Development Level

Tbio 25 | 11,445
Tclin 11 | 613
Tchem 7 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal heart morphology 2 | 162
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal ovary morphology 1 | 7
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
absent epididymis 1 | 3
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased grip strength 1 | 41
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 33 | 11,493
osteosarcoma 28 | 7,950
ovarian cancer 25 | 8,520
Cancer 22 | 2,499
psoriasis 21 | 6,694
Multiple myeloma 19 | 1,332
medulloblastoma, large-cell 19 | 6,241
atypical teratoid / rhabdoid tumor 17 | 5,112
glioblastoma 16 | 5,792
lung cancer 15 | 4,740
Breast cancer 13 | 3,578
malignant mesothelioma 13 | 3,232
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
invasive ductal carcinoma 12 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Primary cutaneous T-cell lymphoma 10 | 29
adult high grade glioma 10 | 3,801
primitive neuroectodermal tumor 10 | 3,035
Kidney cancer 9 | 2,613
Peripheral T-cell lymphoma 9 | 25
astrocytic glioma 9 | 2,597
breast carcinoma 9 | 1,638
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
Depressive disorder 8 | 409
Mental Depression 8 | 333
Pick disease 8 | 1,894
dermatomyositis 8 | 966
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung carcinoma 7 | 2,843
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
Intellectual disability 6 | 1,016
Muscle hypotonia 6 | 571
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
acute quadriplegic myopathy 6 | 1,158
cystic fibrosis 6 | 1,696
juvenile dermatomyositis 6 | 1,187
pituitary cancer 6 | 1,972
Bipolar Disorder 5 | 666
Cocaine-Related Disorders 5 | 92
Epilepsy 5 | 792
Seizures 5 | 596
Unipolar Depression 5 | 250
Vascular disease 5 | 319
active ulcerative colitis 5 | 764
colon cancer 5 | 1,478
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Amyotrophic lateral sclerosis 4 | 451
Cleft Palate 4 | 271
Dull intelligence 4 | 645
Immune system cancer 4 | 140
Leukemia, Myelocytic, Acute 4 | 120
Low intelligence 4 | 645
Low set ears 4 | 181
Major Depressive Disorder 4 | 301
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Mood Disorders 4 | 184
Osteoporosis 4 | 363
Poor school performance 4 | 645
Short stature 4 | 531
adrenocortical carcinoma 4 | 1,428
diabetes mellitus 4 | 1,728
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
ulcerative colitis 4 | 1,819
Anteverted nostril 3 | 191
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Cognitive delay 3 | 608
Contact Dermatitis 3 | 81
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Frontal bossing 3 | 157
Global developmental delay 3 | 608
Leukemia 3 | 104
Lupus erythematosus 3 | 57
Malaria 3 | 160
Mental and motor retardation 3 | 608
Neurodegenerative disease 3 | 414
Prostatic Neoplasms 3 | 495
Short nose 3 | 132
Small nose 3 | 132
Upward slant of palpebral fissure 3 | 75
active Crohn's disease 3 | 922
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 21 | 12,091
Epigenetic 8 | 242
Transcription Factor 6 | 1,400
Enzyme 3 | 4,145
Kinase 3 | 634
Nuclear Receptor 2 | 48

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.84078 65.7 254
Nuclear pore complex protein Nup153 NUP153 Tbio Non-IDG -2.14396 129.9 100
Nuclear pore complex protein Nup214 NUP214 Tbio Non-IDG -2.25062 166.6 35
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620
Ankyrin repeat family A protein 2 ANKRA2 Tbio Non-IDG -0.53092 4.21 117
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135
BCL-6 corepressor BCOR Tbio Non-IDG -2.04681 115.7 157
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101