Development Level

Tbio 13 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

decreased fasted circulating g... 2 | 65
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
decreased circulating fructosa... 1 | 30
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15

Disease

Carcinoma 14 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
psoriasis 12 | 6,694
glioblastoma 10 | 5,792
Cancer 9 | 2,499
group 3 medulloblastoma 7 | 4,104
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
lung cancer 6 | 4,740
Kidney cancer 5 | 2,613
Waldenstrons macroglobulinemia 5 | 765
subependymal giant cell astrocytoma 5 | 2,287
Astrocytoma, Pilocytic 4 | 3,081
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
dermatomyositis 4 | 966
malignant mesothelioma 4 | 3,232
Amyotrophic lateral sclerosis 3 | 451
Cocaine-Related Disorders 3 | 92
Craniofacial Abnormalities 3 | 151
Disease Models, Animal 3 | 155
Gastrointestinal system disease 3 | 54
Kidney disease 3 | 430
Multiple myeloma 3 | 1,332
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Acquired flat foot 2 | 72
Acquired immunodeficiency syndrome 2 | 197
Arthritis 2 | 290
Arthritis, Juvenile 2 | 126
Asthma 2 | 385
Brain Ischemia 2 | 110
CEROID LIPOFUSCINOSIS, NEURONAL, 6 2 | 6
Carcinoma, Squamous Cell 2 | 110
Cardiomyopathies 2 | 110
Cholestasis, Extrahepatic 2 | 25
Congenital Camptodactyly 2 | 40
Dull intelligence 2 | 645
Enophthalmos 2 | 75
Female infertility 2 | 30
Flatfoot 2 | 73
Gliosis 2 | 56
Head and Neck Neoplasms 2 | 26
Heart disease 2 | 306
Hyperalgesia 2 | 83
Hypertrophy 2 | 17
Increase in blood pressure 2 | 119
Infertility, Female 2 | 28
Intrauterine retardation 2 | 176
Juvenile arthritis 2 | 126
Kidney Neoplasm 2 | 29
Kidney Neoplasms 2 | 37
Liver Cirrhosis, Experimental 2 | 769
Liver Neoplasms, Experimental 2 | 59
Liver disease 2 | 237
Lung Neoplasms 2 | 232
Mental deficiency 2 | 645
Multiple Sclerosis 2 | 540
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Nerve Degeneration 2 | 121
Osteoarthritis 2 | 184
Ovarian Neoplasms 2 | 102
Pneumonia 2 | 174
Pneumonia, Pneumococcal 2 | 6
Poor school performance 2 | 645
Pulmonary Fibrosis 2 | 106
Radiation Injuries, Experimental 2 | 11
Schizophrenia 2 | 1,160
Sepsis 2 | 24
Squamous cell carcinoma 2 | 129
Streptococcal pneumonia 2 | 6
Substance Withdrawal Syndrome 2 | 55
Sunken eyes 2 | 63
Systemic scleroderma 2 | 60
Thin upper lip vermilion 2 | 67
Trigeminal Neuralgia 2 | 24
astrocytic glioma 2 | 2,597
atypical teratoid/rhabdoid tumor 2 | 357
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
non-small cell lung cancer 2 | 2,890
ovarian neoplasm 2 | 99
pancreatic cancer 2 | 2,398

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 4 | 4,145
Transcription Factor 4 | 1,400
Kinase 3 | 634

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transforming growth factor-beta receptor-associated protein 1 TGFBRAP1 Tbio Non-IDG -1.03126 9.10 179
CTD small phosphatase-like protein CTDSPL Tbio Enzyme -2.17507 152.7 141
Nuclear pore complex protein Nup214 NUP214 Tbio Non-IDG -2.25062 166.6 35
Nuclear pore complex protein Nup153 NUP153 Tbio Non-IDG -2.14396 129.9 100
Mitogen-activated protein kinase kinase kinase 1 MAP3K1 Tchem Kinase -2.12399 119.4 334
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
SUMO-conjugating enzyme UBC9 UBE2I Tbio Non-IDG -2.45979 267.1 368
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Importin subunit alpha-1 KPNA2 Tbio Non-IDG -1.90187 84.5 281
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174