Development Level

Tchem 10 | 1,598
Tclin 9 | 613
Tbio 7 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 25 | 11,493
Cancer 18 | 2,499
ovarian cancer 18 | 8,520
osteosarcoma 16 | 7,950
Kidney cancer 14 | 2,613
glioblastoma 14 | 5,792
psoriasis 13 | 6,694
Blastic phase chronic myeloid leukemia 11 | 58
Chronic Myelocytic Leukemia Accelerated Phase 11 | 59
atypical teratoid / rhabdoid tumor 11 | 5,112
lung cancer 11 | 4,740
Breast cancer 10 | 3,578
interstitial cystitis 10 | 2,312
medulloblastoma, large-cell 10 | 6,241
Chronic phase chronic myeloid leukemia 9 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 9 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 9 | 47
group 4 medulloblastoma 9 | 1,855
diabetes mellitus 8 | 1,728
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
cystic fibrosis 7 | 1,696
ependymoma 7 | 4,679
juvenile dermatomyositis 7 | 1,187
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Astrocytoma, Pilocytic 6 | 3,081
Liver Cirrhosis, Experimental 6 | 769
Schizophrenia 6 | 1,160
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
Autosomal recessive predisposition 5 | 1,442
Pick disease 5 | 1,894
adult high grade glioma 5 | 3,801
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
subependymal giant cell astrocytoma 5 | 2,287
Chronic Lymphocytic Leukemia 4 | 262
Craniofrontonasal syndrome 4 | 13
Heart disease 4 | 306
Obesity 4 | 678
Stomach Neoplasms 4 | 300
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
dermatomyositis 4 | 966
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Anemia 3 | 365
Arthritis 3 | 290
Attention deficit hyperactivity disorder 3 | 278
Breast Neoplasms 3 | 445
Byzanthine arch palate 3 | 194
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Curvature of spine 3 | 282
Depressive disorder 3 | 409
Downward slant of palpebral fissure 3 | 158
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Failure to gain weight 3 | 365
Frontal bossing 3 | 157
Gastrointestinal Hemorrhage 3 | 52
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Joint laxity 3 | 54
Kidney disease 3 | 430
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Orbital separation excessive 3 | 244
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Sensorineural Hearing Loss (disorder) 3 | 284
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
mucosa-associated lymphoid tissue lymphoma 3 | 484
pituitary cancer 3 | 1,972
Hemoglobin low 2 | 124

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Kinase 16 | 634
Non-IDG 8 | 12,091
Enzyme 2 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ephrin type-B receptor 4 EPHB4 Tchem Kinase -2.26622 206.3 514
Ephrin type-B receptor 1 EPHB1 Tchem Kinase -1.70013 52.0 389
Tyrosine-protein kinase Blk BLK Tchem Kinase -1.88753 81.6 418
Ephrin-B1 EFNB1 Tbio Non-IDG -2.26015 197.6 359
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.23001 181.6 129
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Dynamin-1 DNM1 Tbio Non-IDG -2.67692 450.0 464
Tyrosine-protein kinase HCK HCK Tclin Kinase -3.53517 3192.7 428
Integrin alpha-IIb ITGA2B Tclin Non-IDG -3.52120 3309.8 1170
Tyrosine-protein kinase Fgr FGR Tchem Kinase -2.37977 226.9 400