Development Level

Tbio 41 | 11,445
Tchem 15 | 1,598
Tclin 6 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
decreased circulating glucose ... 3 | 126
decreased lean body mass 3 | 135
embryonic lethality prior to o... 3 | 239
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased circulating choleste... 2 | 93
decreased circulating triglyce... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal body wall morphology 1 | 9
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating creatine... 1 | 4
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lumbar vertebrae num... 1 | 2
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased sacral vertebrae num... 1 | 1
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lumbar vertebrae num... 1 | 1
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased sacral vertebrae num... 1 | 1
increased startle reflex 1 | 112
increased vertical activity 1 | 24
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
premature death 1 | 5
protruding tongue 1 | 3
small kidney 1 | 16
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 44 | 11,493
ovarian cancer 44 | 8,520
Cancer 33 | 2,499
osteosarcoma 32 | 7,950
lung cancer 31 | 4,740
glioblastoma 28 | 5,792
psoriasis 27 | 6,694
medulloblastoma, large-cell 26 | 6,241
atypical teratoid / rhabdoid tumor 23 | 5,112
malignant mesothelioma 22 | 3,232
Breast cancer 21 | 3,578
Kidney cancer 19 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
group 3 medulloblastoma 17 | 4,104
ependymoma 16 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
astrocytoma 15 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
oligodendroglioma 15 | 2,850
acute quadriplegic myopathy 14 | 1,158
pituitary cancer 14 | 1,972
primitive neuroectodermal tumor 14 | 3,035
subependymal giant cell astrocytoma 14 | 2,287
Breast Neoplasms 13 | 445
Mammary Neoplasms 13 | 425
Multiple myeloma 13 | 1,332
Schizophrenia 12 | 1,160
breast carcinoma 12 | 1,638
lung carcinoma 12 | 2,843
Astrocytoma, Pilocytic 11 | 3,081
Autosomal recessive predisposition 11 | 1,442
Endometriosis 11 | 540
Obesity 11 | 678
Prostatic Neoplasms 11 | 495
Rheumatoid arthritis 11 | 1,191
Vascular disease 11 | 319
adult high grade glioma 11 | 3,801
invasive ductal carcinoma 11 | 2,951
Waldenstrons macroglobulinemia 10 | 765
astrocytic glioma 10 | 2,597
diabetes mellitus 10 | 1,728
group 4 medulloblastoma 10 | 1,855
pancreatic cancer 10 | 2,398
Adenocarcinoma 9 | 122
Mammary Neoplasms, Experimental 9 | 154
Carcinoma, Hepatocellular 8 | 228
Liver carcinoma 8 | 240
juvenile dermatomyositis 8 | 1,187
Amyotrophic lateral sclerosis 7 | 451
Animal Mammary Neoplasms 7 | 136
Bipolar Disorder 7 | 666
Colorectal Neoplasms 7 | 243
Mammary Neoplasms, Animal 7 | 136
Pick disease 7 | 1,894
ductal carcinoma in situ 7 | 1,745
non-small cell lung cancer 7 | 2,890
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819
Adenoma 6 | 167
Alzheimer's disease 6 | 658
Anemia 6 | 365
Bladder Neoplasm 6 | 112
Cell Transformation, Neoplastic 6 | 97
Endometrial Neoplasms 6 | 55
Liver neoplasms 6 | 130
Lung Neoplasms 6 | 232
Neoplastic Cell Transformation 6 | 89
Stomach Neoplasms 6 | 300
Urinary Bladder Neoplasms 6 | 114
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
dermatomyositis 6 | 966
gastric carcinoma 6 | 807
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
non primary Sjogren syndrome sicca 6 | 891
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
Carcinoma, Squamous Cell 5 | 110
Colonic Neoplasms 5 | 142
Crohn's disease 5 | 321
Down syndrome 5 | 499
Endometrial cancer 5 | 311
Fatty Liver 5 | 70
Female infertility 5 | 30
Infertility 5 | 188
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Neurodegenerative disease 5 | 414
Small head 5 | 374
Squamous cell carcinoma 5 | 129
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
tuberculosis 5 | 2,010
Chronic Lymphocytic Leukemia 4 | 262
Male infertility 4 | 206
Mental Depression 4 | 333

Tissue

Endocrine System 65 | 18,159
Female tissues 64 | 17,400
Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Skin and soft tissues 63 | 17,230
Liver and Pancreas 62 | 16,750
Male tissues 62 | 17,142
Nervous System 62 | 16,725
Urinary Tract 61 | 16,678
Respiratory system 60 | 16,393
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 30 | 12,091
Transcription Factor 13 | 1,400
Enzyme 9 | 4,145
Epigenetic 5 | 242
Nuclear Receptor 5 | 48
Kinase 1 | 634
TF/Epigenetic 1 | 38
Transporter 1 | 473

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Steroid receptor RNA activator 1 SRA1 Tbio Non-IDG -2.78991 595.4 160
Tripartite motif-containing protein 59 TRIM59 Tbio Non-IDG -0.95825 14.1 122
POU domain, class 4, transcription factor 2 POU4F2 Tbio Transcription Factor -1.94397 90.2 145
Acidic leucine-rich nuclear phosphoprotein 32 family member A ANP32A Tbio Non-IDG -2.16099 153.6 382
POU domain, class 4, transcription factor 1 POU4F1 Tbio Transcription Factor -2.19846 154.8 107
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Nuclear receptor subfamily 0 group B member 1 NR0B1 Tbio Nuclear Receptor -2.73235 544.8 477