Development Level

Tbio 13 | 11,445
Tchem 13 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
cataract 1 | 92
edema 1 | 59
enlarged lymph nodes 1 | 37
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Cancer 26 | 2,499
ovarian cancer 25 | 8,520
Carcinoma 23 | 11,493
osteosarcoma 19 | 7,950
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 13 | 5,112
lung cancer 13 | 4,740
oligodendroglioma 13 | 2,850
ependymoma 12 | 4,679
psoriasis 12 | 6,694
group 4 medulloblastoma 11 | 1,855
Kidney cancer 10 | 2,613
astrocytic glioma 10 | 2,597
breast carcinoma 9 | 1,638
diabetes mellitus 9 | 1,728
group 3 medulloblastoma 9 | 4,104
Hypoplastic mandible condyle 8 | 275
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Schizophrenia 8 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
Breast Neoplasms 7 | 445
Delayed bone age 7 | 136
Downward slant of palpebral fissure 7 | 158
Hyperglycemia 7 | 137
Mammary Neoplasms 7 | 425
Obesity 7 | 678
Orbital separation excessive 7 | 244
Short stature 7 | 531
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pediatric high grade glioma 7 | 1,064
Bipolar Disorder 6 | 666
Blepharoptosis 6 | 231
Byzanthine arch palate 6 | 194
Carcinoma, Hepatocellular 6 | 228
Carcinoma, Squamous Cell 6 | 110
Cognitive delay 6 | 608
Congenital Epicanthus 6 | 177
Dull intelligence 6 | 645
Fetal Growth Retardation 6 | 189
Global developmental delay 6 | 608
Hyperinsulinism 6 | 133
Infant, Small for Gestational Age 6 | 176
Intellectual disability 6 | 1,016
Intrauterine retardation 6 | 176
Liver carcinoma 6 | 240
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Muscle hypotonia 6 | 571
Pectus excavatum 6 | 100
Pick disease 6 | 1,894
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Squamous cell carcinoma 6 | 129
adult high grade glioma 6 | 3,801
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
Acquired scoliosis 5 | 281
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
Cell Transformation, Neoplastic 5 | 97
Concave bridge of nose 5 | 195
Curvature of spine 5 | 282
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
High forehead 5 | 102
Hypertension 5 | 396
Insulin Resistance 5 | 72
Joint hyperflexibility 5 | 78
Mammary Neoplasms, Experimental 5 | 154
Melanocytic nevus 5 | 43
Noncancerous mole 5 | 28
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Short neck 5 | 140
Tall forehead 5 | 102
astrocytoma 5 | 1,146
juvenile dermatomyositis 5 | 1,187
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Hepatomegaly 4 | 285
Leukemia 4 | 104
Polycystic ovary syndrome 4 | 360
Strabismus 4 | 270
Ventricular Septal Defects 4 | 119
dermatomyositis 4 | 966
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955

Tissue

Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678

Target Family

Non-IDG 16 | 12,091
Kinase 11 | 634
Enzyme 3 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Ribosomal protein S6 kinase beta-1 RPS6KB1 Tchem Kinase -3.18361 0.00000 1818
Insulin-like growth factor 1 receptor IGF1R Tclin Kinase -3.37168 2419.5 1686
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Serine/threonine-protein kinase D1 PRKD1 Tchem Kinase -2.88440 775.2 667
Growth factor receptor-bound protein 10 GRB10 Tbio Non-IDG -1.98746 111.0 315
Paxillin PXN Tbio Non-IDG -2.99437 902.9 1251
Receptor of activated protein C kinase 1 RACK1 Tbio Non-IDG -2.60480 437.9 300