Development Level

Tbio 27 | 11,445
Tchem 10 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
decreased mean corpuscular vol... 3 | 79
preweaning lethality, incomple... 3 | 499
decreased bone mineral content 2 | 151
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased startle reflex 2 | 112
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
thrombocytopenia 1 | 56
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 36 | 11,493
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 26 | 5,792
osteosarcoma 26 | 7,950
ovarian cancer 26 | 8,520
medulloblastoma, large-cell 25 | 6,241
psoriasis 21 | 6,694
Cancer 20 | 2,499
ependymoma 19 | 4,679
lung cancer 17 | 4,740
adult high grade glioma 16 | 3,801
Kidney cancer 15 | 2,613
lung carcinoma 15 | 2,843
primitive neuroectodermal tumor 15 | 3,035
oligodendroglioma 14 | 2,850
Astrocytoma, Pilocytic 13 | 3,081
group 3 medulloblastoma 13 | 4,104
Breast cancer 12 | 3,578
invasive ductal carcinoma 12 | 2,951
Pick disease 10 | 1,894
astrocytic glioma 10 | 2,597
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
tuberculosis 9 | 2,010
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
diabetes mellitus 8 | 1,728
subependymal giant cell astrocytoma 8 | 2,287
ulcerative colitis 8 | 1,819
Autosomal recessive predisposition 7 | 1,442
Hypertension 7 | 396
Liver Cirrhosis, Experimental 7 | 769
interstitial cystitis 7 | 2,312
Intellectual disability 6 | 1,016
cystic fibrosis 6 | 1,696
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
malignant mesothelioma 6 | 3,232
primary pancreatic ductal adenocarcinoma 6 | 1,109
Depressive disorder 5 | 409
Epilepsy 5 | 792
Impotence 5 | 42
Stomach Neoplasms 5 | 300
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
Atherosclerosis 4 | 291
Attention deficit hyperactivity disorder 4 | 278
Breast Neoplasms 4 | 445
Cerebrovascular disease 4 | 238
Coronary artery disease 4 | 268
Crohn's disease 4 | 321
Dull intelligence 4 | 645
Glaucoma 4 | 239
Heart disease 4 | 306
Kidney disease 4 | 430
Liver Cirrhosis 4 | 181
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Muscle hypotonia 4 | 571
Poor school performance 4 | 645
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
pituitary cancer 4 | 1,972
Alzheimer's disease 3 | 658
Bipolar Disorder 3 | 666
Cardiovascular system disease 3 | 246
Cerebrovascular accident 3 | 63
Duchenne muscular dystrophy 3 | 601
Hyperreflexia 3 | 209
Large intestine cancer 3 | 126
Liver cancer 3 | 604
Lung disease 3 | 142
Major Depressive Disorder 3 | 301
Neurodegenerative disease 3 | 414
Prostatic Neoplasms 3 | 495
Proteinuria 3 | 144
Skin cancer 3 | 469
Unipolar Depression 3 | 250
esophageal adenocarcinoma 3 | 737
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
progressive supranuclear palsy 3 | 676

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Female tissues 42 | 17,400
Nervous System 42 | 16,725
Urinary Tract 42 | 16,678
Cardiovascular System 41 | 15,192
Respiratory system 40 | 16,393

Target Family

Non-IDG 23 | 12,091
Kinase 10 | 634
Enzyme 7 | 4,145
GPCR 2 | 408
Ion Channel 1 | 344

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Rho GDP-dissociation inhibitor 1 ARHGDIA Tchem Non-IDG -2.56885 370.1 382
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 PLCB3 Tbio Enzyme -1.88444 66.2 265
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435