Development Level

Tbio 14 | 11,445
Tchem 11 | 1,598
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal retina morphology 2 | 71
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating sodium l... 1 | 22
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
pallor 1 | 34
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 25 | 11,493
Cancer 23 | 2,499
diabetes mellitus 19 | 1,728
glioblastoma 17 | 5,792
Breast cancer 16 | 3,578
Kidney disease 16 | 430
invasive ductal carcinoma 16 | 2,951
osteosarcoma 16 | 7,950
ovarian cancer 16 | 8,520
psoriasis 16 | 6,694
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
ulcerative colitis 15 | 1,819
Atherosclerosis 14 | 291
Hypertension 14 | 396
interstitial cystitis 14 | 2,312
lung adenocarcinoma 14 | 2,716
non-small cell lung cancer 14 | 2,890
pancreatic cancer 14 | 2,398
Heart disease 13 | 306
cystic fibrosis 13 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
ependymoma 12 | 4,679
lung cancer 12 | 4,740
Cerebrovascular disease 11 | 238
Kidney cancer 11 | 2,613
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Astrocytoma, Pilocytic 10 | 3,081
Hypertensive disease 10 | 292
Myocardial Infarction 10 | 151
Schizophrenia 10 | 1,160
atypical teratoid / rhabdoid tumor 10 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Arthritis 9 | 290
Coronary artery disease 9 | 268
Liver Cirrhosis, Experimental 9 | 769
Liver disease 9 | 237
Obesity 9 | 678
medulloblastoma, large-cell 9 | 6,241
mucosa-associated lymphoid tissue lymphoma 9 | 484
tuberculosis 9 | 2,010
Alzheimer's disease 8 | 658
Asthma 8 | 385
Brain Ischemia 8 | 110
Hypersensitivity reaction type II disease 8 | 253
Inflammation 8 | 120
Lung disease 8 | 142
Neoplasm Invasiveness 8 | 161
cutaneous lupus erythematosus 8 | 1,057
oligodendroglioma 8 | 2,850
primary pancreatic ductal adenocarcinoma 8 | 1,109
Chemical and Drug Induced Liver Injury 7 | 195
Duchenne muscular dystrophy 7 | 601
Endometriosis 7 | 540
Inflammatory bowel disease 7 | 151
Multiple Sclerosis 7 | 540
Neoplasm Metastasis 7 | 168
Reperfusion Injury 7 | 86
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
periodontitis 7 | 293
Autosomal recessive predisposition 6 | 1,442
Cerebrovascular accident 6 | 63
Cholestasis, Extrahepatic 6 | 25
Osteoporosis 6 | 363
Peritonitis 6 | 43
Pneumonia 6 | 174
Pulmonary Fibrosis 6 | 106
Rheumatoid arthritis 6 | 1,191
Stroke 6 | 33
gastric carcinoma 6 | 807
Alcoholic Intoxication, Chronic 5 | 289
Aortic aneurysm 5 | 38
Arthritis, Rheumatoid 5 | 174
Bipolar Disorder 5 | 666
Brain disease 5 | 96
Breast Neoplasms 5 | 445
Crohn's disease 5 | 321
Dermatitis 5 | 157
Diabetes Mellitus, Experimental 5 | 108
Hyperglycemia 5 | 137
Infarction, Middle Cerebral Artery 5 | 33
Lipid metabolism disorder 5 | 114
Melanoma 5 | 711
Myocardial Ischemia 5 | 169
Peripheral vascular disease 5 | 87
Prostatic Neoplasms 5 | 495
Thrombocytopenia 5 | 197
Vascular disease 5 | 319
acute myeloid leukemia 5 | 783
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
interstitial lung disease 5 | 298
nasopharyngeal carcinoma 5 | 1,058
Glaucoma 4 | 239
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Male tissues 32 | 17,142
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Respiratory system 31 | 16,393
Blood and immune system 30 | 16,909
Nervous System 30 | 16,725
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 11 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Ras-related protein Rap-1b RAP1B Tbio Enzyme -2.38904 417.6 114
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Integrin alpha-M ITGAM Tbio Non-IDG -3.63427 3939.5 2165
Junctional adhesion molecule B JAM2 Tbio Non-IDG -1.72934 50.6 302
Hepatocyte growth factor-like protein MST1 Tbio Enzyme -2.04160 93.5 0
Tissue-type plasminogen activator PLAT Tclin Enzyme -3.71677 5819.3 555
Advanced glycosylation end product-specific receptor AGER Tchem Non-IDG -2.29145 187.3 589
Tyrosine-protein kinase HCK HCK Tclin Kinase -3.53517 3192.7 428
Apolipoprotein(a) LPA Tbio Enzyme -3.51111 3598.6 227