Development Level

Tbio 25 | 11,445
Tclin 10 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 2 | 298
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
thrombocytopenia 2 | 56
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal male genitalia morpho... 1 | 3
abnormal skin morphology 1 | 50
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
polysyndactyly 1 | 2
short tibia 1 | 97
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 29 | 11,493
osteosarcoma 25 | 7,950
ovarian cancer 22 | 8,520
Cancer 18 | 2,499
glioblastoma 18 | 5,792
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
psoriasis 15 | 6,694
malignant mesothelioma 14 | 3,232
ependymoma 13 | 4,679
group 3 medulloblastoma 13 | 4,104
Breast cancer 12 | 3,578
non-small cell lung cancer 12 | 2,890
Kidney cancer 11 | 2,613
lung carcinoma 11 | 2,843
tuberculosis 10 | 2,010
colon cancer 9 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
adult high grade glioma 8 | 3,801
astrocytic glioma 8 | 2,597
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
ulcerative colitis 8 | 1,819
Liver Cirrhosis, Experimental 7 | 769
ductal carcinoma in situ 7 | 1,745
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
Neoplasm Metastasis 6 | 168
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
spina bifida 6 | 1,074
Neoplasm Invasiveness 5 | 161
Schizophrenia 5 | 1,160
Skin cancer 5 | 469
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 364
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Cerebrovascular accident 4 | 63
Coronary artery disease 4 | 268
Heart disease 4 | 306
Kidney disease 4 | 430
Liver carcinoma 4 | 240
Lung Neoplasms 4 | 232
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Stomach Neoplasms 4 | 300
juvenile dermatomyositis 4 | 1,187
Adenocarcinoma 3 | 122
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Squamous Cell 3 | 110
Cell Transformation, Neoplastic 3 | 97
Cerebrovascular disease 3 | 238
Disease Progression 3 | 136
Major Depressive Disorder 3 | 301
McCune Albright syndrome 3 | 19
Mesothelioma, Malignant 3 | 105
Polycystic ovary syndrome 3 | 360
Squamous cell carcinoma 3 | 129
Unipolar Depression 3 | 250
Vascular disease 3 | 319
esophageal adenocarcinoma 3 | 737
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
Autoimmune thrombocytopenic purpura 2 | 13
Cardiomyopathies 2 | 110
Colorectal Neoplasms 2 | 243
Congenital Heart Defects 2 | 58
Constipation 2 | 181
Craniofacial Abnormalities 2 | 151
Ecchymosis 2 | 66
Epistaxis 2 | 43
Gingival Hemorrhage 2 | 18
Heart Defects, Congenital 2 | 37
Intracranial Hemorrhages 2 | 16
Isolated cases 2 | 72
Kidney Diseases 2 | 114
Myocardial Infarction 2 | 151
Nonsyndromic deafness 2 | 142
Purpura 2 | 43
Thrombocytopenia 2 | 197
facioscapulohumeral dystrophy 2 | 288

Tissue

Cardiovascular System 36 | 15,192
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 34 | 16,393

Target Family

Non-IDG 23 | 12,091
Kinase 5 | 634
Enzyme 4 | 4,145
GPCR 4 | 408

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
ARF GTPase-activating protein GIT1 GIT1 Tbio Enzyme -1.84352 75.7 358
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
PH and SEC7 domain-containing protein 1 PSD Tbio Non-IDG -2.13025 139.8 20
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 ARAP2 Tbio Non-IDG -1.62695 41.0 74
IQ motif and SEC7 domain-containing protein 1 IQSEC1 Tbio Non-IDG -1.04789 14.7 28
Ubiquitin carboxyl-terminal hydrolase 6 USP6 Tbio Enzyme -1.93358 81.9 169
PTB domain-containing engulfment adapter protein 1 GULP1 Tbio Non-IDG -1.84615 71.1 139
Cytohesin-3 CYTH3 Tbio Non-IDG -1.83094 69.1 156