4 | 126
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Disease Progression 4 | 136
Endometriosis 4 | 540
Gallbladder Neoplasms 4 | 10
HER2-positive carcinoma of breast 4 | 21
Juvenile arthritis 4 | 126
Lung Neoplasms 4 | 232
Major Depressive Disorder 4 | 301
Ovarian Neoplasms 4 | 102
Unipolar Depression 4 | 250
adult high grade glioma 4 | 3,801
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
gallbladder neoplasm 4 | 10
hepatocellular carcinoma 4 | 547
lung carcinoma 4 | 2,843
mucosa-associated lymphoid tissue lymphoma 4 | 484
ovarian neoplasm 4 | 99
pancreatic carcinoma 4 | 562
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Adenocarcinoma 3 | 122
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Non-Small-Cell Lung 3 | 107
Erythropoietic protoporphyria 3 | 15
Head and Neck Neoplasms 3 | 26
Liver carcinoma 3 | 240
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Melanoma 3 | 711
Mucositis 3 | 29
Neoplasm Invasiveness 3 | 161
Non-small cell lung cancer, positive for epidermal growth factor receptor expression 3 | 4
Papilloma 3 | 44
Protoporphyria, Erythropoietic 3 | 4
Pulmonary Fibrosis 3 | 106
Skin cancer 3 | 469
Vascular disease 3 | 319
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
gastric cancer 3 | 459
gastric carcinoma 3 | 807
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung carcinoma 3 | 317
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Atopic dermatitis 2 | 952
Contact Dermatitis 2 | 81
Depressive disorder 2 | 409
Dermatitis 2 | 157
Dermatitis, Contact 2 | 71
Down syndrome 2 | 499
Heart disease 2 | 306
Kidney disease 2 | 430
Mental Depression 2 | 333
Polycystic ovary syndrome 2 | 360
Reperfusion Injury 2 | 86
acute quadriplegic myopathy 2 | 1,158
nephrosclerosis 2 | 333
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 11 | 12,091
Kinase 4 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 137 | 137
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Pro-neuregulin-2, membrane-bound isoform NRG2 Tbio Non-IDG -1.46980 32.0 141
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Pro-neuregulin-3, membrane-bound isoform NRG3 Tbio Non-IDG -1.56404 39.4 165
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.15761 135.3 697
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Amphiregulin AREG Tbio Non-IDG -2.59721 307.5 389
Probetacellulin BTC Tbio Non-IDG -2.87519 736.6 299
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859