Development Level

Tbio 38 | 11,445
Tchem 21 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal eye morphology 2 | 68
abnormal retina morphology 2 | 71
decreased grip strength 2 | 116
enlarged heart 2 | 210
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal startle reflex 1 | 15
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19

Disease

Carcinoma 52 | 11,493
ovarian cancer 44 | 8,520
osteosarcoma 37 | 7,950
Cancer 35 | 2,499
lung cancer 34 | 4,740
glioblastoma 28 | 5,792
medulloblastoma, large-cell 28 | 6,241
psoriasis 28 | 6,694
Breast cancer 25 | 3,578
malignant mesothelioma 22 | 3,232
atypical teratoid / rhabdoid tumor 21 | 5,112
group 3 medulloblastoma 20 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
primitive neuroectodermal tumor 18 | 3,035
Kidney cancer 16 | 2,613
ependymoma 16 | 4,679
Prostatic Neoplasms 15 | 495
astrocytoma 14 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
pancreatic cancer 14 | 2,398
adult high grade glioma 13 | 3,801
invasive ductal carcinoma 13 | 2,951
non-small cell lung cancer 13 | 2,890
Pick disease 12 | 1,894
breast carcinoma 12 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
oligodendroglioma 12 | 2,850
Astrocytoma, Pilocytic 11 | 3,081
Schizophrenia 11 | 1,160
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
lung adenocarcinoma 11 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Multiple myeloma 10 | 1,332
lung carcinoma 10 | 2,843
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Rheumatoid arthritis 9 | 1,191
ductal carcinoma in situ 9 | 1,745
pituitary cancer 9 | 1,972
tuberculosis 9 | 2,010
Intellectual disability 8 | 1,016
Obesity 8 | 678
Prostate cancer 8 | 175
dermatomyositis 8 | 966
subependymal giant cell astrocytoma 8 | 2,287
Carcinoma, Hepatocellular 7 | 228
Melanoma 7 | 711
Vascular disease 7 | 319
astrocytic glioma 7 | 2,597
colon cancer 7 | 1,478
gastric carcinoma 7 | 807
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
pediatric high grade glioma 7 | 1,064
Dull intelligence 6 | 645
Liver cancer 6 | 604
Liver carcinoma 6 | 240
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Skin cancer 6 | 469
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
medulloblastoma 6 | 720
nasopharyngeal carcinoma 6 | 1,058
spina bifida 6 | 1,074
Bipolar Disorder 5 | 666
Colorectal Neoplasms 5 | 243
Epilepsy 5 | 792
Liver Cirrhosis, Experimental 5 | 769
Lung Neoplasms 5 | 232
Mammary Neoplasms, Experimental 5 | 154
Muscle hypotonia 5 | 571
Small head 5 | 374
Stomach Neoplasms 5 | 300
acute myeloid leukemia 5 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
hepatocellular carcinoma 5 | 547
juvenile dermatomyositis 5 | 1,187
Adenoma 4 | 167
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Crohn's disease 4 | 321
Depressive disorder 4 | 409
Disease Progression 4 | 136
Endometrial cancer 4 | 311
Endometriosis 4 | 540
Immune system cancer 4 | 140
Mental and motor retardation 4 | 608
Neoplasm Invasiveness 4 | 161
Polycystic ovary syndrome 4 | 360
Seizures 4 | 596
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
primary pancreatic ductal adenocarcinoma 4 | 1,109
ulcerative colitis 4 | 1,819

Tissue

Blood and immune system 58 | 16,909
Digestive Tract 58 | 17,369
Endocrine System 58 | 18,159
Female tissues 58 | 17,400
Liver and Pancreas 58 | 16,750
Male tissues 58 | 17,142
Nervous System 58 | 16,725
Respiratory system 58 | 16,393
Urinary Tract 58 | 16,678
Skin and soft tissues 57 | 17,230
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 11 | 4,145
Transcription Factor 9 | 1,400
Kinase 8 | 634
Epigenetic 4 | 242
Nuclear Receptor 1 | 48

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SNRPN upstream reading frame protein SNURF Tbio Non-IDG -1.05125 8.44 12
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
Lysine-specific demethylase 3A KDM3A Tchem Epigenetic -1.83544 74.7 253
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
POZ-, AT hook-, and zinc finger-containing protein 1 PATZ1 Tbio Transcription Factor -1.98463 95.1 106
Ribosomal protein S6 kinase alpha-3 RPS6KA3 Tchem Kinase -2.50143 325.4 425
E3 SUMO-protein ligase PIAS3 PIAS3 Tbio Transcription Factor -1.74449 53.4 174
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
Nuclear receptor-interacting protein 1 NRIP1 Tbio Non-IDG -2.21323 183.8 155
Transforming growth factor beta-1-induced transcript 1 protein TGFB1I1 Tbio Non-IDG -1.82580 89.7 147