Development Level

Tbio 17 | 11,445
Tchem 9 | 1,598
Tclin 6 | 613

IMPC Phenotype

embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal retina morphology 2 | 71
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 25 | 11,493
Cancer 23 | 2,499
glioblastoma 20 | 5,792
ovarian cancer 20 | 8,520
lung cancer 18 | 4,740
Breast cancer 16 | 3,578
osteosarcoma 15 | 7,950
Schizophrenia 13 | 1,160
atypical teratoid / rhabdoid tumor 13 | 5,112
diabetes mellitus 13 | 1,728
interstitial cystitis 13 | 2,312
invasive ductal carcinoma 13 | 2,951
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
pancreatic cancer 13 | 2,398
Kidney cancer 12 | 2,613
cystic fibrosis 11 | 1,696
ependymoma 11 | 4,679
medulloblastoma, large-cell 11 | 6,241
non-small cell lung cancer 11 | 2,890
primary pancreatic ductal adenocarcinoma 11 | 1,109
psoriasis 11 | 6,694
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
Neoplasm Invasiveness 9 | 161
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
Astrocytoma, Pilocytic 8 | 3,081
Kidney disease 8 | 430
Liver Cirrhosis, Experimental 8 | 769
colon cancer 8 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
oligodendroglioma 8 | 2,850
Arthritis 7 | 290
Atherosclerosis 7 | 291
Autosomal recessive predisposition 7 | 1,442
Cerebrovascular disease 7 | 238
adrenocortical carcinoma 7 | 1,428
adult high grade glioma 7 | 3,801
gastric carcinoma 7 | 807
group 3 medulloblastoma 7 | 4,104
mucosa-associated lymphoid tissue lymphoma 7 | 484
Breast Neoplasms 6 | 445
Coronary artery disease 6 | 268
Duchenne muscular dystrophy 6 | 601
Endometriosis 6 | 540
Heart disease 6 | 306
Hypertension 6 | 396
Mammary Neoplasms 6 | 425
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,146
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
non-small cell lung carcinoma 6 | 317
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Asthma 5 | 385
Atopic dermatitis 5 | 952
Carcinoma, Hepatocellular 5 | 228
Carcinoma, Squamous Cell 5 | 110
Cell Transformation, Neoplastic 5 | 97
Hypersensitivity reaction type II disease 5 | 253
Liver carcinoma 5 | 240
Lung disease 5 | 142
Multiple Sclerosis 5 | 540
Neoplasm Metastasis 5 | 168
Neoplastic Cell Transformation 5 | 89
Pulmonary Fibrosis 5 | 106
Squamous cell carcinoma 5 | 129
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
cutaneous lupus erythematosus 5 | 1,057
interstitial lung disease 5 | 298
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
primary Sjogren syndrome 5 | 735
Alzheimer's disease 4 | 658
Cardiovascular system disease 4 | 246
Down syndrome 4 | 499
Eye disease 4 | 62
Hypertensive disease 4 | 292
Infantile onset 4 | 238
Melanoma 4 | 711
Mesothelioma, Malignant 4 | 105
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Pick disease 4 | 1,894
Reperfusion Injury 4 | 86
Rheumatoid arthritis 4 | 1,191
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
dermatomyositis 4 | 966
periodontitis 4 | 293
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 468

Tissue

Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Skin and soft tissues 32 | 17,230
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Urinary Tract 31 | 16,678
Female tissues 30 | 17,400
Respiratory system 30 | 16,393
Blood and immune system 29 | 16,909
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 6 | 4,145
Kinase 4 | 634
GPCR 2 | 408

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Disintegrin and metalloproteinase domain-containing protein 12 ADAM12 Tchem Enzyme -2.28901 214.1 347
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Tenascin TNC Tbio Non-IDG -2.34421 216.5 642
Prothrombin F2 Tclin Enzyme -4.53745 33691.4 579
Alpha-actinin-1 ACTN1 Tbio Non-IDG -1.78806 54.6 318
Integrin alpha-5 ITGA5 Tbio Non-IDG -2.29130 169.1 826