Development Level

Tbio 17 | 11,445
Tchem 9 | 1,598
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased spleen weight 1 | 10
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
prolonged ST segment 1 | 36
thin ventricular wall 1 | 24

Disease

Carcinoma 23 | 11,493
Cancer 22 | 2,499
osteosarcoma 21 | 7,950
ovarian cancer 17 | 8,520
glioblastoma 15 | 5,792
atypical teratoid / rhabdoid tumor 14 | 5,112
Breast cancer 13 | 3,578
psoriasis 13 | 6,694
Kidney cancer 12 | 2,613
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
ependymoma 11 | 4,679
Astrocytoma, Pilocytic 10 | 3,081
invasive ductal carcinoma 10 | 2,951
non-small cell lung cancer 10 | 2,890
adult high grade glioma 9 | 3,801
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
Carcinoma, Hepatocellular 6 | 228
Kidney disease 6 | 430
Liver carcinoma 6 | 240
Schizophrenia 6 | 1,160
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
Breast Neoplasms 5 | 445
Dilated ventricles (finding) 5 | 121
Hypodontia 5 | 81
Mammary Neoplasms 5 | 425
Neoplasm Invasiveness 5 | 161
Osteoporosis 5 | 363
Small head 5 | 374
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Cell Transformation, Neoplastic 4 | 97
Cleft Palate 4 | 271
Colorectal Neoplasms 4 | 243
Depressive disorder 4 | 409
Endometrial cancer 4 | 311
Endometriosis 4 | 540
Failure to gain weight 4 | 365
Hypoplastic mandible condyle 4 | 275
Intellectual disability 4 | 1,016
Large auricle 4 | 87
Large dysplastic ears 4 | 87
Large pinnae 4 | 87
Large prominent ears 4 | 87
Large protruding ears 4 | 87
Large, floppy ears 4 | 87
Liver Cirrhosis, Experimental 4 | 769
Macrotia 4 | 87
Mammary Neoplasms, Experimental 4 | 154
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Multiple, subcutaneous nodules 4 | 53
Muscle hypotonia 4 | 571
Neoplasm Metastasis 4 | 168
Neoplastic Cell Transformation 4 | 89
Pediatric failure to thrive 4 | 365
Prostatic Neoplasms 4 | 495
Renal Cell Carcinoma 4 | 214
Rheumatoid arthritis 4 | 1,191
Sensorineural Hearing Loss (disorder) 4 | 284
Stomach Neoplasms 4 | 300
Subcutaneous nodule 4 | 53
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Adenoma 3 | 167
Arthritis 3 | 290
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Curvature of spine 3 | 282
Disease Progression 3 | 136
Epilepsy 3 | 792
Hepatomegaly 3 | 285
Nasal bridge wide 3 | 236
Pick disease 3 | 1,894
Seizures 3 | 596
Strabismus 3 | 270
hepatocellular carcinoma 3 | 547
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Blood and immune system 29 | 16,909
Cardiovascular System 29 | 15,192
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678

Target Family

Non-IDG 18 | 12,091
Enzyme 6 | 4,145
Kinase 6 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Ras-related protein Rap-1b RAP1B Tbio Enzyme -2.38904 417.6 114
Rap guanine nucleotide exchange factor 1 RAPGEF1 Tbio Non-IDG -2.41980 281.2 167
Receptor-type tyrosine-protein phosphatase mu PTPRM Tchem Enzyme -1.84748 71.7 144
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Cadherin-1 CDH1 Tbio Non-IDG -3.85201 6324.3 1880
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Afadin AFDN Tbio Non-IDG -2.16280 151.2 200