Development Level

Tbio 25 | 11,445
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
decreased caudal vertebrae num... 1 | 53

Disease

Carcinoma 21 | 11,493
ovarian cancer 16 | 8,520
osteosarcoma 15 | 7,950
psoriasis 12 | 6,694
glioblastoma 10 | 5,792
Multiple myeloma 9 | 1,332
atypical teratoid / rhabdoid tumor 8 | 5,112
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
ependymoma 7 | 4,679
Breast cancer 6 | 3,578
Rheumatoid arthritis 6 | 1,191
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
breast carcinoma 5 | 1,638
dermatomyositis 5 | 966
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Kidney cancer 4 | 2,613
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
malignant mesothelioma 4 | 3,232
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
Duchenne muscular dystrophy 3 | 601
acute myeloid leukemia 3 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Cancer 2 | 2,499
Cell Transformation, Neoplastic 2 | 97
Gaucher disease type 1 2 | 180
Hypertrophy of breast 2 | 17
Leber congenital amaurosis 2 | 69
Lung disease 2 | 142
Periventricular nodular heterotopia 2 | 30
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
hereditary spastic paraplegia 2 | 318
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sarcoidosis 2 | 370
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Amyotrophic lateral sclerosis 1 | 451
Arsenic Poisoning 1 | 62
Autoimmune Diseases 1 | 67
Bladder Neoplasm 1 | 112
Breast Neoplasms 1 | 445
Clubfoot 1 | 39
Dermatologic disorders 1 | 93
Difficulty walking 1 | 28
Dysarthria 1 | 192
Heart conduction disease 1 | 83
Heart failure 1 | 162
Isolated growth hormone deficiency type II 1 | 4
Liver diseases 1 | 87
Lymphopenia 1 | 67
Myoclonic Epilepsies, Progressive 1 | 44
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Nervous System Diseases 1 | 53
Pain agnosia 1 | 104
Progressive disorder 1 | 142
Reflex, Deep Tendon, Absent 1 | 92
Shwachman-Diamond syndrome 1 | 17
Skin Diseases 1 | 71
Skin cancer 1 | 469
Teratocarcinoma 1 | 8
Tremor 1 | 113
Urinary Bladder Neoplasms 1 | 114
cystic fibrosis and chronic rhinosinusitis 1 | 214
interstitial lung disease 1 | 298
nervous system disorder 1 | 53
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678

Target Family

Non-IDG 20 | 12,091
Enzyme 7 | 4,145
Kinase 1 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 ASAP1 Tbio Non-IDG -1.76454 62.6 183
ARF GTPase-activating protein GIT1 GIT1 Tbio Enzyme -1.84352 75.7 358
Actin-related protein 2 ACTR2 Tbio Non-IDG -1.88412 78.5 211
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 ARFGEF1 Tbio Non-IDG -0.85174 8.71 57
Rho GTPase-activating protein 10 ARHGAP10 Tbio Enzyme -1.35140 20.2 78
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 GBF1 Tbio Non-IDG -0.60758 4.31 61
Cytohesin-1 CYTH1 Tbio Non-IDG -2.10475 140.2 194
Clathrin light chain A CLTA Tbio Non-IDG -1.32676 16.0 244
Clathrin light chain B CLTB Tbio Non-IDG -2.29105 193.6 153
Phospholipase D2 PLD2 Tchem Enzyme -2.47197 312.2 172