Development Level

Tbio 55 | 11,445
Tchem 21 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
decreased body weight 3 | 161
embryonic lethality prior to o... 3 | 239
preweaning lethality, incomple... 3 | 499
decreased circulating alkaline... 2 | 46
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
edema 2 | 59
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
male infertility 2 | 123
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal hair texture 1 | 4
abnormal snout morphology 1 | 23
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased sacral vertebrae num... 1 | 1
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
increased circulating calcium ... 1 | 34
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lumbar vertebrae num... 1 | 1
increased mean corpuscular vol... 1 | 92
increased sacral vertebrae num... 1 | 1
increased total body fat amoun... 1 | 134
short tibia 1 | 97
shortened RR interval 1 | 17
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

Carcinoma 56 | 11,493
Cancer 53 | 2,499
ovarian cancer 50 | 8,520
medulloblastoma, large-cell 42 | 6,241
psoriasis 42 | 6,694
lung cancer 39 | 4,740
osteosarcoma 39 | 7,950
glioblastoma 35 | 5,792
group 3 medulloblastoma 32 | 4,104
Breast cancer 28 | 3,578
atypical teratoid / rhabdoid tumor 27 | 5,112
non-small cell lung cancer 24 | 2,890
ependymoma 23 | 4,679
lung adenocarcinoma 23 | 2,716
primitive neuroectodermal tumor 22 | 3,035
oligodendroglioma 20 | 2,850
pancreatic cancer 20 | 2,398
Multiple myeloma 19 | 1,332
invasive ductal carcinoma 19 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
malignant mesothelioma 18 | 3,232
adult high grade glioma 17 | 3,801
colon cancer 17 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
Waldenstrons macroglobulinemia 15 | 765
diabetes mellitus 15 | 1,728
ductal carcinoma in situ 15 | 1,745
Astrocytoma, Pilocytic 14 | 3,081
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
adrenocortical carcinoma 14 | 1,428
astrocytoma 14 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
subependymal giant cell astrocytoma 13 | 2,287
ulcerative colitis 13 | 1,819
acute myeloid leukemia 12 | 783
acute quadriplegic myopathy 12 | 1,158
astrocytic glioma 12 | 2,597
nasopharyngeal carcinoma 12 | 1,058
Kidney cancer 11 | 2,613
Schizophrenia 11 | 1,160
interstitial cystitis 11 | 2,312
Adenocarcinoma of lung 10 | 142
Carcinoma, Hepatocellular 10 | 228
Disease Models, Animal 10 | 155
Epilepsy 10 | 792
Intellectual disability 10 | 1,016
Liver carcinoma 10 | 240
Neurodegenerative disease 10 | 414
Seizures 10 | 596
Stomach Neoplasms 10 | 300
Vascular disease 10 | 319
cystic fibrosis 10 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung carcinoma 10 | 2,843
tuberculosis 10 | 2,010
Anemia 9 | 365
Colorectal Neoplasms 9 | 243
Squamous cell carcinoma 9 | 129
breast carcinoma 9 | 1,638
esophageal adenocarcinoma 9 | 737
gastric carcinoma 9 | 807
non primary Sjogren syndrome sicca 9 | 891
pediatric high grade glioma 9 | 1,064
pituitary cancer 9 | 1,972
Autosomal recessive predisposition 8 | 1,442
Carcinoma, Squamous Cell 8 | 110
Cell Transformation, Neoplastic 8 | 97
Colonic Neoplasms 8 | 142
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Neoplastic Cell Transformation 8 | 89
Pick disease 8 | 1,894
Poor school performance 8 | 645
Prostatic Neoplasms 8 | 495
Short stature 8 | 531
dermatomyositis 8 | 966
non-small cell lung carcinoma 8 | 317
primary pancreatic ductal adenocarcinoma 8 | 1,109
Alzheimer's disease 7 | 658
Atopic dermatitis 7 | 952
Cognitive delay 7 | 608
Global developmental delay 7 | 608
HIV Infections 7 | 102
Lung Neoplasms 7 | 232
Mental and motor retardation 7 | 608
Neoplasm Metastasis 7 | 168
Osteoporosis 7 | 363
Rheumatoid arthritis 7 | 1,191
Small head 7 | 374
aldosterone-producing adenoma 7 | 665
Bipolar Disorder 6 | 666
Duchenne muscular dystrophy 6 | 601
Endometriosis 6 | 540
Immune system cancer 6 | 140
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
juvenile dermatomyositis 6 | 1,187
pancreatic carcinoma 6 | 562

Tissue

Blood and immune system 80 | 16,909
Digestive Tract 79 | 17,369
Endocrine System 79 | 18,159
Female tissues 78 | 17,400
Male tissues 78 | 17,142
Nervous System 78 | 16,725
Respiratory system 78 | 16,393
Skin and soft tissues 78 | 17,230
Cardiovascular System 77 | 15,192
Liver and Pancreas 77 | 16,750
Urinary Tract 77 | 16,678

Target Family

Non-IDG 41 | 12,091
Enzyme 14 | 4,145
Transcription Factor 13 | 1,400
Kinase 6 | 634
Epigenetic 5 | 242
Transporter 1 | 473

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
ATP-dependent RNA helicase DDX18 DDX18 Tbio Enzyme -0.74619 5.48 53
Iron-responsive element-binding protein 2 IREB2 Tbio Non-IDG -2.33609 211.7 253
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Protein lin-28 homolog B LIN28B Tbio Transcription Factor -2.08968 113.4 204
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
STAGA complex 65 subunit gamma SUPT7L Tdark Non-IDG -0.46246 2.75 76
Transcription initiation factor TFIID subunit 10 TAF10 Tbio Non-IDG -1.26261 15.2 107
Ribosomal oxygenase 2 RIOX2 Tbio Epigenetic -1.39182 29.9 271