Development Level

Tbio 13 | 11,445
Tclin 7 | 613
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
abnormal femur morphology 1 | 14
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased startle reflex 1 | 112
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 20 | 11,493
ovarian cancer 18 | 8,520
osteosarcoma 17 | 7,950
Cancer 15 | 2,499
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
psoriasis 13 | 6,694
Breast cancer 11 | 3,578
ulcerative colitis 11 | 1,819
adult high grade glioma 10 | 3,801
ependymoma 9 | 4,679
lung cancer 9 | 4,740
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
diabetes mellitus 8 | 1,728
invasive ductal carcinoma 8 | 2,951
Arthritis 7 | 290
Depressive disorder 7 | 409
colon cancer 7 | 1,478
group 3 medulloblastoma 7 | 4,104
primary pancreatic ductal adenocarcinoma 7 | 1,109
Epilepsy 6 | 792
Kidney disease 6 | 430
Neoplasm Metastasis 6 | 168
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Breast Neoplasms 5 | 445
Heart disease 5 | 306
Liver Cirrhosis, Experimental 5 | 769
Mammary Neoplasms 5 | 425
Mental Depression 5 | 333
Neoplasm Invasiveness 5 | 161
Pick disease 5 | 1,894
Renal Cell Carcinoma 5 | 214
Seizures 5 | 596
Skin cancer 5 | 469
Stomach Neoplasms 5 | 300
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
Alzheimer's disease 4 | 658
Asthma 4 | 385
Big calvaria 4 | 147
Carcinoma, Squamous Cell 4 | 110
Crohn's disease 4 | 321
Disease Models, Animal 4 | 155
Dull intelligence 4 | 645
Gastrointestinal system disease 4 | 54
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Lung disease 4 | 142
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Skin Neoplasms 4 | 69
Squamous cell carcinoma 4 | 129
Substance Withdrawal Syndrome 4 | 55
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
urothelial carcinoma 4 | 318
Anemia 3 | 365
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Brain Ischemia 3 | 110
Hepatomegaly 3 | 285
Hypertension 3 | 396
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Psychotic Disorders 3 | 151
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
pediatric high grade glioma 3 | 1,064

Tissue

Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678

Target Family

Non-IDG 13 | 12,091
Kinase 8 | 634
Enzyme 2 | 4,145
GPCR 2 | 408

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Tbio Non-IDG -2.24331 158.7 195
Guanine nucleotide-binding protein subunit alpha-12 GNA12 Tbio Non-IDG -0.97325 9.11 163
Sphingosine 1-phosphate receptor 3 S1PR3 Tclin GPCR -2.25158 157.8 392
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
C-X-C chemokine receptor type 4 CXCR4 Tclin GPCR -3.41606 2525.3 1240