Development Level

Tbio 18 | 11,445
Tchem 14 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal bone structure 2 | 187
increased circulating triglyce... 2 | 42
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
increased body length 1 | 32
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39

Disease

Cancer 29 | 2,499
Carcinoma 28 | 11,493
ovarian cancer 23 | 8,520
osteosarcoma 21 | 7,950
glioblastoma 20 | 5,792
diabetes mellitus 17 | 1,728
atypical teratoid / rhabdoid tumor 16 | 5,112
lung cancer 16 | 4,740
psoriasis 14 | 6,694
Breast cancer 13 | 3,578
ependymoma 13 | 4,679
lung carcinoma 13 | 2,843
medulloblastoma, large-cell 13 | 6,241
malignant mesothelioma 12 | 3,232
pancreatic cancer 12 | 2,398
Heart disease 11 | 306
Schizophrenia 11 | 1,160
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Arthritis 10 | 290
Astrocytoma, Pilocytic 10 | 3,081
Kidney disease 10 | 430
Vascular disease 10 | 319
cystic fibrosis 10 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
oligodendroglioma 10 | 2,850
Kidney cancer 9 | 2,613
Neoplasm Invasiveness 9 | 161
Short stature 9 | 531
Stomach Neoplasms 9 | 300
adult high grade glioma 9 | 3,801
primitive neuroectodermal tumor 9 | 3,035
ulcerative colitis 9 | 1,819
Breast Neoplasms 8 | 445
Carcinoma, Squamous Cell 8 | 110
Hypertension 8 | 396
Hypertensive disease 8 | 292
Intellectual disability 8 | 1,016
Lung disease 8 | 142
Mammary Neoplasms 8 | 425
Squamous cell carcinoma 8 | 129
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
Asthma 7 | 385
Cerebrovascular disease 7 | 238
Colorectal Neoplasms 7 | 243
Prostatic Neoplasms 7 | 495
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
primary pancreatic ductal adenocarcinoma 7 | 1,109
tuberculosis 7 | 2,010
Animal Mammary Neoplasms 6 | 136
Atherosclerosis 6 | 291
Autosomal recessive predisposition 6 | 1,442
Cognitive delay 6 | 608
Depressive disorder 6 | 409
Duchenne muscular dystrophy 6 | 601
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Hyperalgesia 6 | 83
Liver Cirrhosis, Experimental 6 | 769
Low intelligence 6 | 645
Mammary Neoplasms, Animal 6 | 136
Melanoma 6 | 711
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Muscle Weakness 6 | 170
Neoplasm Metastasis 6 | 168
Obesity 6 | 678
Orbital separation excessive 6 | 244
Osteoporosis 6 | 363
Poor school performance 6 | 645
Rheumatoid arthritis 6 | 1,191
breast carcinoma 6 | 1,638
pituitary cancer 6 | 1,972
Bipolar Disorder 5 | 666
Carcinoma, Hepatocellular 5 | 228
Down syndrome 5 | 499
Epilepsy 5 | 792
Eye disease 5 | 62
Hypersensitivity reaction type II disease 5 | 253
Inflammatory bowel disease 5 | 151
Liver carcinoma 5 | 240
Mental Depression 5 | 333
Multiple Sclerosis 5 | 540
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287

Tissue

Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 22 | 12,091
Kinase 11 | 634
Enzyme 5 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 19 FGF19 Tbio Non-IDG -2.54882 334.2 305
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Caveolin-2 CAV2 Tbio Non-IDG -2.43448 254.2 294
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Fibroblast growth factor 23 FGF23 Tbio Non-IDG -3.19500 1726.4 296
Fibroblast growth factor receptor 4 FGFR4 Tclin Kinase -2.44255 276.4 502
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227