Development Level

Tbio 11 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 11 | 11,493
Kidney cancer 9 | 2,613
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
Autosomal recessive predisposition 8 | 1,442
Breast cancer 8 | 3,578
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
Prenatal onset 6 | 139
ependymoma 6 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
ANONYCHIA 5 | 20
Aplasia Cutis Congenita 5 | 14
Atrophic scar 5 | 18
Congenital scar 5 | 13
Death in early childhood 5 | 82
Death in infancy 5 | 82
Defective enamel matrix 5 | 35
Dental Enamel Hypoplasia 5 | 43
Dysplasia of tooth enamel 5 | 35
Dystrophia unguium 5 | 53
Epidermolysis bullosa 5 | 21
Junctional split 5 | 6
Milium Cyst 5 | 16
Nail dysplasia 5 | 52
Oral mucosal blistering 5 | 10
Thin dental enamel 5 | 35
active ulcerative colitis 5 | 764
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
medulloblastoma, large-cell 5 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
psoriasis 5 | 6,694
Abnormal pigmentation 4 | 25
Adult junctional epidermolysis bullosa (disorder) 4 | 5
Anemia 4 | 365
Astrocytoma, Pilocytic 4 | 3,081
Dehydration 4 | 40
Dental caries 4 | 164
Duchenne muscular dystrophy 4 | 601
Epidermolysis Bullosa, Junctional 4 | 4
Epidermolysis Bullosa, Junctional, Non-Herlitz Type 4 | 5
Failure to gain weight 4 | 365
Flexion contracture of proximal interphalangeal joint 4 | 75
Fragile nails 4 | 16
Hemoglobin low 4 | 124
Hypodontia 4 | 81
Junctional epidermolysis bullosa 4 | 7
Liver cancer 4 | 604
Myopia 4 | 176
Palmar hyperhidrosis 4 | 5
Pediatric failure to thrive 4 | 365
Plantar hyperkeratosis 4 | 7
Rotting teeth 4 | 73
Scarring alopecia of scalp 4 | 13
Skin Erosion 4 | 12
Sparse body hair 4 | 32
atypical teratoid / rhabdoid tumor 4 | 5,112
esophageal adenocarcinoma 4 | 737
lung adenocarcinoma 4 | 2,716
primary pancreatic ductal adenocarcinoma 4 | 1,109
Abnormal blistering of the skin 3 | 54
Adult junctional epidermolysis bullosa 3 | 3
Age related macular degeneration 1 3 | 4
Barrett's esophagus 3 | 182
Blister of skin 3 | 54
Cancer 3 | 2,499
Congenital localized absence of skin 3 | 6
Dyspnea 3 | 76
Esophageal Stenosis 3 | 15
Feeding difficulties 3 | 127
Generalized junctional epidermolysis bullosa, non-Herlitz type 3 | 3
Herlitz Disease 3 | 3
Hoarseness 3 | 31
Laryngismus 3 | 3
Laryngostenosis 3 | 10
Melanoma 3 | 711
Muscle hypotonia 3 | 571
Paronychia Inflammation 3 | 9
Pierson syndrome 3 | 13
Pyloric Stenosis 3 | 47
Skin bulla 3 | 54
Wounds and Injuries 3 | 18
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
osteosarcoma 3 | 7,950
Epilepsy 2 | 792
pediatric high grade glioma 2 | 1,064
tuberculosis 2 | 2,010

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 11 | 12,091

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
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http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
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http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
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http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.09168 112.5 175
Laminin subunit beta-3 LAMB3 Tbio Non-IDG -2.07156 116.4 170
Integrin alpha-6 ITGA6 Tbio Non-IDG -2.30127 180.4 944
Laminin subunit alpha-5 LAMA5 Tbio Non-IDG -1.43472 26.4 217
Laminin subunit alpha-1 LAMA1 Tbio Non-IDG -1.97342 92.5 215
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.53347 339.4 135
Laminin subunit beta-2 LAMB2 Tbio Non-IDG -2.14401 131.7 230
Laminin subunit alpha-3 LAMA3 Tbio Non-IDG -2.53686 344.3 110