Development Level

Tbio 11 | 11,445
Tclin 10 | 613
Tchem 5 | 1,598

IMPC Phenotype

decreased total body fat amoun... 2 | 207
increased neutrophil cell numb... 2 | 46
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased circulating glucose ... 1 | 126
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

psoriasis 19 | 6,694
Cancer 18 | 2,499
osteosarcoma 17 | 7,950
Carcinoma 16 | 11,493
Rheumatoid arthritis 14 | 1,191
malignant mesothelioma 14 | 3,232
Arthritis 13 | 290
Asthma 13 | 385
Multiple Sclerosis 13 | 540
tuberculosis 13 | 2,010
Hypersensitivity reaction type II disease 12 | 253
ulcerative colitis 12 | 1,819
Dermatitis 11 | 157
Inflammatory bowel disease 11 | 151
lung cancer 11 | 4,740
Anemia 10 | 365
Arthritis, Rheumatoid 10 | 174
Astrocytoma, Pilocytic 10 | 3,081
Fever 10 | 138
Inflammation 10 | 120
glioblastoma 10 | 5,792
interstitial cystitis 10 | 2,312
Candidiasis 9 | 55
Crohn's disease 9 | 321
Hypereosinophilic syndrome 9 | 71
Kidney disease 9 | 430
Pneumonia 9 | 174
cutaneous lupus erythematosus 9 | 1,057
diabetes mellitus 9 | 1,728
ependymoma 9 | 4,679
ovarian cancer 9 | 8,520
Allergic hypersensitivity disease 8 | 126
Atherosclerosis 8 | 291
Brain Ischemia 8 | 110
Heart disease 8 | 306
Hypersensitivity 8 | 63
Liver disease 8 | 237
Lung disease 8 | 142
Major Depressive Disorder 8 | 301
Schizophrenia 8 | 1,160
Vasculitis 8 | 80
medulloblastoma, large-cell 8 | 6,241
pancreatic cancer 8 | 2,398
sarcoidosis 8 | 370
Allergic rhinitis 7 | 94
Arthritis, Experimental 7 | 39
Collagen disease 7 | 27
Influenza 7 | 142
Leishmaniasis 7 | 47
Liver Cirrhosis 7 | 181
Liver carcinoma 7 | 240
Lung Neoplasms 7 | 232
Neoplasm Metastasis 7 | 168
Prostatic Neoplasms 7 | 495
atypical teratoid / rhabdoid tumor 7 | 5,112
cystic fibrosis 7 | 1,696
lung carcinoma 7 | 2,843
Biliary cirrhosis 6 | 45
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Breast cancer 6 | 3,578
Chemical and Drug Induced Liver Injury 6 | 195
Colitis 6 | 54
Coronary artery disease 6 | 268
Depressive disorder 6 | 409
Diarrhea 6 | 253
Glomerulonephritis 6 | 46
Hepatitis C 6 | 94
Liver Cirrhosis, Experimental 6 | 769
Mammary Neoplasms 6 | 425
Meningitis 6 | 67
Myocardial Infarction 6 | 151
Myocardial Ischemia 6 | 169
Obesity 6 | 678
Osteoporosis 6 | 363
Reperfusion Injury 6 | 86
Unipolar Depression 6 | 250
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
periodontitis 6 | 293
Abortion, Spontaneous 5 | 109
Carcinoma, Hepatocellular 5 | 228
Hepatitis B 5 | 108
Hepatitis, Autoimmune 5 | 17
Hypertension 5 | 396
Kidney cancer 5 | 2,613
Leukopenia 5 | 72
Liver neoplasms 5 | 130
Malaria 5 | 160
Mental Depression 5 | 333
Necrosis 5 | 53
Neuropathy 5 | 261
Spontaneous abortion 5 | 113
Stomach Neoplasms 5 | 300
Systemic lupus erythematosus 5 | 194
Thrombocytopenia 5 | 197
dermatomyositis 5 | 966
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890

Tissue

Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Skin and soft tissues 26 | 17,230
Female tissues 25 | 17,400
Urinary Tract 25 | 16,678
Endocrine System 24 | 18,159
Respiratory system 24 | 16,393
Nervous System 23 | 16,725
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 7 | 1,400
Kinase 3 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 26 | 26
http://pathwaycommons.org/pc2/... 137 | 137
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Interleukin-27 subunit alpha IL27 Tbio Non-IDG -1.81855 61.1 509
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Interleukin-12 subunit beta IL12B Tclin Non-IDG -1.21064 19.3 675
Signal transducer and activator of transcription 2 STAT2 Tbio Transcription Factor -2.43127 248.8 691
Interleukin-12 receptor subunit beta-1 IL12RB1 Tbio Non-IDG -2.33532 220.9 273
Signal transducer and activator of transcription 4 STAT4 Tbio Transcription Factor -2.51382 320.4 790
Interleukin-12 receptor subunit beta-2 IL12RB2 Tbio Non-IDG -1.54009 32.6 214
Non-receptor tyrosine-protein kinase TYK2 TYK2 Tclin Kinase -2.47105 252.9 547
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555